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E-096 COVID status is related to clot burden during thrombectomy in acute stroke patients
ConclusionOf 230 patients included in this interim analysis across 24 centers in the United States, between 02/2021 and 01/2022, 16 patients had a history of COVID. Comparing COVID-positive to non-positive, patients with COVID were younger (median 66.5 years vs 71.5 years, p 0.042), and had more intracranial clot by weight (median 101.0 mg vs 42.0 mg, p 0.047). There was a trend toward COVID positive patients to have more clot volume (median 180 cc vs 77.5 cc p 0.08), suggesting the difference was a higher clot burden instead of more density to the thrombus. These results suggest different histopathological characteristics...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Dabney, A., Vicari, J., Rivet, D., Woodward, B., Nanda, A., Fiorella, D., Baltan, S., Sohrabji, F., Pennypacker, K., Kellner, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Iatrogenesis imperfecta: stroke caused by accidental carotid artery catheterization.
CONCLUSION:: Even with ultrasound-guided central venous catheterization, it is essential to remain vigilant for the early detection of vascular complications. Clinical suspicion combined with diagnostic modalities such as chest radiograph, transduction and manometry can increase the detection rates. PMID: 25041919 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - November 27, 2014 Category: Surgery Tags: J Vasc Access Source Type: research

Association of clot burden score with radiographic and clinical outcomes following Solitaire stent retriever thrombectomy: analysis of the SWIFT PRIME trial
Conclusions The combination of IV thrombolysis and stent retriever thrombectomy with the Solitaire device is highly effective in achieving successful recanalization and a good clinical outcome throughout the entire range of CBS values.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Mokin, M., Levy, E. I., Siddiqui, A. H., Goyal, M., Nogueira, R. G., Yavagal, D. R., M Pereira, V., Saver, J. L. Tags: Ischemic stroke Source Type: research

LB-005 The INSIGHT registry: a multi-center, multi-omic stroke clot study, preliminary results
ConclusionThese preliminary results demonstrate the real-world applicability of the INSIGHT study to typical stroke thrombectomy population. Furthermore, the tissue processing protocols are providing high-quality RNA and protein for analysis, which is currently underway.DisclosuresJ. Fraser: 1; C; Penumbra, University of Kentucky. 2; C; Stream Biomedical, Medtronic. 4; C; Cerelux, Fawkes Biotechnology. J. Vicari: None. A. Nanda: None. E. Cheng-Ching: None. K. Woodward: None. B. Rapoport: None. C. Kellner: None.
Source: Journal of NeuroInterventional Surgery - July 29, 2021 Category: Neurosurgery Authors: Fraser, J., Vicari, J., Nanda, A., Cheng-Ching, E., Woodward, K., Rapoport, B., Kellner, C. Tags: Late-breaking oral abstracts Source Type: research

O-020 The tigertriever 13 distals study: distal ischemic stroke treatment with adjustable low-profile stentriever
ConclusionThe TIGERTRIEVER 13 device with operator controllability and high fluoroscopy visibility and its small size can potentially provide a safe and effective clot removal in patients with distal vessels occlusion.Disclosures D. Fiorella: 1; C; Rapid Medical. R. Gupta: None. R. Chapot: None. J. Saver: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fiorella, D., Gupta, R., Chapot, R., Saver, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

Simultaneous onset of myocardial infarction and ischemic stroke in a patient with atrial fibrillation: Multiple territory injury revealed on angiography and magnetic resonance
An 84-year-old man with a history of hypertension and paroxysmal atrial fibrillation (AF) who received no anticoagulant drugs experienced acute chest pain and transient loss of consciousness. He was transferred to our emergency room. His initial electrocardiogram showed sinus rhythm with ST-segment elevation in the I, aVL, and V1–V6 leads. His blood pressure was 158/92mmHg and his pulse was regular at 70beats per minute. A chest radiograph showed increased heart size and pulmonary vascular congestion. His troponin T level was elevated (more than 0.1ng/mL). He was diagnosed with ST-elevation myocardial infarction (MI) and...
Source: International Journal of Cardiology - February 4, 2014 Category: Cardiology Authors: Osamu Hashimoto, Kozo Sato, Yohei Numasawa, Joji Hosokawa, Masahiro Endo Tags: Online Letters to the Editor Source Type: research

Repeated Mechanical Thrombectomy in the Same Intracranial Artery Segment
We report a patient with an important scenario that may arise in the management of an acute ischemic stroke: the need for a repeated mechanical thrombectomy in the same intracranial artery segment. The patient had a history of atrial fibrillation and a mechanical mitral valve replacement. In her first stroke, she had an occlusion of the proximal segment of the right middle cerebral artery; 58 days later, she presented with an occlusion in the same segment of that cerebral artery. In both instances, the thrombus was extracted by a stent retriever with good clinical and radiographic results.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2017 Category: Neurology Authors: Herbert Tejada Meza, Maria Rosario Barrena Caballo, Santiago Guelbenzu Morte, Roberto Mart ínez García, Javier Marta Moreno Tags: Case Studies Source Type: research

Telemedicine remote controlled stroke evaluation and treatment, the experience of radiographers, paramedics and junior doctors in a novel rural stroke management team
In the case of ischemic stroke, access to a Computed Tomography (CT) scanner and the start of thrombolytic therapy immediately is imperative. Transport to the nearest hospital from the remote, rural area of Ha...
Source: BMC Health Services Research - June 5, 2021 Category: General Medicine Authors: Elin Kjelle and Aud Mette Myklebust Tags: Research Source Type: research

Pediatric Cortical Vein Thrombosis: Frequency and Association With Venous Infarction Brief Reports
Conclusions— In our cohort, CVT was significantly associated with seizures at presentation, hemorrhage and restricted diffusion on acute imaging, as well as neurological disability and venous infarction at follow-up. Involvement of cortical veins in cerebral sinovenous thrombosis is associated with an increased risk of infarction and adverse outcome in children.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Ritchey, Z., Hollatz, A. L., Weitzenkamp, D., Fenton, L. Z., Maxwell, E. C., Bernard, T. J., Stence, N. V. Tags: Pediatrics, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Endovascular mechanical thrombectomy for cerebral venous sinus thrombosis: a systematic review
Conclusions EMT is an effective salvage therapy for refractory CVST, with a reasonable safety profile. Chemical thrombolysis, in conjunction with EMT, did not appear to result in additional harm or benefit. Further analysis is warranted to determine predictors of success after EMT for CVST.
Source: Journal of NeuroInterventional Surgery - October 13, 2017 Category: Neurosurgery Authors: Ilyas, A., Chen, C.-J., Raper, D. M., Ding, D., Buell, T., Mastorakos, P., Liu, K. C. Tags: Ischemic stroke Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

P-001 Permanent Implantation of the Solitaire Device as a Bailout Technique for Large Vessel Intracranial Occlusions
ConclusionWith the recent over-whelming evidence demonstrating the effectiveness endovascular therapy in acute ischemic stroke, the expansion of stroke therapy requires that a variety of techniques be available to the operators. Permanent implantation of the Solitaire stent achieves adequate distal flow and good clinical outcomes in the setting of AIS. This case series suggests this technique provides a safe alternative for difficult cases refractory to other revascularization techniques.Key Wordsstroke, revascularization, stentDisclosuresJ. Houde: None. E. Barber: None. M. Kelly: 2; C; Medtronic. 4; C; Blockade. 6; C; Pen...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Houde, J., Barber, E., Kelly, M., Peeling, L. Tags: Oral poster abstracts Source Type: research

To Treat or Not to Treat M2 Occlusions? The Question (and Answer) From a Single Institution
CONCLUSION: The results of our single-institution experience suggest that endovascular therapy for M2 occlusions is safe and effective. Additional evaluation with randomized, controlled studies is warranted. ABBREVIATIONS: ADAPT, direct aspiration first-pass technique ECASS, European-Australasian Cooperative Acute Stroke Study ICH, intracranial hemorrhage IMS, Interventional Management of Stroke MERCI, Mechanical Embolus Removal in Cerebral Ischemia mRS, modified Rankin Scale NIHSS, National Institutes of Health Stroke Scale PROACT, Prolyse in Acute Cerebral Thromboembolism TICI, Thrombolysis in Cerebral Infarctio...
Source: Neurosurgery - September 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Bm-12 * cerebral infarction secondary to pulmonary vein compression and left atrial appendage tumor infiltration as the presenting sign of metastatic squamous cell carcinoma of the base of the tongue
CONCLUSION: Cardiac metastases are rare and non-myxomatous tumor embolization to the brain even rarer especially in the setting of cerebral infarction due to pulmonary vein thrombus. Here we describe a case of multiple acute cerebral infarctions appearing from a proximal source refractory to anticoagulation. Thromboembolism from the pulmonary vein and tumor embolization from cardiac metastases are the likely mechanisms for his clinical presentation and radiographic findings. This case demonstrates the complexity of multiple stroke etiologies in one patient and the importance of cardiac imaging in stroke evaluation, particu...
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Dredla, B., Siegel, J., Jaeckle, K. Tags: BRAIN METASTASES (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

Hemodynamic outcomes of stenting for vertebrobasilar insufficiency in patients with a low flow state
CONCLUSIONS: Our series demonstrates angioplasty and stenting significantly improve intracranial flow over long-term. Angioplasty and stenting may improve the natural history of low-flow VB atherosclerotic disease.PMID:37386804 | DOI:10.1177/15910199231185801
Source: Interventional Neuroradiology - June 30, 2023 Category: Radiology Authors: Timothy G White Richard Bram Justin Turpin Kevin A Shah Prateeka Koul Thomas Link Ali Alaraj Athos Patsalides Sepideh Amin-Hanjani Henry H Woo Source Type: research

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