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Iatrogenesis imperfecta: stroke caused by accidental carotid artery catheterization.
CONCLUSION:: Even with ultrasound-guided central venous catheterization, it is essential to remain vigilant for the early detection of vascular complications. Clinical suspicion combined with diagnostic modalities such as chest radiograph, transduction and manometry can increase the detection rates. PMID: 25041919 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - November 27, 2014 Category: Surgery Tags: J Vasc Access Source Type: research

Paradoxical embolism through a patent foramen ovale from central venous catheter thrombosis: A potential cause of stroke
Paradoxical embolism refers to a potential condition in which an embolus arising from a venous source crosses into the systemic circulation through a right-to-left cardiac shunt causing an arterial embolism.A 39-year-old woman carrier of a central venous catheter (CVC) without evident risk factors for stroke, developed an acute right homonymous hemianopia during hemodialysis. On neuroimaging, an infarct in the territory of the left posterior cerebral artery was demonstrated. Transesophageal echocardiography revealed a patent foramen ovale (PFO) and a large fluctuating thrombus in the right atrium on the tip of the CVC, thu...
Source: Journal of the Neurological Sciences - April 3, 2020 Category: Neurology Authors: Di Stefano Vincenzo, Di Fulvio Maria, Di Liberato Lorenzo, Onofrj Marco, De Angelis Maria Vittoria Tags: Clinical Short Communication Source Type: research

Proteomic and other mass spectrometry‐based “Omics” biomarker discovery and validation in pediatric venous thromboembolism and arterial ischemic stroke: Current state, unmet needs, and future directions
This article is protected by copyright. All rights reserved
Source: Proteomics. Clinical Applications - October 1, 2014 Category: Biochemistry Authors: Neil A. Goldenberg, Allen D. Everett, David Graham, Timothy J. Bernard, Ulrike Nowak‐Göttl Tags: Review Source Type: research

Proteomic and other mass spectrometry based “omics” biomarker discovery and validation in pediatric venous thromboembolism and arterial ischemic stroke: Current state, unmet needs, and future directions
Venous thromboembolism (VTE) and arterial ischemic stroke (AIS) are increasingly‐recognized health conditions in children, with both acute and chronic sequelae. Risk factors for, and pathogenesis of, VTE are readily related to three principal factors, consisting of venous stasis, endothelial damage, and the hypercoagulable state (i.e. thrombophilia), termed the triad of Virchow. In children, greater than 90% of VTE are provoked by an overt clinical risk factor, the most common of which is a central venous catheter. Risk factors for childhood‐onset (beyond the neonatal period) AIS include sickle cell disease, infection,...
Source: Proteomics. Clinical Applications - December 2, 2014 Category: Biochemistry Authors: Neil A. Goldenberg, Allen D. Everett, David Graham, Timothy J. Bernard, Ulrike Nowak‐Göttl Tags: Review Source Type: research

Thrombolysis Following Central Venous Catheter Placement
Since the importance of time in the treatment of hyperacute ischemic stroke became widely known, the frequency of thrombolysis has been gradually increasing.1,2 As thrombolytic agents are infusion formulations, securing a venous access route is mandatory.
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2020 Category: Neurology Authors: Kenichi Sakuta, Ryoji Nakada, Shinji Miyagawa, Izumu Hasegawa, Hiroshi Yaguchi Tags: Case Report Source Type: research

Significance of Echocardiographically Detected Central Venous Catheter Tip –Associated Thrombi
Conclusions In this sample with CVC tip–associated thrombi but without PFO or other intracardiac shunts, no embolic or other complications were detected, regardless of anticoagulation status. These data suggest a benign course for such thrombi and that anticoagulation, catheter removal, thrombectomy, and thrombolysis may be unnecessary when catheter tip–associated thrombi are incidentally detected on echocardiography.
Source: Journal of Vascular and Interventional Radiology - September 19, 2016 Category: Radiology Source Type: research

Systemic treatments for the prevention of venous thrombo-embolic events in paediatric cancer patients with tunnelled central venous catheters.
CONCLUSIONS: We found no significant effects of systemic treatments compared with no intervention in preventing (a)symptomatic VTE in paediatric oncology patients with CVCs. However, this could be a result of the low number of included participants, which resulted in low power. In one CCT, which compared one systemic treatment with another systemic treatment, we identified a significant reduction in symptomatic VTE with the addition of LMWH to AT supplementation.All studies investigated the prevalence of major and/or minor bleeding episodes, and none found a significant difference between study groups. None of the studies ...
Source: Cochrane Database of Systematic Reviews - September 11, 2013 Category: Journals (General) Authors: Schoot RA, Kremer LC, van de Wetering MD, van Ommen CH Tags: Cochrane Database Syst Rev Source Type: research

Case of Paradoxical Embolic Transient Ischemic Attack from an Unusual Extra Cardiac Shunt Detected on a Contrast‐Enhanced Echocardiogram
We describe a case of 63‐year‐old female who presented with a transient ischemic attack and at agitated saline contrast echocardiogram was found to have an unusual type of an extracardiac RLS. Further evaluation leads to diagnosis of superior vena cava (SVC) thrombosis from a prior indwelling central venous catheter. The SVC thrombosis induced systemic‐pulmonary venous collaterals were responsible for this unusual extracardiac RLS and paradoxical transient ischemic attack. We discuss the diagnosis and management of this rare clinical case.
Source: Echocardiography - November 1, 2013 Category: Cardiology Authors: Mujeeb Sheikh, Marie Emery, Allison Curtis, Stacie King, William R. Colyer Tags: Case Report Source Type: research

Arterial Closure Devices for Treatment of Inadvertent Large-Caliber Catheter Insertion Into the Subclavian or Carotid Artery: A Case Series of Five Patients
CENTRAL VENOUS CATHETERIZATION is a common procedure in today`s medicine. Iatrogenic complications occur in up to 34% of catheter placements including 5% of arterial puncture. A variety of complications by arterial puncture have recently been described, including airway obstruction, pseudoaneurysms, arteriovenous fistulas, and even stroke caused by arterial thrombosis or embolization. Although 2-D ultrasound assisted insertion of large central venous catheters may reduce adverse events, it might not be available in an emergency setting, and the use of ultrasound guidance requires training. Depending on anatomic localizatio...
Source: Journal of Cardiothoracic and Vascular Anesthesia - September 9, 2013 Category: Anesthesiology Authors: Arno Stellmes, Nicolas Diehm, Malte Book, Jürg Schmidli, Dai-Do Do, Jan Gralla Tags: Case Reports Source Type: research

Venous thromboembolism in children with acute lymphoblastic leukemia
Abstract Venous thromboembolism (VTE) occurs in 0.95–36 % of children with acute lymphoblastic leukemia almost exclusively during chemotherapy. It is most commonly associated with concurrent l-asparaginase and steroid therapy, central venous line use, and inherited thrombophilia. Clinical manifestations regarding the location of VTE include central nervous system thrombosis (sinus venous thrombosis, cerebral infarct/stroke), upper-/lower-limb deep venous thrombosis, pulmonary embolism, and right atrial/intracardiac and superficial venous thrombosis and can be both symptomatic and asymptomatic. The majority of ...
Source: Memo - Magazine of European Medical Oncology - September 1, 2014 Category: Cancer & Oncology Source Type: research

Duplex sonography for detection of deep vein thrombosis of upper extremities: a 13-year experience.
CONCLUSIONS. Upper-extremity deep vein thrombosis is uncommon among symptomatic Chinese population. The most common sign is swelling and the major risk factor for upper-extremity deep vein thrombosis identified in this study is malignancy. PMID: 25722467 [PubMed - as supplied by publisher]
Source: Hong Kong Med J - February 27, 2015 Category: Journals (General) Authors: Chung AS, Luk WH, Lo AX, Lo CF Tags: Hong Kong Med J Source Type: research

Inadvertent Arterial Placement of Central Venous Catheters: Diagnostic and Therapeutic Strategies
Central venous catheterization (CVC) is among the most ubiquitous medical procedures. Inadvertent arterial placement of the catheter presents a challenging dilemma to the interventionalist. Treatment options include: removal and manual compression, off-label use of percutaneous closure devices and/or stent grafts, and open surgical removal. Potential sequelae include bleeding, thrombosis, stroke, limb ischemia, neurologic deficit, and death. Our aim is to evaluate the use of open and endovascular techniques for the management of iatrogenic carotid, subclavian, and brachiocephalic arterial injuries related to inadvertent ar...
Source: Annals of Vascular Surgery - August 6, 2015 Category: Surgery Authors: Dustin Y. Yoon, Suman Annambhotla, Scott A. Resnick, Mark K. Eskandari, Heron E. Rodriguez Source Type: research

French Intensive Care Society, International congress - Réanimation 2016.
C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guérin C, Dellamonica J, Jaber S, Similowski T, Quenot JP, Binquet C, Vinsonneau C, Barbar SD, Vinault S, Deckert V, Lemaire S, Hssain AA, Bruyère R, Souweine B, Lagrost L, Adrie C, Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, Molinari N, Lheureux O, Trepo E, Hites M, Cotton F, Wolff F, Surin R, Créteur J, Vincent JL, Gustot T, Jacobs F, Taccone FS, Neuville M, Timsit JF, El-Hel...
Source: Australian Family Physician - May 31, 2016 Category: Primary Care Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubi Tags: Ann Intensive Care Source Type: research

Subclavian site should be preferred for central venous access
Commentary on: Parienti JJ, Mongardon N, Mégarbane B, et al.., 3SITES Study Group. Intravascular Complications of Central Venous Catheterization by Insertion Site. N Engl J Med 2015;373:1220–9. Implications for practice and research Subclavian site should be preferred for central venous access (CVA) with a low risk of pneumothorax. Excluding patients before randomisation represents a selection bias. Post hoc sensitivity analysis may reduce the bias without fully balancing it. An adjudication committee, unaware of study-group assignments, may compensate for the absence of feasible blindness. Context Infection, ...
Source: Evidence-Based Nursing - September 21, 2016 Category: Nursing Authors: Mourvillier, B., Radjou, A., Timsit, J.-F. Tags: Health policy, Nursing issues, Drugs: infectious diseases, Drugs: cardiovascular system, Stroke, Ophthalmology, Venous thromboembolism, Health service research Source Type: research

Predictors of venous thromboembolism recurrence and the bleeding events identified using a Japanese healthcare database.
CONCLUSIONS: These findings obtained from healthcare database suggest predictors either for recurrent VTE and bleeding that should be considered when selecting treatment to reduce the risk of recurrent VTE and mitigate bleeding. PMID: 28245956 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - February 24, 2017 Category: Cardiology Authors: Nakamura M, Yamada N, Oda E, Matsubayashi D, Ota K, Kobayashi M, Matsushita Y, Kaburagi J, Ibusuki K, Takita A, Iwashita M, Yamaguchi T Tags: J Cardiol Source Type: research

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