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Condition: Thrombosis
Infectious Disease: Coronavirus

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Total 429 results found since Jan 2013.

COVID-19 and Thromboinflammation: Is There a Role for Statins?
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research

Assistance and health care provided to adolescents with chronic and immunosuppressive conditions in a tertiary university hospital during the COVID-19 pandemic
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research

Post-coronavirus disease syndrome and disseminated microthrombosis: the role of the von Willebrand factor and antiphospholipid antibodies
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research

Neurologic Emergencies during the Coronavirus Disease 2019 Pandemic
Although minor neurologic complications of coronavirus disease 2019 are common, life-threatening neurologic emergencies are rare. Acute ischemic stroke, intracerebral hemorrhage, venous sinus thrombosis, seizures, and posterior reversible encephalopathy syndrome have been described. Hospitals have seen significant changes in the volume of patients presenting with neurologic emergencies. We review what has thus far been published about the intersection of coronavirus disease 2019 and neurologic emergencies with particular attention to cerebrovascular disease and seizure. Considerations in managing the acute presentations of...
Source: Neurologic Clinics - March 26, 2021 Category: Neurology Authors: Julie G. Shulman, Thomas Ford, Anna M. Cervantes-Arslanian Source Type: research

Intestinal Ischemic Manifestations of COVID-19
We read with interest the article by Norsa et  al1 on intestinal ischemia in patients with coronavirus disease 2019 (COVID-19). They further highlight the coagulopathy known to cause vascular obstructions in patients with severe COVID-19, in whom microthrombi are typically found in the lung circulation; however, also myocardial infarction and ischemic stroke were reported, particularly in the late phase of the disease. The patients reported by Norsa et al had either small or large bowel ischemia, splenic infarct, or pulmonary thromboembolism, which were fatal in 4 of the 7 cases.
Source: Gastroenterology - December 29, 2020 Category: Gastroenterology Authors: Antonio Ponzetto, John Holton, Massimo Porta Tags: Correspondence Source Type: research

What you should do if you’ve received the Johnson & Johnson coronavirus vaccine
Six women who had the vaccine suffered from cerebral venous sinus thrombosis, a rare form of stroke. Here’s what to know about symptoms of blood clots if you received the vaccine.
Source: Washington Post: To Your Health - April 13, 2021 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news

Cardiovascular and Cerebrovascular Complications With COVID-19
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 has affected the health of people across the globe. Cardiovascular diseases (CVDs) have a significant relationship with COVID-19, both as a risk factor and prognostic indicator, and as a complication of the disease itself. In addition to predisposing to CVD complications, the ongoing pandemic has severely affected the delivery of timely and appropriate care for cardiovascular conditions resulting in increased mortality. The etiology behind the cardiac injury associated with severe acute respiratory syndrome coronavirus-2 i...
Source: Cardiology in Review - April 17, 2021 Category: Cardiology Tags: Review Articles Source Type: research

Viruses, Vol. 13, Pages 700: Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms
id J Alzahrani Aristóteles Góes-Neto Vasco Azevedo Preetam Ghosh Debmalya Barh The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-term care of COVID-19 survivors. It is thus imperative to study post-COVID (i.e., short-term) and long-COVID (i.e., long-term) effects, specifically as local and systemic pathophysiological outcomes of other coronavirus-related diseases (such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS)) were well-cataloged. We conducted a comprehensive review of adverse post-COVID health outcomes and potential long-COV...
Source: Viruses - April 18, 2021 Category: Virology Authors: Bruno Silva Silva Andrade S érgio Siqueira Wagner Rodrigues de Assis de Assis Soares Fernanda de Souza de Souza Rangel Naiane Oliveira Santos Andria dos Santos dos Santos Freitas Priscila Ribeiro da Ribeiro da Silveira Sandeep Tiwari Khalid J Alzahrani A Tags: Review Source Type: research

Risk factors for intracerebral hemorrhage in patients with COVID-19
AbstractIntracerebral hemorrhage (ICH) can be a devastating complication of coronavirus disease (COVID-19). We aimed to assess risk factors associated with ICH in this population. We performed a retrospective cohort study of adult patients admitted to NYU Langone Health system between March 1 and April 27 2020 with a positive nasopharyngeal swab polymerase chain reaction test result and presence of primary nontraumatic intracranial hemorrhage or hemorrhagic conversion of ischemic stroke on neuroimaging. Patients with intracranial procedures, malignancy, or vascular malformation were excluded. We used regression models to e...
Source: Journal of Thrombosis and Thrombolysis - April 29, 2021 Category: Hematology Source Type: research

Arterial Thrombotic Sequalae After Covid-19: Mind The Gap
Investigations have shown that infection from the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) is responsible also for initiating severe inflammatory responses that can lead macrovascular and microvascular thrombosis.Several studies have already described acute limb ischemia and peripheral arterial disease in critically ill patients with Coronavirus disease 2019 (Covid-19), as well as coronary artery disease and ischemic stroke as a manifestation usually associated with respiratory distress.
Source: Annals of Vascular Surgery - April 30, 2021 Category: Surgery Authors: Maria Pia Borrelli, Adelaide Buora, Paola Scrivere, Massimo Sponza, Paolo Frigatti Source Type: research

COVID ‐19 Outcomes in Patients With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A US Multicenter, Comparative Cohort Study
ConclusionOur findings indicate that COVID ‐19 patients with systemic ARDs may be at a higher risk of hospitalization, ICU admission, acute renal failure, and venous thromboembolism when compared to COVID‐19 patients without systemic ARDs. These risks may be largely mediated by comorbidities, except for the risk of venous thromboembolism .
Source: Arthritis and Rheumatology - May 1, 2021 Category: Rheumatology Authors: Kristin M. D ’Silva, April Jorge, Andrew Cohen, Natalie McCormick, Yuqing Zhang, Zachary S. Wallace, Hyon K. Choi Tags: Brief Report Source Type: research

Cerebral venous thrombosis following COVID-19 vaccination
We appreciate the literature review by Abdalkader et al.1 to summarize the clinical epidemiology and features of cerebral venous thrombosis (CVT) in patients with coronavirus disease 2019 (COVID-19). Based on the meta-analysis performed by Baldini et al.,2 the estimated proportion of CVT cases among hospitalized patients with COVID-19 was 0.08%; therefore, it is not surprising that COVID-19 associated CVT had not been given much attention compared to the more common deep vein thrombosis and pulmonary embolism events in this patient population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2021 Category: Neurology Authors: Chia Siang Kow, Syed Shahzad Hasan Tags: Letter to the Editor Source Type: research

A Review of Pathophysiology, Clinical Features, and Management Options of COVID-19 Associated Coagulopathy
There is increasing evidence that novel coronavirus disease 2019 (COVID-19) leads to a significant coagulopathy, a phenomenon termed “COVID-19 associated coagulopathy.” COVID-19 has been associated with increased rates of both venous and arterial thromboembolic events, a source of significant morbidity and mortality in this disease. Further evidence suggests a link between the inflammatory response and coagulopathy associated with COVID-19. This presents a unique set of challenges for diagnosis, prevention, and treatment of thrombotic complications. In this review, we summarize and discuss the current literature on lab...
Source: Shock - May 27, 2021 Category: Emergency Medicine Tags: Review Articles Source Type: research

Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets
Platelets. 2021 Jun 7:1-9. doi: 10.1080/09537104.2021.1936478. Online ahead of print.ABSTRACTPlatelets may be a target of bacteria and viruses, which can directly or indirectly activate them so promoting thrombosis. In accordance with this, community-acquired pneumonia (CAP) is complicated by ischemia-related vascular disease (myocardial infarction and stroke) in roughly 10% of patients while the incidence of venous thrombosis is uncertain. In CAP platelet biosynthesis of TxA2 is augmented and associated with myocardial infarction; however, a cause-effect relationship is still unclear as unclear is if platelet activation p...
Source: Platelets - June 7, 2021 Category: Hematology Authors: Francesco Violi Vittoria Cammisotto Pasquale Pignatelli Source Type: research

Interaction between thrombin potential and age on early clinical outcome in patients hospitalized for COVID-19
AbstractPatients with Coronavirus Disease-2019 (COVID ‐19) have haemostatic dysfunction and are at higher risk of thrombotic complications. Although age is a major risk factor for outcome impairment in COVID-19, its impact on coagulative patterns here is still unclear. We investigated the association of Endogenous Thrombin Potential (ETP) with thromb otic and haemorrhagic events according to different ages in patients admitted for COVID-19. A total of 27 patients with COVID‐19-related pneumonia, without need for intensive care unit admission or mechanical ventilation at hospital presentation, and 24 controls with non-C...
Source: Journal of Thrombosis and Thrombolysis - June 10, 2021 Category: Hematology Source Type: research