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Condition: Vasculitis

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Total 771 results found since Jan 2013.

Unilateral Intracranial Arteriopathy in Pediatric Stroke: Course, Outcome, and Prediction of Reversible Arteriopathy Brief Reports
Conclusions— The possibility of reversible arteriopathy should be suspected in children and adolescents presenting with arterial ischemic stroke and unilateral arteriopathy.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Yeon, J. Y., Shin, H. J., Seol, H. J., Kim, J.-S., Hong, S.-C. Tags: Stroke in Children and the Young, Other Stroke Treatment - Medical, Vasculitis Brain Arteries Brief Reports Source Type: research

Stroke in the Young: Etiologies and Risk Factors (P7.124)
CONCLUSIONS: Stroke in the young shares many of the same common modifiable risk factors as stroke in the elderly including hypertension, hyperlipidemia, diabetes, and tobacco abuse. Other unique disease processes also contribute to stroke in this age group, often less modifiable. Given the devastating morbidity and mortality of stroke in this age group, a larger public health effort for primary and secondary prevention of stroke in the young should be aggressively pursued.Disclosure: Dr. Govind has nothing to disclose. Dr. Ahad has nothing to disclose. Dr. Iftekhar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Govind, P., Ahad, R., Iftekhar, A. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Stroke associated with giant cell arteritis: a population-based study
Conclusions This population-based study demonstrated that GCA-related stroke essentially affects the vertebrobasilar territory and mainly occurs in old men with associated vascular risk factors. Although rare, GCA symptoms must be searched for in elderly patients with stroke, and optimal vascular prevention must be conducted carefully in patients with GCA with a high vascular risk before initiating GCA treatment.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2015 Category: Neurosurgery Authors: Samson, M., Jacquin, A., Audia, S., Daubail, B., Devilliers, H., Petrella, T., Martin, L., Durier, J., Besancenot, J.-F., Lorcerie, B., Giroud, M., Bonnotte, B., Bejot, Y. Tags: Immunology (including allergy), Stroke, Vascularitis Cerebrovascular disease Source Type: research

TNF-Blockade for Primary Stroke Prevention in Adenosine Deaminase 2 Deficiency: A Case Series
We present a family with multiple affected children to highlight the importance of TNF blockade not just as secondary stroke prevention but also as primary stroke prevention in genetically affected but clinically asymptomatic patients. Methods A proband with recurrent cryptogenic strokes was referred for evaluation at the NIH CC. The parents and 3 clinically asymptomatic siblings were also evaluated. Results The proband was diagnosed with DADA2 based on biochemical testing; her antiplatelet therapies were discontinued, and she was started on TNF blockade for secondary stroke prevention. Her 3 asymptomatic siblings were s...
Source: Neurology Neuroimmunology and Neuroinflammation - March 20, 2023 Category: Neurology Authors: Soldatos, A., Toro, C., Hoffmann, P., Romeo, T., Deuitch, N., Brofferio, A., Aksentijevich, I., Kastner, D. L., Ombrello, A. K. Tags: Childhood stroke, Stroke in young adults, Stroke prevention, Vasculitis, All Genetics Clinical/Scientific Note Source Type: research

Cadagan: Humor and tenacity after a stroke
Most parents try to discourage their children from indulging in humor about bodily functions like burping. But for Daniel and Lori Hooley, a simple smirk in response to a belch was the sign they needed that their daughter, Cadagan, was going to be okay. It was 2012 and 7-year-old Cadagan was asleep, tucked into bed for the night. Around 11 p.m., she suddenly awoke — but it wasn’t because of a nightmare or a late-night request for a glass of water. Instead, she seemed limp and couldn’t focus. Then she began throwing up. Born with an extremely rare genetic disorder called trisomy 12p, the little girl had already experi...
Source: Thrive, Children's Hospital Boston - November 20, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Cameron Trenor Dr. Laura Lehman Dr. Michael Rivkin stroke Stroke and Cerebrovascular Center vasculitis Source Type: news

Moyamoya Disease in Children: Results of the International Pediatric Stroke Study (S55.001)
Conclusions: The definition of MMD is variable, and may influence reported outcomes. The presence of additional stroke risk factors in over half of patients implies a multifactorial etiology. Our data suggest that vascular occlusion contributes to recurrence, and may be an important predictor in this population.Disclosure: Dr. Lee has nothing to disclose. Dr. Rivkin has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. DeVeber has nothing to disclose. Dr. Elbers has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lee, S., Rivkin, M., Kirton, A., DeVeber, G., Elbers, J. Tags: Pediatric Stroke and Stroke in the Young Source Type: research

Prevalence of stenoses and occlusions of brain-supplying arteries in young stroke patients
Conclusions: We observed a substantial proportion of atherosclerotic carotid artery stenoses and occlusions in younger stroke patients. Intracranial stenoses and occlusions were even more prevalent than extracranial carotid artery disease. Together with nonstenotic plaques, one-fifth of patients (21.2%) had symptomatic or asymptomatic large-artery atherosclerosis, which should encourage future stroke prevention campaigns to target risk factor modification in young people.
Source: Neurology - April 1, 2013 Category: Neurology Authors: von Sarnowski, B., Schminke, U., Tatlisumak, T., Putaala, J., Grittner, U., Kaps, M., Tobin, W. O., Kinsella, J. A., McCabe, D. J. H., Hennerici, M. G., Fazekas, F., Norrving, B., Kessler, C., Rolfs, A., On behalf of the sifap1 investigators Tags: Stroke in young adults, Ultrasound, Prevalence studies, Risk factors in epidemiology ARTICLE Source Type: research

Young-aged stroke in Korea: changing patterns of risk factors and etiologies (P7.120)
CONCLUSIONS: Compared to the previous study, the proportion of male to female ratio decreased. While smoking and drinking rates decreased in male, metabolic risk factors such as diabetes and dyslipidemia increased in both genders, which explain the increasing proportion of large artery atherosclerotic disease in female patients. The proportion of strokes associated with artery dissection increased, which may be due to the use of advanced diagnostic tools. Our data show that etiologies in young age strokes change depending on the changing risk factor profiles and extensiveness of advanced diagnostic work up.Disclosure: Dr. ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kim, H. A., Kim, J., Kim, B. J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Primary Angiitis of the Central Nervous System Clinical Sciences
Conclusions—Adult primary angiitis of the central nervous system is a heterogenous disease, with multiterritorial, distal, and bilateral acute stroke being the most common pattern of parenchymal lesions found on magnetic resonance imaging. Our findings suggest a higher than previously thought prevalence of hemorrhagic transformation and other hemorrhagic manifestations.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Gregoire Boulouis, Hubert de Boysson, Mathieu Zuber, Loic Guillevin, Eric Meary, Vincent Costalat, Christian Pagnoux, Olivier Naggara Tags: Imaging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Unlabeled amphetamine isomer in sports supplement “probably” caused hemorrhagic stroke
3.5 out of 5 stars Hemorrhagic Stroke Probably Caused by Exercise Combined With a Sports Supplement Containing β-Methylphenylethylamine (BMPEA): A Case Report. Cohen P et al. Ann Intern Med 2015 May 12 [Epub ahead of print] Reference Last month, the FDA sent letters to 5 companies that manufacture so-called “dietary” or “sports” supplements, warning them that their products were mislabeled because they contained an unlisted ingredient. That ingredient, β-methylphenylethylamine (BMPEA), is an isomer of amphetamine. Although the effects of BMPEA in humans have not been well studied, it has been ...
Source: The Poison Review - May 22, 2015 Category: Toxicology Authors: Leon Tags: Medical amphetamine beta-methylphenylethylamine BMPEA dietary supplement hemorrhagic stroke sports supplement Source Type: news

Intracranial Vessel Wall MRI in Cryptogenic Stroke and Intracranial Vasculitis
Introduction: Intracranial vasculopathies easily elude classic stroke work-up. We aim in this work to show that vessel wall-MRI could prove an efficient alternative to digital subtraction angiography for the diagnosis of intracranial vasculopathies by identifying intracranial arterial vessel walls anomalies and contrast enhancement, suggestive of angiitis of the central nervous system. Materials and methods: Clinical and imaging characteristics of stroke patients diagnosed with primary angiitis of the central nervous system based on vessel wall-MRI were retrospectively reviewed and the clinical and imaging features of angi...
Source: Journal of Stroke and Cerebrovascular Diseases - March 5, 2020 Category: Neurology Authors: Virginie Destrebecq, Niloufar Sadeghi, Boris Lubicz, Lise Jodaitis, Noemie Ligot, Gilles Naeije Source Type: research

Lateral Medullary Stroke in Patient with Granulomatous Polyangiitis
We report a 41-year-old man with lateral medullary infarction who developed rapidly progressive renal failure. He was diagnosed with GPA based on positive serum c-ANCA and antiproteinase 3 antibodies and demonstration of pauci-immune crescentic glomerulonephritis on kidney biopsy. He was treated with Coumadin, pulse steroids, cyclophosphamide, and plasmapheresis. He had resolution of his neurologic deficits and improvement in renal function. This case report highlights the importance to consider GPA vasculitis in the differential diagnosis of stroke in patients with development of acute kidney injury.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2013 Category: Neurology Authors: Olga D. Taraschenko, Colum F. Amory, Jonathan Waldman, Era K. Hanspal, Gary L. Bernardini Tags: Case Reports Source Type: research

Challenge of Identifying the Cause of Intracranial Artery Stenosis in Patients With Ischemic Stroke Illustrative Teaching Case
Source: Stroke - February 23, 2015 Category: Neurology Authors: Lanthier, S., Odier, C., Sundararajan, S., Strbian, D. Tags: Secondary prevention, Other arteriosclerosis, Other diagnostic testing, Stroke in Children and the Young, Vasculitis Brain Arteries Illustrative Teaching Case Source Type: research

Case Report: Giant Cell Arteritis-Related Stroke
Thromboembolic events are major contributors to the morbidity and mortality of patients with giant cell arteritis (GCA), but little is known about how GCA may increase the risk of ischemic strokes. GCA-related stroke is described as an ischemic cerebral infarct occurring within three to four weeks of GCA diagnosis and treatment. It occurs in 3–7%... [Read More]
Source: The Rheumatologist - September 10, 2023 Category: Rheumatology Authors: Jessica Meek, MD, Anna Coppinger, DO, & Sejal Khan, DO Tags: Conditions Home Slider Vasculitis case report GCA giant cell arteritis (GCA) stroke Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research