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Condition: Multiple Sclerosis
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Total 1656 results found since Jan 2013.
Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition
CONCLUSION: Our results suggest that Tregs promote functional recovery after SCI by alleviating microglia inflammatory reaction via STAT3.PMID:36914969 | DOI:10.1111/cns.14161
Source: CNS Neuroscience and Therapeutics - March 14, 2023 Category: Neuroscience Authors: Rui Liu Ying Li Ziyue Wang Peng Chen Yi Xie Wensheng Qu Minghuan Wang Zhiyuan Yu Xiang Luo Source Type: research
The effect of statins on the differentiation and function of central nervous system cells
Curr Med Chem. 2023 Mar 8. doi: 10.2174/0929867330666230308121645. Online ahead of print.ABSTRACTStatins (3-hydroxy-3-methylglutaryl-CoA reductase inhibitors) reduce plasma cholesterol and improve endothelium-dependent vasodilation, inflammation, and oxidative stress. The effect of statins on the central nervous system (CNS), particularly on cognition and neurological disorders such as cerebral ischemic stroke, multiple sclerosis (MS), and Alzheimer's disease (AD), has received increasing attention in recent years, both within the scientific community and in the media. This review aims to provide an updated discussion on t...
Source: Current Medicinal Chemistry - March 9, 2023 Category: Chemistry Authors: Sajjad Chamani Leila Mobasheri Shadi Zerehpoosh Ali Naghizadeh Alice P McCloskey Manfredi Rizzo Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research
Good multiple sclerosis (MS) care and how to get there in Canada: Perspectives of Canadian healthcare providers working with persons with MS
ConclusionTo meet the care needs of Canadians with MS, the healthcare system must consider standardizing and funding multidisciplinary team-based MS clinics, comparable to Stroke units, which continue to show favorable health outcomes after years of implementation.
Source: Frontiers in Neurology - March 2, 2023 Category: Neurology Source Type: research
Inflammatory Bowel Disease and Neurodegenerative Diseases
Gut Liver. 2023 Feb 27. doi: 10.5009/gnl220523. Online ahead of print.ABSTRACTA growing body of evidence has demonstrated an intricate association between inflammatory bowel disease (IBD) and neurodegenerative conditions, expanding beyond previous foci of comorbidities between IBD and mood disorders. These new discoveries stem from an improved understanding of the gut-microbiome-brain axis: specifically, the ability of the intestinal microbiota to modulate inflammation and regulate neuromodulatory compounds. Clinical retrospective studies incorporating large sample sizes and population-based cohorts have demonstrated and c...
Source: Gut and Liver - February 27, 2023 Category: Gastroenterology Authors: Jin Sun Kim Mu-Hong Chen Hohui E Wang Ching-Liang Lu Yen-Po Wang Bing Zhang Source Type: research
Dietary energy restriction in neurological diseases: what’s new?
AbstractEnergy-restricted diet is a specific dietary regimen, including the continuous energy-restricted diet and the intermittent energy-restricted diet. It has been proven effective not only to reduce weight and extend the lifespan in animal models, but also to regulate the development and progression of various neurological diseases such as epilepsy, cerebrovascular diseases (stroke), neurodegenerative disorders (Alzheimer's disease and Parkinson's disease) and autoimmune diseases (multiple sclerosis). However, the mechanism in this field is still not clear and a systematic neurological summary is still missing. In this...
Source: European Journal of Nutrition - February 26, 2023 Category: Nutrition Source Type: research
Alternative medicine therapies in neurological disorders: Prevalence, reasons and associated factors. A systematic review
CONCLUSIONS: The prevalence of CAM use in neurological diseases is highly variable (16%-100%); the most used type of CAM was biological therapies and the associated factors were female sex, age between 40 and 50 years old and high socioeconomic level.PMID:36805318 | DOI:10.1016/j.ctim.2023.102932
Source: Complementary Therapies in Medicine - February 22, 2023 Category: Complementary Medicine Authors: Mar ía Soto-Lara Melissa Silva-Loredo Jos é Rodrigo Monroy-Córdoba Paola Flores-Ordo ñez Nelly G Cervera-Delgadillo Paul Carrillo-Mora Source Type: research
Dietary energy restriction in neurological diseases: what’s new?
AbstractEnergy-restricted diet is a specific dietary regimen, including the continuous energy-restricted diet and the intermittent energy-restricted diet. It has been proven effective not only to reduce weight and extend the lifespan in animal models, but also to regulate the development and progression of various neurological diseases such as epilepsy, cerebrovascular diseases (stroke), neurodegenerative disorders (Alzheimer's disease and Parkinson's disease) and autoimmune diseases (multiple sclerosis). However, the mechanism in this field is still not clear and a systematic neurological summary is still missing. In this...
Source: European Journal of Nutrition - February 21, 2023 Category: Nutrition Source Type: research
Fatigue and its relation to general cognition, social cognition and social activity in multiple sclerosis and stroke
CONCLUSIONS: Future studies ought to further explore the potentially complex nature of fatigue symptoms and their relationship with (socio-)cognitive performance and social activity in neurological populations.PMID:36782396 | DOI:10.1080/13546805.2023.2178399
Source: Cognitive Neuropsychiatry - February 14, 2023 Category: Psychiatry Authors: Tobias Lohaus Judith Witt Anne Sch ürmeyer Oliver T Wolf Patrizia Thoma Source Type: research
