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Condition: Multiple Sclerosis

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Total 1656 results found since Jan 2013.

Fatigue and its relation to general cognition, social cognition and social activity in multiple sclerosis and stroke
CONCLUSIONS: Future studies ought to further explore the potentially complex nature of fatigue symptoms and their relationship with (socio-)cognitive performance and social activity in neurological populations.PMID:36782396 | DOI:10.1080/13546805.2023.2178399
Source: Cognitive Neuropsychiatry - February 14, 2023 Category: Psychiatry Authors: Tobias Lohaus Judith Witt Anne Sch ürmeyer Oliver T Wolf Patrizia Thoma Source Type: research

Sphingosine-1-phosphate Signalling in Aneurysmal Subarachnoid Haemorrhage: Basic Science to Clinical Translation
AbstractSphingosine-1-phosphate (S1P) is generated intracellularly and, when transported to the extracellular compartment, predominantly signals through S1P receptors. The S1P signalling pathway has been implicated in the pathophysiology of neurological injury following aneurysmal subarachnoid haemorrhage (aSAH). In this review, we bring together all the available data regarding the role of S1P in neurological injury following aSAH. There is agreement in the literature that S1P increases in the cerebrospinal fluid following aSAH and leads to cerebral artery vasospasm. On the other hand, the role of S1P in the parenchyma is...
Source: Translational Stroke Research - February 7, 2023 Category: Neurology Source Type: research

A view of care pathways approved by Italian Regions, to face the challenge of the community-based healthcare: a quali-quantitative analysis of the Pdta Net database.
CONCLUSIONS: The high number of CPs approved in Italy confirms an increasing interest of the healthcare institutions. The collected CPs show an extreme variety of titles, text structures and disease choices. Given the absence of an institutional observatory and of devotees of shared and harmonized CPs, annually Pdta Net makes available an updated and complete overview of these governance tools, which are essential for the upcoming changes of the Italian national health service.PMID:36573531 | DOI:10.1701/3939.39228
Source: Cancer Control - December 27, 2022 Category: Cancer & Oncology Authors: Irene Dell'Anno Silvia Calabria Letizia Dondi Giulia Ronconi Leonardo Dondi Alice Addesi Antonella Pedrini Immacolata Esposito Aldo Pietro Maggioni Nello Martini Carlo Piccinni Source Type: research

A scoping review to identify process and outcome measures used in acceptance and commitment therapy research, with adults with acquired neurological conditions
CONCLUSIONS: This study provides a resource to support future identification of candidate measures. This could aid development of a Core Outcome Set to support both research and clinical practice. Further research to identify the most appropriate and relevant targets and tools for use in these populations should include expert consensus, patient, carer and public involvement and psychometric examination of measures.PMID:36540937 | DOI:10.1177/02692155221144554
Source: Clinical Rehabilitation - December 21, 2022 Category: Rehabilitation Authors: Hannah Foote Audrey Bowen Sarah Cotterill Geoff Hill Matilde Pieri Emma Patchwood Source Type: research

The importance of neuromuscular rate of force development for physical function in aging and common neurodegenerative disorders - a systematic review
J Musculoskelet Neuronal Interact. 2022 Dec 1;22(4):562-586.ABSTRACTWe systematically reviewed existing literature regarding lower extremity neuromuscular rate of force development (RFD), maximal muscle strength (Fmax), and physical function in neurodegenerative populations, and to what extent these outcomes are affected and/or associated. Following PRISMA guidelines, 4 databases (Pubmed, Embase, SPORTDiscus, Web of Science) were searched. Across aging, Parkinson Disease (PD), Alzheimer's Disease (AD), Multiple Sclerosis (MS), or Stroke, included studies should report (Part 1) deficits in lower extremity RFD, Fmax, and phy...
Source: Journal of Musculoskeletal Neuronal Interactions - December 2, 2022 Category: Neurology Authors: Sidsel D Lomborg Ulrik Dalgas Lars G Hvid Source Type: research