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Condition: Hemorrhagic Stroke
Procedure: Gastroschisis Repair

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Total 192 results found since Jan 2013.

Open Repair of Acute Type A Intramural Hematoma in 3 Patients
Tex Heart Inst J. 2020 Aug 1;47(4):290-297. doi: 10.14503/THIJ-20-7242.ABSTRACTAcute aortic syndrome encompasses classic aortic dissection and less common aortic phenomena, including intramural hematoma (IMH), a hemorrhage within the aortic media that occurs without a discrete intimal tear. We reviewed our experience with treating acute type A IMH to better understand this acute aortic syndrome. A review of our clinical database identified 1,902 proximal aortic repairs that were performed from January 2006 through December 2018; of these, 266 were for acute aortic syndrome, including 3 (1.1%) for acute type A IMH. Operativ...
Source: Texas Heart Institute Journal - January 20, 2021 Category: Cardiology Authors: William C Frankel Scott A Weldon Susan Y Green Hiruni S Amarasekara Scott A LeMaire Joseph S Coselli Source Type: research

BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF- κB Pathway During ICH Recovery
Intracerebral hemorrhage (ICH) is a life-threatening type of stroke that lacks effective treatments. The inflammatory response following ICH is a vital response that affects brain repair and organism recovery. The nuclear factor κB (NF-κB) signaling pathway is considered one of the most important inflammatory response pathways and one of its response pathways, the noncanonical NF-κB signaling pathway, is known to be associated with persistent effect and chronic inflammation. NF-κB–inducing kinase (NIK) via the noncanonical NF-κB signaling plays a key role in controlling inflammation. Here, we investigated potential ...
Source: Frontiers in Pharmacology - May 7, 2021 Category: Drugs & Pharmacology Source Type: research

Midterm Outcomes of a Prospective, Nonrandomized Study to Evaluate Endovascular Repair of Complex Aortic Aneurysms Using Fenestrated-Branched Endografts
Conclusion: FB-EVAR is safe and effective for treatment of PRA and TAAAs with low rate of aortic-related mortality and aneurysm rupture on midterm follow-up.
Source: Annals of Surgery - August 20, 2021 Category: Surgery Tags: PAPERS OF THE 141ST ASA ANNUAL MEETING Source Type: research

Molecular Correlates of Hemorrhage and Edema Volumes Following Human Intracerebral Hemorrhage Implicate Inflammation, Autophagy, mRNA Splicing, and T Cell Receptor Signaling
This study uncovers molecular underpinnings associated with ICH and PHE vo lumes and pathophysiology in human ICH, where knowledge is scarce. The identified pathways and hub genes may represent novel therapeutic targets.
Source: Translational Stroke Research - September 6, 2021 Category: Neurology Source Type: research

GrpEL1 Regulates Mitochondrial Unfolded Protein Response after Experimental Subarachnoid Hemorrhage in vivo and in vitro
In conclusion, the reduced GrpEL1-mtHSP70 complex is an essential factor affecting UPRmt in EBI after SAH. Increasing GrpEL1 promotes GrpEL1 and mtHSP70 binding, promoting the neuronal mitochondrial homeostasis, and might be an essential clinical intervention target for EBI after SAH.PMID:35093469 | DOI:10.1016/j.brainresbull.2022.01.014
Source: Brain Research Bulletin - January 30, 2022 Category: Neurology Authors: Chao Ma Bixi Gao Zongqi Wang Wanchun You Zhengquan Yu Haitao Shen Xiang Li Haiying Li Xuwei Zhang Zhong Wang Gang Chen Source Type: research

Role of Dexmedetomidine in Aneurysmal Subarachnoid Hemorrhage: A Comprehensive Scoping Review
Dexmedetomidine (DEX), an α2-adrenergic agonist, has been widely used for anesthesia, pain control, and intensive care unit sedation. Besides sleep-like sedation, DEX has many other beneficial effects, such as anti-inflammation, antioxidation, and anticell death. Subarachnoid hemorrhage (SAH), a severe and potentially fatal form of stroke, is a complex disease that is divided into 2 phases: early brain injury and delayed cerebral ischemia. In each phase, several pathologic changes are involved, including disturbed intracranial homeostasis, metabolic failure, blood-brain barrier damage, vasospasm, microthrombosis, and cort...
Source: Journal of Neurosurgical Anesthesiology - March 15, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

A Comparison of Outcomes Using Combined Intra- and Extradural versus Extradural-Only Repair of Tegmen Defects
Conclusion The results of this study suggest no difference in clinical outcomes between combined intra-/extradural versus extradural-only repair of tegmen defects. A simplified extradural-only repair strategy can be effective, and may reduce the morbidity of intradural reconstruction (seizures, stroke, and intraparenchymal hemorrhage). [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part B: Skull Base - February 1, 2022 Category: Neurosurgery Authors: Khanna, Omaditya D'Souza, Glen Hattar-Medina, Ellina Karsy, Michael Chiffer, Rebecca C. Willcox, Thomas O. Farrell, Christopher J. Evans, James J. Tags: Original Article Source Type: research

Renal cyst mimicking hydronephrosis after uterine artery ligation for postpartum haemorrhage
Conclusion: Renal cyst is a differential diagnosis of hydronephrosis. Delayed availability of the final result of medical investigations jeopardises patients ’ safety. A preliminary imaging report is prone to error and its use to determine the indication for an invasive procedure should be limited to emergencies.Keywords: Uterine artery ligation; preliminary imaging report; ureteric injury.
Source: African Health Sciences - August 1, 2022 Category: African Health Authors: Nnabuike Chibuoke Ngene Source Type: research

Activation of HIF-1α/VEGF-A pathway by deferoxamine ameliorates retinal hypoxia in a rat subarachnoid hemorrhage model
Conclusions Our findings suggest that modulating the application of deferoxamine may offer therapeutic approaches to alleviate retinal complications after SAH.
Source: NeuroReport - October 6, 2022 Category: Neurology Tags: Degeneration and Repair Source Type: research

Semaphorin 6D regulate corralling, hematoma compaction and white matter injury in mice after intracerebral hemorrhage
The Semaphorin 6D (SEMA6D) shows important roles in cell guidance and lipid metabolism, but the effects and mechanisms of SEMA6D on tissue repair, white matter injury and the recovery of neurological function after intracerebral hemorrhage have not been well studied.
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2022 Category: Neurology Authors: Ting Sun, Hanhai Zeng, Linfeng Fan, Jing Fei, Gao Chen Source Type: research

Protect That Neck! Management of Blunt and Penetrating Neck Trauma
Blunt and penetrating vascular injuries to the neck represent a significant burden of mortality and disability among trauma patients. Blunt cerebrovascular injury can present with signs of stroke either immediately or in a delayed fashion. Most injuries are detected with computed tomography angiogram and managed by antiplatelet agents or unfractionated heparin. In contrast, for patients presenting with penetrating neck injuries, assessment for hard signs of vascular and aerodigestive injury should be done and prompt emergent surgical consultation if present. Overall management priorities for penetrating neck injuries focus...
Source: Emergency Medicine Clinics of North America - November 22, 2022 Category: Emergency Medicine Authors: Matt Piaseczny, Julie La, Tim Chaplin, Chris Evans Source Type: research