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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hemorrhagic Stroke
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Total 1025 results found since Jan 2013.
The Burden of Diabetes and the Chance of a Previous Stroke: Thrombolysis for Recurrent Stroke in Diabetics
Intravenous thrombolysis with recombinant tissue plasminogen activator is still not approved by the European Medicines Agency for patients with diabetes mellitus and previous stroke. We assessed functional benefit and potential risk of thrombolysis in patients with diabetes and previous stroke and the influence of age, preexisting diabetic damage, as well as acute and chronic hyperglycemia on outcome, symptomatic intracranial hemorrhage, and in-hospital mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2018 Category: Neurology Authors: Alexandra Filipov, Anne D. Ebert, Eva Neumaier-Probst, Angelika Alonso Source Type: research
Thrombolysis in Ischemic Stroke Patients with Isolate Pulmonary Arteriovenous Malformations
Pulmonary arteriovenous malformations are rare cause for ischemic stroke. British Thoracic Society Clinical Statement considered insufficient evidence of safety or clinical benefit to recommend thrombolysis for stroke with pulmonary arteriovenous malformations. For pulmonary arteriovenous malformations with hereditary hemorrhagic telangiectasia, bleeding risk after thrombolysis is high, while for isolate pulmonary arteriovenous malformations, bleeding risk is much lower. We here present 2 cases of ischemic stroke with isolate pulmonary arteriovenous malformations treated with thrombolysis.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2019 Category: Neurology Authors: Gaoping Lin, Peng Jiang, Min Lou Tags: Case Report Source Type: research
Factors Associated with Leukoaraiosis Severity in Acute Stroke Patients
Objective: Age-related cerebral white matter abnormalities, commonly termed leukoaraiosis (LA), are frequent manifestation of cerebral microvascular disease. Aging and hypertension are well linked to LA. We compared additional vascular risk factors and socioeconomic factors with LA severity in acute stroke patients. Methods: We analyzed 271 patients with acute ischemic or hemorrhagic stroke from a hospital registry. We collected clinical and socioeconomic data prospectively with a standardized questionnaire during acute stroke hospitalization.
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2019 Category: Neurology Authors: Kishore Vedala, Arun K. Nagabandi, Stephen Looney, Askiel Bruno Source Type: research
Urban Versus Rural Egypt: Stroke Risk Factors and Clinical Profile: Cross-Sectional Observational Study
Background: Egypt is a densely populated country with living habits and health care services that differ from urban to rural regions. We aimed to study how characteristics of stroke vary among these regions. Methods: This is a cross-sectional observational study of ischemic stroke, thus hemorrhagic and venous strokes were excluded. A total of 1475 ischemic stroke patients were recruited for analysis from a tertiary hospital in Cairo representing urban area and from a secondary care hospital in Suhag representing rural region.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2019 Category: Neurology Authors: Nevine M. El Nahas, Hossam M. Shokri, Tamer M. Roushdy, Hany M. Aref, Salma M. Hamed, Ali S. Shalash, Mohamed I. Abdelrahem, Noha L. Dawood, Eman M. Abushady, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros Source Type: research
Cerebral Microbleeds and Chronic Kidney Disease in Acute Ischemic Stroke Patients with Atrial Fibrillation
Background: Cerebral microbleeds (CMBs) are associated with the risk of intracerebral hemorrhage in stroke patients with atrial fibrillation (AF). We investigated the association between CMBs and chronic kidney disease (CKD) in patients with acute ischemic stroke and AF. Methods: We retrospectively examined consecutive patients with acute ischemic stroke and AF who underwent brain gradient-echo T2*-weighted magnetic resonance imaging. The number and distribution (lobar, deep or infratentorial, and mixed) of CMBs were assessed.
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2020 Category: Neurology Authors: Kazuo Yamashiro, Ryota Tanaka, Naohide Kurita, Yuji Ueno, Nobukazu Miyamoto, Kenichiro Hira, Sho Nakajima, Takao Urabe, Nobutaka Hattori Source Type: research
Hemorrhagic stroke associated with essential thrombocythemia: Case report and literature review
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by the overproduction of circulating platelets in the peripheral blood, caused by the excessive proliferation of megakaryocytes in the bone marrow.1 Cerebrovascular events, mainly ischemic stroke, are one of the most serious complications in patients with ET, and the V617F mutation in the Janus kinase 2 (JAK2) gene is recognized as a thrombotic risk factor.2 Hemorrhagic stroke associated with ET is very infrequent, and the effect of mutation types on hemorrhagic stroke remains unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Akihiko Momozaki, Jun Masuoka, Takashi Furukawa, Motofumi Koguchi, Hiroshi Ito, Fumitaka Yoshioka, Kohei Inoue, Atsushi Ogata, Yukiko Nakahara, Tatsuya Abe Tags: Case Report Source Type: research
Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome by Sex
Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), usually presents as a respiratory illness. Neurological manifestations can be seen in 36.4% of patients.1 Patients with vascular risk factors (VRFs), including history of stroke, tend to have worse prognosis.2 COVID-19 triggers a robust inflammatory response which leads to hypercoagulability and thromboembolism.3 Reports of stroke in patients with COVID-19 are mostly limited to small case series or case reports of ischemic stroke (IS), though intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) have also been reported.
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2020 Category: Neurology Authors: G. Trifan, F.D. Goldenberg, F.C. Caprio, J. Biller, M. Schneck, A. Khaja, T. Terna, J. Brorson, C. Lazaridis, Z. Bulwa, R. Alvarado-Dyer, F.G. Saleh-Velez, S. Prabhakaran, E.M. Liotta, A. Batra, N.J. Reish, S. Ruland, M. Teitcher, W. Taylor, P. De la Pena Source Type: research
Cerebral Herniation Secondary to Stroke-associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Stephan A. Mayer, Justin Santarelli, Chirag Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research
The Predicting Role of Neutrophil – Lymphocyte Ratio in Patients with Acute Ischemic and Hemorrhagic Stroke
This study evaluated the possible roles of the NLR in estimating mortality rate and health problems in patients with acute ischemic (IS) and hemorrhagic (H) stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2020 Category: Neurology Authors: Reza Daneshvar kakhki, Maryam Dehghanei, Reza ArefNezhad, Hossein Motedayyen Source Type: research
Endovascular Therapy of Acute Ischemic Stroke in Patients with Large-Vessel Occlusion Associated with Active Malignancy
Approximately 15% of cancer patients have concomitant cerebrovascular disease.1,2 The frequency of ischemic and hemorrhagic stroke in this group of patients is similar to the general population2, and about one in ten stroke patients may have a concurrent malignancy.3 Intravenous thrombolysis (IVT) in these patients is often contraindicated and is used less frequently due to various possible comorbidities.4 While EVT is a well-established approach to treat acute ischemic stroke (AIS) secondary to large vessel occlusion (LVO) 5,6,7,8, there is paucity of data with regards to EVT success and outcomes in patients with active malignancy.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2020 Category: Neurology Authors: Tomohiko Ozaki, Patrick Nicholson, Joanna D. Schaafsma, Ronit Agid, Timo Krings, Aleksandra Pikula, Vitor Mendes Pereira Source Type: research
Controversies: Stroke Prevention in Chronic Kidney Disease
Risk of both ischemic and hemorrhagic stroke is increased in the chronic kidney disease (CKD) population, particularly in end-stage kidney disease patients. Uremic factors that contribute to stroke risk include blood pressure variability, vascular calcification, build-up of vascular toxins, chronic inflammation, platelet dysfunction and increased brain microbleeds. This paper discusses the controversial evidence for stroke prevention strategies including blood pressure control, statins, antiplatelet agents, and anticoagulation in the CKD population.
Source: Journal of Stroke and Cerebrovascular Diseases - February 25, 2021 Category: Neurology Authors: Wei Ling Lau Source Type: research
Anticoagulation Protocol for Secondary Prevention of Acute Ischemic Stroke Associated with Nonvalvular Atrial Fibrillation
Atrial fibrillation (AF) is a major risk factor for ischemic stroke and despite evidence for the efficacy of anticoagulation for secondary prevention of recurrent stroke in patients with AF,1 to date there is no established evidence regarding the timing for initiation of oral anticoagulants (OACs), including direct oral anticoagulants (DOACs), for secondary prevention of acute ischemic stroke associated with AF. Of concern in early initiation of OACs is the risk of recurrence balanced with the risk of hemorrhagic transformation (HT) after vascular reperfusion with reports of 3.6% symptomatic cerebral bleeding for acute use of OACs.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Teruo Kimura, Adam Tucker, Atsushi Nakagaki, Toshihide Sugimura, Shin Fukuda, Makoto Katsuno, Tsutomu Fujita, Naoto Izumi, Nozomi Suzuki, Kazuhiro Sako Source Type: research
Gender Disparities in Stroke Code Activation in Patients with Intracerebral Hemorrhage
Routine implementation of protocol-driven stroke “codes” results in timelier and more effective acute stroke management. However, it is unclear if patient demographics contribute to disparities in stroke code activation. We aimed to explore these demographic factors in a retrospective cohort study of patients with intracerebral hemorrhage (ICH ).
Source: Journal of Stroke and Cerebrovascular Diseases - September 22, 2021 Category: Neurology Authors: Savannah R. Doelfel, Roshini Kalagara, Ethan J. Han, Carlin C. Chuck, Hari Dandapani, Christoph Stretz, Ali Mahta, Linda C. Wendell, Bradford B. Thompson, Shadi Yaghi, Karen L. Furie, Tracy E. Madsen, Michael E. Reznik Tags: Short Communication Source Type: research
Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis
Globally, the number of people estimated to have diabetes mellitus (DM) in 2019 was 463 million, and the estimated number is expected to rise to 578 million people by 2030.1 DM is also associated with an increased risk of atrial fibrillation (AF), 2 and has shown to be an independent risk factor for stroke in patients with AF.3 A meta-analysis of 102 studies further showed that patients with diabetes have a higher risk of all subtypes of stroke (ischemic, hemorrhagic and unclassified stroke).4 This has generated great interest in anti-hyperglycemic agents and their ability to reduce the cardiovascular complications of diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2021 Category: Neurology Authors: How Ting Ong, Yao Hao Teo, Yao Neng Teo, Nicholas LX Syn, Caitlin Fern Wee, Shariel Leong, Alicia Swee Yan Yip, Ray Meng See, Adriel Zhi Hen Ting, Alys ZQ Chia, Alex Jia Yang Cheong, Benjamin Yong-Qiang Tan, Jamie Sin-Ying Ho, Leonard Leong-Litt Yeo, Aloy Source Type: research
