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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hemorrhagic Stroke
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Total 1025 results found since Jan 2013.
Cerebral Microbleeds are an Independent Predictor of Hemorrhagic Transformation Following Intravenous Alteplase Administration in Acute Ischemic Stroke
The objective of our study was to evaluate clinical, laboratory, and imaging predictors on forecasting the risk of hemorrhagic transformation following treatment with rt-PA. We also evaluated the factors associated with cerebral microbleeds that increase the risk of hemorrhagic transformation.
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2018 Category: Neurology Authors: Nandakumar Nagaraja, Nudrat Tasneem, Amir Shaban, Sudeepta Dandapat, Uzair Ahmed, Bruno Policeni, Heena Olalde, Hyungsub Shim, Edgar A. Samaniego, Connie Pieper, Santiago Ortega-Gutierrez, Enrique C. Leira, Harold P. Adams Source Type: research
The Risk of Hemorrhagic Transformation After Thrombolysis for Acute Ischemic Stroke in Chinese Versus North Americans: A Comparative Study
This study aims to compare the incidence of symptomatic hemorrhagic transformation (SHT) among thrombolysis-treated AIS patients in China and in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2018 Category: Neurology Authors: Xiaomeng Xu, Deren Wang, Fang Wang, Casey Norton, Xinfeng Liu, Magdy Selim Source Type: research
Angiographic Blush after Mechanical Thrombectomy is Associated with Hemorrhagic Transformation of Ischemic Stroke
Risk factors for hemorrhagic transformation of ischemic stroke after mechanical thrombectomy (MT) are not well established. We conducted a study to determine if prominent angiographic cerebral vascularity following recanalization with thrombectomy (angiographic blush) is associated with hemorrhagic transformation.
Source: Journal of Stroke and Cerebrovascular Diseases - August 6, 2018 Category: Neurology Authors: Setareh Salehi Omran, Srikanth Reddy Boddu, Aaron M. Gusdon, Benjamin Kummer, Hediyeh Baradaran, Praneil Patel, Iv án Díaz, Babak B. Navi, Ajay Gupta, Hooman Kamel, Athos Patsalides Source Type: research
Antithrombotic Treatment Prior to Intracerebral Hemorrhage: Analysis in the National Acute Stroke Israeli Registry
Intracerebral hemorrhage (ICH) is the most disastrous stroke subtype. Prognosis is considered worse with prior antithrombotic treatment. Our aim was to evaluate the association of prior antithrombotic treatment on the radiological and clinical outcome after ICH in a subgroup of patients included in a national registry.
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2018 Category: Neurology Authors: Roy Romem, David Tanne, Diklah Geva, Michal Einhorn-Cohen, Nir Shlomo, Sara Bar-Yehuda, Sagi Harnof Source Type: research
Analysis of Risk Factors Increased Hemorrhagic Transformation after Acute Ischemic Stroke
The purpose of this study was to analyze the risk factors of hemorrhagic transformation (HT) after intravenous thrombolysis using a recombinant tissue plasminogen activator (r-tPA) in acute ischemic stroke (AIS).
Source: Journal of Stroke and Cerebrovascular Diseases - September 12, 2018 Category: Neurology Authors: Wan-Qian Ge, Jie Chen, Hong Pan, Fei Chen, Cheng-Ye Zhou Source Type: research
Successful mechanical thrombectomy in stroke with thrombolysis-associated intracerebral hemorrhage —a case report
Intravenous thrombolysis and mechanical thrombectomy are the standard of care for patients with acute ischemic stroke with large vessel occlusion. Intracerebral hemorrhage is a main complication of intravenous thrombolysis, however, no data are available on the efficacy and safety of mechanical thrombectomy in patients with thrombolysis-associated intracerebral hemorrhage. This constellation is expected to become more frequent as increasing numbers of patients are treated under the drip-and-ship paradigm.
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2018 Category: Neurology Authors: Johannes M. Weller, Elke Hattingen, Gabor C. Petzold, Felix J Bode Source Type: research
Subacute Elevation of Plasma Level of Caspase-Cleaved Cytokeratin-18 is Associated with Hemorrhagic Transformation and Functional Outcome in Ischemic Stroke
Background: Caspase-cleaved cytokeratin-18 (CCCK-18) is an apoptosis marker. Here, we analyzed the relationship between plasma level of CCCK-18 in the acute and subacute stage of ischemic stroke and early and late functional outcome. Besides, correlation among CCCK-18 and complications, such as hemorrhagic transformation (HT) were also explored. Methods: Plasma concentration of CCCK-18 was investigated in 54 patients at admission and poststroke 72 hours. HT was evaluated by CT scans on 24 poststroke hours.
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2018 Category: Neurology Authors: Tihamer Molnar, Kata Borocz, Timea Berki, Laszlo Szapary, Alex Szolics, Jozsef Janszky, Zsolt Illes, Peter Csecsei Source Type: research
Asymptomatic Intracerebral Hemorrhage May Worsen Clinical Outcomes in Acute Ischemic Stroke Patients Undergoing Thrombectomy
This study aimed to evaluate the clinical effects of AICH and its risk factors in this patient population. Methods: This observational study was based on a prospective registry study. AIS patients with large-vessel occlusion in the anterior circulation and treated with ET were recruited. During thrombectomy procedures, intra-arterial infusion of thrombolytics or antiplatelet and permanent stenting were used as remedial therapies.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2019 Category: Neurology Authors: Fang Jiang, Wenbo Zhao, Chuanjie Wu, Zhen Zhang, Chuanhui Li, Ruiwen Che, Jian Chen, Weiming Hu, Haiqing Song, Jiangang Duan, Xunming Ji Source Type: research
Acute Ischemic Stroke Therapy in Infective Endocarditis: Case Series and Systematic Review
Objectives: To evaluate the safety of acute ischemic stroke (AIS) therapy in patients with infective endocarditis (IE) with intravenous thrombolysis (IVT) or endovascular therapy (EVT) such as mechanical thrombectomy. Methods: We conducted a retrospective study of patients who underwent AIS therapy with IVT or EVT at a tertiary referral center from 2013 to 2017, that were later diagnosed with acute IE as the causative mechanism. We then performed a systematic review of reports of acute ischemic reperfusion therapy in IE since 1995 for their success rates in terms of neurological outcome, and mortality, and their risk of he...
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2019 Category: Neurology Authors: Robert J. Marquardt, Sung-Min Cho, Prateek Thatikunta, Abhishek Deshpande, Dolora Wisco, Ken Uchino Source Type: research
Pathophysiology of Lacunar Stroke: History's Mysteries and Modern Interpretations
Background: Since the term “lacune” was adopted in the 1800s to describe infarctions from cerebral small vessels, their underlying pathophysiological basis remained obscure until the 1960s when Charles Miller Fisher performed several autopsy studies of stroke patients. Methods: He observed that the vessels displayed segme ntal arteriolar disorganization that was associated with vessel enlargement, hemorrhage, and fibrinoid deposition. He coined the term “lipohyalinosis” to describe the microvascular mechanism that engenders small subcortical infarcts in the absence of a compelling embolic source.
Source: Journal of Stroke and Cerebrovascular Diseases - May 27, 2019 Category: Neurology Authors: Robert W. Regenhardt, Alvin S. Das, Ryo Ohtomo, Eng H. Lo, Cenk Ayata, Mahmut Edip Gurol Tags: Review Article Source Type: research
Prognostic Value of Clot Burden Score in Acute Ischemic Stroke after Reperfusion Therapies: A Systematic Review and Meta-Analysis
Background and Aim: Clot burden score (CBS) was designed to weight the thrombus status in cerebral anterior circulation. We performed a systematic review and meta-analysis to investigate the prognostic value of CBS in acute ischemic stroke (AIS) patients undergoing reperfusion therapies. Methods: We searched relevant databases for eligible articles reporting CBS in AIS patients. The effect sizes of good functional outcome, recanalization, or hemorrhagic transformation (HT) were pooled with random-/fixed-effect models.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2019 Category: Neurology Authors: Guoming Li, Guangliang Wu, Zhengjie Qin, Huiping Li, Xiao Cheng, Yefeng Cai Source Type: research
Cardiac Arrhythmias and Acute Cerebrovascular Events: A Case of QT Prolongation and Torsades de Pointes Early After Right Insular Stroke
Stroke involving some areas of the cerebral hemisphere, such as insula, amygdala, and lateral hypothalamus, may cause changes in autonomic control of cardiac function. A 58-year-old woman presented to the emergency department for acute onset of left facial-brachial-crural hemiparesis and dysarthria. A brain CT scan showed subacute ischemic lesion with hemorrhagic infarction in right insular-rolandic cortex. Over the next few days ECG showed severe bradycardia with elongation of QTc, significative pauses (5 seconds), runs of nonsustained ventricular tachycardia and torsades de pointes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2019 Category: Neurology Authors: Ilaria Jane Romano, Antonio Lippolis, Margherita D'Anna, Francesco Gentile Tags: Case Report Source Type: research
Contrast Extravasation is Predictive of Poor Clinical Outcomes in Patients Undergoing Endovascular Therapy for Acute Ischemic Stroke in the Anterior Circulation
To investigate whether contrast extravasation on dual-energy computed tomography (DECT) in patients with acute ischemic stroke (AIS) after endovascular therapy (EVT) are related to hemorrhagic transformation (HT) and poor short-term clinical outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - November 10, 2019 Category: Neurology Authors: Zhongyun Chen, Yingbo Zhang, Yingying Su, Yijia Sun, Yanbo He, Hongbo Chen Source Type: research
Risk analysis of post-procedural intracranial hemorrhage based on STAY ALIVE Acute Stroke Registry
Intracranial hemorrhages (ICH) are classified as symptomatic or asymptomatic according to the presence of clinical deterioration. Here, we aimed to find predictive factors of symptomatic intracranial bleeding in a registry-based stroke research.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2020 Category: Neurology Authors: Peter Csecsei, Gabor Tarkanyi, Edit Bosnyak, Laszlo Szapary, Gabor Lenzser, Alex Szolics, Andras Buki, Peter Hegyi, Alan Abada, Tihamer Molnar Source Type: research
Hemorrhagic stroke and anticoagulation in COVID-19
We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Siddhant Dogra, Rajan Jain, Meng Cao, Seda Bilaloglu, David Zagzag, Sarah Hochman, Ariane Lewis, Kara Melmed, Katherine Hochman, Leora Horwitz, Steven Galetta, Jeffrey Berger Tags: Hemorrhagic stroke in COVID-19 Source Type: research
