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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hemorrhagic Stroke
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Total 1025 results found since Jan 2013.
Acute Hyperglycemia Exacerbates Hemorrhagic Transformation after Embolic Stroke and Reperfusion with tPA: A Possible Role of TXNIP-NLRP3 Inflammasome
Acute hyperglycemia (HG) exacerbates reperfusion injury after stroke. Our recent studies showed that acute HG upregulates thioredoxin-interacting protein (TXNIP) expression, which in turn induces inflammation and neurovascular damage in a suture model of ischemic stroke. The aim of the present study was to investigate the effect of acute HG on TXNIP-associated neurovascular damage, in a more clinically relevant murine model of embolic stroke and intravenous tissue plasminogen activator (IV-tPA) reperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2021 Category: Neurology Authors: Mohd. Salman, Saifudeen Ismael, Li Lexiao, Heba A. Ahmed, Michelle A. Puchowicz, Tauheed Ishrat Source Type: research
Are There Differences in Long-Term Functioning and Recovery Between Hemorrhagic and Ischemic Stroke Patients Receiving Rehabilitation?
Previous research suggested better recovery in functioning of patients with hemorrhagic as compared to ischemic stroke. Now that more effective acute treatment for ischemic stroke, i.e. thrombolysis and thrombectomy, has become available, this observational cohort study aimed to examine if current rehabilitation outcomes differ between patients with hemorrhagic and ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2022 Category: Neurology Authors: Dani ëlla M. Oosterveer, Marieke J.H. Wermer, Gerard Volker, Thea P.M. Vliet Vlieland Source Type: research
Infectious Causes of Stroke
Stroke is one of the primary causes of mortality and morbidity worldwide. It can be ischemic or hemorrhagic, and the former can be due to an in-situ thrombus or a distant embolus. Despite being a rare cause, stroke can also be caused in the setting of infection. Bacterial agents are the most common cause of stroke, among other infectious agents. Until the antibiotic era, rheumatic heart disease was a predisposing risk factor of infective endocarditis. VZV is the most common cause of strokes in pediatric and adult populations.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Sireesha Murala, Elanagan Nagarajan, Pradeep C. Bollu Tags: Review Article Source Type: research
Involvement of T-bet and GATA3 transcription factors in Mesenchymal stem cells and royal jelly combination treatment in brain stroke
Stroke as a common non-communicable disease can manifest itself as ischemic (87%) and hemorrhagic.1 However, the viable cells surrounding the infarct core have been shown to be at risk for infarct and apoptosis. Some therapeutic approaches are trying to improve neuronal recovery in the region and reduce post-stroke disability.2,3 Currently, to dissolve the clot and rescue the surrounding cells in the ischemic condition, tissue plasminogen activator (tPA) is administrated within the first three hours of the onset of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 24, 2022 Category: Neurology Authors: Mohammad Kazemi Arababadi, Mohammad Reza Rahmani, Fatemeh Asadi, Ahmad Shabanizadeh, Aliakbar Yousefi-Ahmadipour Source Type: research
Biomarkers predict hemorrhagic transformation and stroke severity after acute ischemic stroke
Hemorrhagic transformation (HT) is a complication occurring in patients with acute ischemic stroke (AIS) either spontaneously or post-thrombolysis leading to significant morbidity and mortality. We assessed circulating matrix metalloproteinase-9 (MMP-9), Claudin-5, and soluble serum stimulation-2 (sST2) in HT and stroke severity in AIS based on their temporal distribution.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2022 Category: Neurology Authors: Soumya Krishnamoorthy, P.N. Sylaja, Sapna Erat Sreedharan, Gurpreet Singh, Deepa Damayanthi, Srinivas Gopala, UK Madhusoodanan, Harikrishnan Ramachandran Source Type: research
Time to ct scan imaging after symptom onset among ischeamic stroke patients presenting to a quaternary hospital in ghana
This study sought to determine the time of onset of symptoms to the time a CT imaging was done among patients presenting with acute stroke at the Korle-Bu Teaching Hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, B. Agbinko-Djobalar, P. Pekyi-Boateng, M. Amerwornu, P Adjei, A Akpalu, K Nkromah Source Type: research
Dysphagia after ischemic and hemorrhagic stroke: A propensity-matched 20-year analysis of the national inpatient sample
Post-stroke dysphagia (PSD) is a common and debilitating complication of acute stroke associated with increased mortality and morbidity.1,2 Globally, 12.2 million strokes occur every year and 1 in 4 adults over the age of 25 will have a stroke within their lifetime.3 Of these, 87% of strokes are considered ischemic strokes (AIS) and 10% are hemorrhagic (ICH), both of which are associated with dysphagia as an adverse event.4 Recent studies have found that the prevalence of long-term PSD ranges from 42-50% and was an independent risk factor for prolonged hospital stay, institutionalization after discharge, poorer functional ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2023 Category: Neurology Authors: Vikram Vasan, Trevor A. Hardigan, Muhammad Ali, Margaret Downes, Alex Devarajan, Christina P. Rossitto, Braxton R. Schuldt, Ian C. Odland, Christopher P. Kellner, Johanna T. Fifi, J. Mocco, Shahram Majidi Source Type: research
Intravenous Thrombolysis in Thai Patients with Acute Ischemic Stroke: Role of Aging
Conclusions: Thai stroke patients>70 years of age may carry a higher risk of mortality when treated with intravenous rtPA compared to patients ≤70 years of age.
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2011 Category: Neurology Authors: Pornpatr A. Dharmasaroja, Sombat Muengtaweepongsa, Permphan Dharmasaroja Tags: Original Articles Source Type: research
Charlson Comorbidity Index in Ischemic Stroke and Intracerebral Hemorrhage as Predictor of Mortality and Functional Outcome after 6 Months
Conclusions: Comorbid medical conditions independently influence outcome after IS or intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Pedro Enrique Jiménez Caballero, Fidel López Espuela, Juan Carlos Portilla Cuenca, José María Ramírez Moreno, Juan Diego Pedrera Zamorano, Ignacio Casado Naranjo Tags: Original Articles Source Type: research
National Survey of Thrombolytic Therapy for Acute Ischemic Stroke in Taiwan 2003-2010
Data on thrombolytic therapy at the national level is scarce in Asia. Understanding current practice pattern is important for a policy maker in decision making. This cross-sectional study analyzed the utilization pattern of thrombolytic therapy for acute ischemic stroke (AIS) in Taiwan from 2003 through 2010 and identified factors associated with post-therapy intracerebral hemorrhage (ICH) and mortality. From the Taiwan National Health Insurance Research Database, we retrieved inpatient claims for patients with AIS. The frequency of thrombolytic therapy in AIS admissions and its association with the characteristics of pati...
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2013 Category: Neurology Authors: Cheng-Yang Hsieh, Chih-Hung Chen, Yi-Chi Chen, Yea-Huei Kao Yang Tags: Original Articles Source Type: research
Predictors of In-hospital Mortality and the Risk of Symptomatic Intracerebral Hemorrhage after Thrombolytic Therapy with Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke
This study aimed to determine the independent predictors of in-hospital mortality (IHM) and the risk of sICH after rt-PA therapy. A total of 1007 patients (mean age, 72 ± 12 years; 52% women; mean National Institutes of Health Stroke Scale [NIHSS] score, 11.6 ± 5.6) with AIS treated with rt-PA were enrolled in this study during a 42-month period beginning in November 2007. Univariate and multivariate regression analyses were performed to estimate the predictors of IHM. Eighty-three of the 1007 patients (8.2%) died during hospitalization (mean duration of hospitalization, 10 ± 1.8 days). Logistic regression estimated the...
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2012 Category: Neurology Authors: Mohamed Al-Khaled, Christine Matthis, Jürgen Eggers Tags: Original Articles Source Type: research
Nascent Deep Microbleeds and Stroke Recurrences
This study investigated the contributions of nascent deep MBs to stroke recurrence.Methods: We prospectively analyzed nascent deep MBs in patients admitted to our hospital who were treated for index strokes between April 2004 and November 2009. The number of nascent deep MBs was counted on T2∗-weighted MRI scans around 1 year after the index strokes, and compared to previous MRIs on admission. Stroke recurrence–free rate curves were generated using the Kaplan–Meier method using the log-rank test. The odds ratio for nascent deep MBs was derived using a multivariate logistic regression model that was based on recurren...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Ikuhide Kohama, Kazuhisa Yoshifuji, Tatsufumi Nomura, Katsuya Komatsu Tags: Original Articles Source Type: research
Clotting Factors to Treat Thrombolysis-related Symptomatic Intracranial Hemorrhage in Acute Ischemic Stroke
Conclusions: We found no evidence that treatment for sICH with clotting factors has a favorable effect on clinical or radiological outcomes. However, the sample was small because of the low frequency of sICH. New treatments are urgently needed for this uncommon yet serious condition.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2013 Category: Neurology Authors: Yazan J. Alderazi, Niravkumar V. Barot, Hui Peng, Farhaan S. Vahidy, Digvijaya D. Navalkele, Navdeep Sangha, Vivek Misra, Sean I. Savitz Tags: Original Articles Source Type: research
Should Ischemic Stroke Patients with Aphasia or High National Institutes of Health Stroke Scale Score Undergo Preprocedural Intubation and Endovascular Treatment?
Conclusions: Despite the risk of IPI, patients with aphasia or an admission NIHSS score of 20 or more who underwent ET with PPI had lower rates of good outcomes and higher rates of ICH and death.
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2014 Category: Neurology Authors: Ameer E. Hassan, Malik M. Adil, Haralabos Zacharatos, Basit Rahim, Saqib A. Chaudhry, Wondwossen G. Tekle, Adnan I. Qureshi Tags: Original Articles Source Type: research
A Rare Cause of Embolic Stroke in Hereditary Hemorrhagic Telangiectasia
A 57-year-old male patient with hereditary hemorrhagic telangiectasia presented with an acute right middle cerebral artery ischemic stroke. Investigations revealed a right middle cerebral artery M2 occlusion, hypoxemia, and a large pulmonary arteriovenous malformation and right lower limb deep venous thrombosis. Closure of the pulmonary arteriovenous malformation was successfully performed with an Amplatzer device. Catheter closure of pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia is a recognized treatment modality to prevent recurrent ischemic stroke and other embolic and he...
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2013 Category: Neurology Authors: Nawaf Yassi, Bernard Yan, Richard Dowling, Peter J. Mitchell Tags: Case Reports Source Type: research
