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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Hemorrhagic Stroke
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Total 1025 results found since Jan 2013.
Transition in Incidence Rate of Hospitalised Stroke and Case Fatality Rate in the Hunter Region, Australia, 2001-2019: A Prospective Hospital-Based Study
Introduction: Continuous surveillance of stroke admissions has been conducted in the Hunter region, Australia, over the past two decades. We aimed to describe the trends in incidence rates of hospitalised stroke and case-fatality rates in this region, 2001-2019. Methods: From a hospital-based stroke registry, data for admitted adult stroke patients residing in the Hunter region were collected using ICD-10 codes for ischemic and haemorrhagic stroke. Negative binomial regression and logistic regression analysis were used to analyse trends for age-standardised and age-specific incidence rates of hospitalised stroke and 28-day...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2022 Category: Neurology Authors: Yumi Tomari Kashida, Thomas Lillicrap, Rhonda Walker, Elizabeth Holliday, Md Golam Hasnain, Shinya Tomari, Carlos Garcia-Esperon, Jennifer J. Majersik, Neil J. Spratt, Christopher Levi Source Type: research
Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention
Early stroke occurrence after ischemic stroke or transient ischemic attack (TIA) remains a significant risk despite advances in secondary prevention. Ischemic stroke is largely a thromboembolic disease, and major efforts to reduce the early risk of recurrent stroke in patients with non-cardioembolic stroke have focused on antiplatelet strategies.1 Improvements in outcome have been associated with novel antiplatelet strategies, but significant residual risk of ischemic stroke and the potential for major bleeding, including intracranial hemorrhage, limit the effectiveness of these options.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2022 Category: Neurology Authors: Mukul Sharma, Carlos A. Molina, Kazunori Toyoda, Daniel Bereczki, Scott E. Kasner, Helmi L. Lutsep, Georgios Tsivgoulis, George Ntaios, Anna Czlonkowska, Ashfaq Shuaib, Pierre Amarenco, Matthias Endres, Hans Christoph Diener, David Gailani, Anja Kahl, Mar Source Type: research
Long-Term Follow-up of Incidental Intracranial Aneurysms in Patients with Acute Ischemic Stroke
Conclusions: In our study, the prevalence of incidental aneurysm among acute ischemic stroke patients was 6.1%. After 2 years of follow-up, there was no aneurysm rupture or subarachnoid hemorrhage, and the diameter and shape of aneurysms did not change except for 1 patient in whom the aneurysm disappeared.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2011 Category: Neurology Authors: Yoon-Sang Oh, Young-Min Shon, Beum Saeng Kim, A-Hyun Cho Tags: Original Articles Source Type: research
Safety of Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Saccular Intracranial Aneurysms
Conclusions: Intravenous thrombolysis was safe among our patients with acute ischemic stroke and incidental intracranial saccular aneurysm.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2012 Category: Neurology Authors: Manoj K. Mittal, Raymond C.S. Seet, Yi Zhang, Robert D. Brown, Alejandro A. Rabinstein Tags: Original Articles Source Type: research
Antithrombotic Management of Stroke Patients Before Colonoscopy
Conclusions: In this retrospective analysis, there was no significant difference in the occurrence of stroke, myocardial infarction, venous thromboembolism, and major bleeding between patients who had medications continued around the time of colonoscopy versus those who had temporary discontinuation. A prospective, randomized controlled study is warranted to further elucidate this issue.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2012 Category: Neurology Authors: Basel Assaad, Veronica Kemerko Sesi, Renzo Figari, Lonni Schultz, Nithin Thummala, Mohammed Rehman, Arun Chandok, Ann Silverman, Brian Silver Tags: Original Articles Source Type: research
Epidemiology, Pathophysiology, and Treatment of Hypertension in Ischaemic Stroke Patients
Stroke continues to be one of the leading causes of mortality and morbidity worldwide. There are 2 main types of stroke: ischaemic strokes, which are caused by obstruction of the blood vessels leading to or within the brain, and haemorrhagic strokes, which are induced by the disruption of blood vessels. Stroke is a disease of multifactorial aetiology that may develop as an end state in patients with serious vascular conditions—most notably, uncontrolled arterial hypertension—thereby necessitating the effective control of this risk factor to prevent stroke or its recurrence. This paper focuses specifically on the epidem...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Nur Fatirul Hisham, Ulvi Bayraktutan Tags: Review Articles Source Type: research
Short-term Bleeding Events Observed with Clopidogrel Loading in Acute Ischemic Stroke Patients
Discussion: Contrary to our original hypothesis, patients with AIS receiving clopidogrel loading doses within 24 hours of symptom onset did not appear to experience a higher rate of new serious bleeding events during acute hospitalization when compared with patients who did not receive loading doses. The Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke trial is expected to provide insight into the safety of clopidogrel loading as an acute intervention after cerebral ischemia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Lester Y. Leung, Karen C. Albright, Amelia K. Boehme, Joseph Tarsia, Kamal R. Shah, James E. Siegler, Erica M. Jones, Gayle R. Pletsch, Timothy M. Beasley, Sheryl Martin-Schild Tags: Original Articles Source Type: research
Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis-Dependent Patients in the United States
Conclusions: The 2-fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis-dependent patients who present with acute ischemic stroke warrant a careful assessment of risk–benefit ratio in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2013 Category: Neurology Authors: Nauman Tariq, Malik M. Adil, Fahad Saeed, Saqib A. Chaudhry, Adnan I. Qureshi Tags: Original Articles Source Type: research
Pulmonary Embolism in a Stroke Patient after Systemic Thrombolysis: Clinical Decisions and Literature Review
We describe a 73-year-old man who arrived at the emergency room within 2 hours of acute onset of left hemiparesis who was treated with rt-PA and suffered a pulmonary embolism 3 days after acute stroke therapy. rt-PA is also a current therapy for pulmonary embolism, but an ischemic stroke in the previous 3 months is an absolute contraindication to thrombolysis because of the high risk of intracranial hemorrhage. We discuss clinical and therapeutic decisions and review the current literature.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2013 Category: Neurology Authors: Fabio Pilato, Rosalinda Calandrelli, Paolo Profice, Giacomo Della Marca, Aldobrando Broccolini, Giuseppe Bello, Maria Grazia Bocci, Marisa Distefano, Cesare Colosimo, Paolo Maria Rossini Tags: Case Reports Source Type: research
Thrombolysis for Ischemic Stroke in Patients with Brain Tumors
Conclusions: In summary, very limited data exist about thrombolysis in patients with brain tumors. Differentiation of tumor by additional neuroimaging before thrombolysis in ischemic stroke is recommended as thrombolysis might be considered in extra-axial benign appearing neoplasms (eg, meningioma) but is not advisable in intra-axial primary or metastatic neoplasm. Further reporting of thrombolysis in patients with brain tumors is recommended.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2013 Category: Neurology Authors: Thorleif Etgen, Ines Steinich, Lukas Gsottschneider Tags: Original Articles Source Type: research
The iScore Predicts Clinical Response to Tissue Plasminogen Activator in Korean Stroke Patients
Background: Despite substantial differences in clinical features between Asian and Western stroke patients, there are no published prognostic tools validated in an Asiatic population for thrombolytic therapy. We assessed the ability of the iScore to predict the clinical response after intravenous thrombolysis with tissue plasminogen activator (tPA) in a Korean stroke population.Methods: We applied the iScore to eligible participants in the nationwide multicenter stroke registry in Korea. Main outcome measures were poor functional outcome defined as having a modified Rankin Scale score 3-6 and death at 3 months. Symptomati...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Tai Hwan Park, Sang-Soon Park, Youngchai Ko, Soo Joo Lee, Kyung Bok Lee, Jun Lee, Kyusik Kang, Jong-Moo Park, Jay Chol Choi, Dong-Eog Kim, Yong-Jin Cho, Keun-Sik Hong, Joon-Tae Kim, Dae-Hyun Kim, Jae-Kwan Cha, Moon-Ku Han, Ji Sung Lee, Juneyoung Lee, Kyun Tags: Original Articles Source Type: research
A Matched Comparison of Eptifibatide Plus rt-PA Versus rt-PA Alone in Acute Ischemic Stroke
Conclusions: The safety and direction of effect of eptifibatide plus rt-PA were confirmed. A phase III trial is needed to determine the efficacy of eptifibatide plus rt-PA for improving long-term outcomes after AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2014 Category: Neurology Authors: Opeolu Adeoye, William A. Knight, Jane Khoury, Pamela A. Schmit, Heidi Sucharew, Joseph P. Broderick, Arthur M. Pancioli, CLEAR-ER Investigators Tags: Original Articles Source Type: research
A Comparative Study of Dual versus Monoantiplatelet Therapy in Patients with Acute Large-Artery Atherosclerosis Stroke
Background: Antiplatelet drugs are recommended for patients with acute noncardioembolic stroke. However, few randomized clinical trials have investigated the safety and efficacy of dual antiplatelet therapy for these patients. The aim of this study was to evaluate the effects of treatment with clopidogrel and aspirin (combination therapy) and aspirin alone (monotherapy) on neurologic deterioration, platelet activation, and other short-term outcomes in patients with acute large-artery atherosclerosis stroke.Materials and Methods: Altogether 574 patients with acute (≤2 days) large-artery atherosclerosis stroke were random...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2014 Category: Neurology Authors: Xingyang Yi, Jing Lin, Chun Wang, Biao Zhang, Wanzhang Chi Tags: Original Articles Source Type: research
Telemedical Brain Computed Tomography Misinterpretation by Stroke Neurologists Is Not Associated with Thrombolysis-Related Intracranial Hemorrhage
The Stroke Eastern Saxony Network (SOS-NET) provides telecare for acute stroke patients. Stroke neurologists recommend intravenous thrombolysis based on clinical assessment and cerebral computed tomography (CT) evaluation using Alberta Stroke Program Early CT score (ASPECTS). We sought to assess whether ASPECTS misinterpretation by stroke neurologists was associated with thrombolysis-related symptomatic intracranial hemorrhage (sICH).
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2015 Category: Neurology Authors: Charlotte Zerna, Ruediger von Kummer, Johannes Gerber, Kai Engellandt, Andrij Abramyuk, Claudia Wojciechowski, Kristian Barlinn, Jessica Kepplinger, Lars-Peder Pallesen, Timo Siepmann, Imanuel Dzialowski, Heinz Reichmann, Volker Puetz, Ulf Bodechtel Source Type: research
Combined polymorphisms in genes encoding the inflammasome components NLRP3 and CARD8 confer risk of ischemic stroke in men
Stroke is a common medical emergency with high mortality. There are two types of stroke, namely, hemorrhagic stroke and ischemic stroke (IS), and 85 –90% of stroke cases are ischemic. Studies have confirmed that the nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome may be involved in activating the inflammation and pathophysiology of atherosclerosis as well as in mediating inflammatory injury during cerebral ischemia .1
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Jie Lv, Xiaoshan Jiang, Jing Zhang, Xianghui Peng, Hongmei Lin Source Type: research
