Hemorrhagic stroke associated with essential thrombocythemia: Case report and literature review
Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by the overproduction of circulating platelets in the peripheral blood, caused by the excessive proliferation of megakaryocytes in the bone marrow.1 Cerebrovascular events, mainly ischemic stroke, are one of the most serious complications in patients with ET, and the V617F mutation in the Janus kinase 2 (JAK2) gene is recognized as a thrombotic risk factor.2 Hemorrhagic stroke associated with ET is very infrequent, and the effect of mutation types on hemorrhagic stroke remains unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Akihiko Momozaki, Jun Masuoka, Takashi Furukawa, Motofumi Koguchi, Hiroshi Ito, Fumitaka Yoshioka, Kohei Inoue, Atsushi Ogata, Yukiko Nakahara, Tatsuya Abe Tags: Case Report Source Type: research