Filtered By:
Condition: Postnatal Depression
This page shows you your search results in order of relevance.
Order by Relevance | Date
Total 44 results found since Jan 2013.
Gender-Linked Stem Cell Alterations in Stroke and Postpartum Depression.
Abstract
Stroke is a significant unmet clinical need. The current stroke treatment of tissue plasminogen activator is limited to the very acute 4.5 h after disease onset which benefits only less than 3% of ischemic stroke patients. Our overarching hypothesis advances the notion that gender, which has been established as a comorbidity factor of stroke, plays a key role in regenerative medicine, in particular stem cell therapy. We hypothesize that gender is a key factor in culture-induced stemness of adult stem cells. Our goal is to provide new evidence supporting gender effects on stroke and stem cells for the pur...
Source: CNS Neuroscience and Therapeutics - November 15, 2014 Category: Neuroscience Authors: Pabón MM, Ji XM, Fernandez JW, Borlongan CV Tags: CNS Neurosci Ther Source Type: research
Stroke in women: When gender matters
Rev Neurol (Paris). 2021 Jun 22:S0035-3787(21)00563-4. doi: 10.1016/j.neurol.2021.01.012. Online ahead of print.ABSTRACTStroke in women may be considered as a distinct entity due to numerous differences compared with men, including specific epidemiological, etiological, and outcome features along with unique pathophysiological mechanisms. Stroke is the second cause of death in women worldwide with sex-specific causes of stroke in youger women such as pregnancy, post-partum period, oral contraception and migraine. Substitutive hormone treatment in older women is no more recommended in regard of the increased thromboembolic ...
Source: Revue Neurologique - June 26, 2021 Category: Neurology Authors: Q Thomas V Crespy G Duloquin M Ndiaye M Sauvant Y B éjot M Giroud Source Type: research
A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression
Conclusions:
These results indicate that DCEAS could be effective in reducing stroke patients' depressive symptoms. Superficial electrical stimulation in n-CEA group may be beneficial in improving movement disability of stroke patients. A combination of DCEAS and body acupuncture can be considered a treatment option for neuropsychiatric sequelae of stroke.Trial registration: www.clinicaltrials.gov, NCT01174394.
Source: BMC Complementary and Alternative Medicine - July 19, 2014 Category: Complementary Medicine Authors: Sui-Cheung ManBen HungRoger NgXiao-Chun YuHobby CheungMandy FungLeonard LiKwok-Pui LeungKei-Pui LeungKevin TsangEric ZieaVivian WongZhang-Jin Zhang Source Type: research
Want to Prevent Stroke, Diabetes, Cancer? Get Moving … Now!
Worldwide, 81 per cent of school-aged children are not active enough. Photo: WHOBy Baher KamalROME, Feb 2 2017 (IPS)Tired, lazy, bored, laying down long hours watching TV or seated checking your email? Wrong. And dangerous: not enough exercise contributes to cancer, diabetes, depression and other non-communicable diseases. The warning is bold and comes from the United Nations top health organisation, which is urging people to get up and get active.And the risks of inactivity are expanding alarmingly: according to a new document by the World Health Organization (WHO), less and less people are active in many countries – wi...
Source: IPS Inter Press Service - Health - February 2, 2017 Category: Global & Universal Authors: Baher Kamal Tags: Environment Featured Global Headlines Health IPS UN: Inside the Glasshouse TerraViva United Nations Source Type: news
Ceftriaxone pretreatment reduces the propensity of postpartum depression following stroke during pregnancy in rats
Conclusions Taken together, our results suggested that ceftriaxone pretreatment before brain ischemia during pregnancy may reduce the propensity for the development of PPD by preventing the loss of GLT-1 expression in the mPFC.
Source: Neuroscience Letters - August 23, 2016 Category: Neuroscience Source Type: research
Treatment of Depression With Duloxetine in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes
We report a case in which an adult patient with MELAS and comorbid major depressive disorder demonstrated excellent response to the selective serotonin-norepinephrine reuptake inhibitor medication duloxetine.
Source: Clinical Neuropharmacology - May 1, 2018 Category: Neurology Tags: Case Reports Source Type: research
Role of TREK-1 in Health and Disease, Focus on the Central Nervous System
Conclusion and Perspectives
Since their cloning 20 years ago, the physiological importance of TREK-1 channels has continued to grow (Figure 3). Today, TREK-1 channels have been shown to be important and their presence is essential in a number of physiopathological processes. Their involvement in these different processes demonstrate the necessity to design pharmacological modulators, activators or inhibitors, of these channels to correct any TREK-1-related dysfunctions.
Despites a number of studies and many molecule screenings, only few putative new drugs were identified. The activators belonging to the ML and BL series ...
Source: Frontiers in Pharmacology - April 10, 2019 Category: Drugs & Pharmacology Source Type: research
Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1
1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom
2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom
Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research
Yoga Saved My Life: My Journey From Worrier To Warrior
A year ago today I went blind. Nine days after the birth of my daughter, my brain began to bleed and I awoke in the Intensive Care Unit-I had suffered a stroke. My left side function had been compromised, my vision was blurred, and the hope of being home for my brand new baby was shattered. Before the bleed I was a healthy and happy 34-year-old woman, after the bleed I became someone I could not even recognize.
After two weeks my vision slowly returned, the swelling in my brain had not disappeared; but diminished, and I was released to go home and attempt to resume a new kind of normal as a Stroke Survivor. I was sent ho...
Source: Healthy Living - The Huffington Post - July 5, 2016 Category: Consumer Health News Source Type: news
An Unusual Cause of Hyperglycemia
BY CHRISTINE SHEELER; SEEMA ELAHI, MDA 46-year-old man presented to the ED with multiple complaints, including fatigue and dizziness for one day. His primary care physician had diagnosed him with diabetes the previous day, and had prescribed him an oral hypoglycemic as well as insulin. Neither, however, was started at the time of presentation. The patient had a medical history significant for HIV, with his most recent CD4 count above 500, and bilateral sensorineural hearing loss, which had progressively worsened since its initial onset in his 20s. His physical exam was unremarkable except for decreased hearing bilateral...
Source: The Case Files - April 13, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain
This study was carried out in accordance with the recommendations of National Animal Welfare Authority, Ireland. The protocol was approved by the Animal Ethical Committee Trinity College Dublin and HPRA.Author ContributionsAS performed the experiments and wrote the paper; KH provided assistance in the design and analysis of the RNAseq experiment; DT contributed to sample extraction and establishment of the colony; and DT and MG designed and supervised all the parts of the research and the writing of the manuscript.FundingThe study was funded by the Wellcome Trust Grant WT079408/C/06/Z issued to MG, and by an SFI FN Funded ...
Source: Frontiers in Psychiatry - April 29, 2019 Category: Psychiatry Source Type: research
Investigating the causal association of postpartum depression with cerebrovascular diseases and cognitive impairment: a Mendelian randomization study
ConclusionThe causal association between PPD and cognitive impairment indicates that cognitive impairment is a critical aspect of PPD and thus cannot be regarded as an epiphenomenon. Addressing cognitive impairment and lessening the symptoms associated with PPD independently play significant roles in the treatment of PPD.
Source: Frontiers in Psychiatry - June 22, 2023 Category: Psychiatry Source Type: research
Peripartum antidepressant use is associated with an increased risk of postpartum haemorrhage
Commentary on: Palmsten K, Hernández-Díaz S, Huybrechts KF, et al.. Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States. BMJ 2013;347:f4877. Context Increased incidence of postpartum haemorrhage (PPH) is reported in a number of high-resource settings since the 1990s. The increase appears unrelated to factors such as rising rates of caesarean sections or increasing maternal age.1 Recent studies have investigated the association between antidepressant use at different stages of pregnancy and PPH, with two studies demonstrating a 1.20-fol...
Source: Evidence-Based Medicine - March 19, 2014 Category: Internal Medicine Authors: Ford, J. B., Morris, J. M. Tags: EBM Aetiology, Health policy, Epidemiologic studies, Drugs: CNS (not psychiatric), Stroke, Pregnancy, Anxiety disorders (including OCD and PTSD), Child and adolescent psychiatry, Mood disorders (including depression), Drugs: musculoskeletal and joint dise Source Type: research
