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What Prohibition Can Teach Us About Drug and Alcohol Policy Today
It’s widely understood today that drinking while pregnant is harmful for the fetus. But the link between alcohol and the health of infants wasn’t as well known in the 1930s, when prohibition was repealed in the U.S. and all sorts of people, pregnant women included, began drinking again.Because prohibition was lifted on a piecemeal basis across the U.S., some counties continued to prohibit alcohol, or stay “dry,” while their neighboring counties were “wet.” Those conditions created what economists call a natural experiment, and made it possible to track the health impacts of maternal drin...
Source: TIME: Health - August 2, 2023 Category: Consumer Health News Authors: Oliver Staley Tags: Uncategorized Public Health Source Type: news

The effects of a dialogue-based intervention to promote psychosocial well-being after stroke: a randomized controlled trial.
CONCLUSION: The results of this trial did not demonstrate lower levels of emotional distress and anxiety or higher levels of health-related quality of life in the intervention group (dialogue-based intervention) as compared to the control group (usual care) at 12 months post-stroke. PMID: 32517513 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - June 9, 2020 Category: Rehabilitation Authors: Bragstad LK, Hjelle EG, Zucknick M, Sveen U, Thommessen B, Bronken BA, Martinsen R, Kitzmüller G, Mangset M, Kvigne KJ, Hilari K, Lightbody CE, Kirkevold M Tags: Clin Rehabil Source Type: research

This Under-Utilized Drug Is Actually Critical for Treatment-Resistant Depression
Many people with clinical depression have tried an array of medication and still feel sick. Maybe they’ve tried different selective serotonin reuptake inhibitors (SSRIs) or selective norepinephrine reuptake inhibitors (SNRIs). Maybe they’ve taken these antidepressants along with an antipsychotic (a common strategy to boost effectiveness). Either way, the lack of improvement can make individuals feel even more hopeless and fear the darkness will never lift. If this sounds all-too familiar, you’re definitely not alone. In fact, up to 30 percent of people with depression don’t respond to the first few antidepressants ...
Source: Psych Central - November 27, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Antidepressants Depression Disorders ECT General Medications Treatment Atypical Depression difficult to treat depression Managing Depression MAOIs medication for depression Monoamine Oxidase Inhibitors Severe Depression Treatin Source Type: news

Effect of a dialogue-based intervention on psychosocial well-being 6 months after stroke in Norway: A randomized controlled trial.
CONCLUSION: Psychosocial well-being improved during the first 6 months after stroke in both arms of the trial, but no statistically significant benefit of the dialogue-based intervention was found compared with usual care. PMID: 31411337 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - August 15, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

CNS Summit 2016 Abstracts of Poster Presentations
Conclusion: Subjects with acutely exacerbated schizophrenia who were eligible for discharge from the inpatient setting and who completed the study demonstrated high rates of adherence using the mobile AI application. Subjects were able to easily use the technology. Use of the platform did not appear to increase the dropout rate. This study demonstrates the feasibility of using AI platforms to ensure high adherence, provide reliable adherence data, and rapidly detect nonadherence in CNS trials. Disclosures/funding: Adam Hanina and Laura Shafner are employees of AiCure, New York, New York, and consultants to Takeda. Xinxin D...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Devices Drug Development Evaluations Genetics Medical Issues Neurology Patient Assessment Proceedings Psychiatry Psychopharmacology Scales Supplements Technology Trial M Source Type: research

Food addiction: Definition, measurement and limits of the concept, associated factors, therapeutic and clinical implications.
Abstract Addictions, which are characterized by the inability to control a behavior despite existence of physical or psychological consequences, have biological, psychological and social determinants. Although the possibility of developing an addiction to some psychoactive substances (e.g. alcohol, tobacco, cannabis) and to gambling (i.e., gambling disorder) is now well demonstrated, the possibility to develop a non-drug addiction (i.e., behavioral addiction) to certain behaviors which provide pleasure (e.g. eating, having sex, buying things) is still in debate. The concept of food addiction, which refers to peopl...
Source: Presse Medicale - May 18, 2016 Category: Journals (General) Authors: Cathelain S, Brunault P, Ballon N, Réveillère C, Courtois R Tags: Presse Med Source Type: research

Rethinking Retirement in the 21st Century
Conclusion In the 21st century, many seniors are not retiring from something. Instead, retirement is an opportunity for reinventing, reimagining and reconnecting to one's self, family, friends and community. Robert Browning once wrote, "Grow old along with me! The best is yet to be." By investing in your physical, mental and financial health today, you can help ensure that your best years are just ahead. Rear Admiral Susan Blumenthal, M.D., M.P.A. (ret.) is the Public Health Editor of The Huffington Post. She is a Senior Fellow in Health Policy at New America and a Clinical Professor at Tufts and Georgetown University Sc...
Source: Healthy Living - The Huffington Post - May 1, 2015 Category: Consumer Health News Source Type: news

Late onset bipolar disorder due to a lacunar state.
CONCLUSION: Our case sheds light on the role of the basal ganglia in mood disorders and the importance of ruling out brain injury in late onset BD. PMID: 23963241 [PubMed - as supplied by publisher]
Source: Behavioural Neurology - August 20, 2013 Category: Neurology Authors: Antelmi E, Fabbri M, Cretella L, Guarino M, Stracciari A Tags: Behav Neurol Source Type: research