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Total 381 results found since Jan 2013.

Repeatability of quantitative T1rho magnetic resonance imaging in normal brain tissues at 3.0T
T1rho imaging is a quantitative MRI technique based on the properties of spin –lattice relaxation in the rotating frame, otherwise known as T1rho relaxation. The measured signal is obtained by the decay of magnetisation in the transverse plane, in the presence of a spin-lock radiofrequency field. T1rho is sensitive to low frequency interactions, and provides a viable approa ch to assess the macromolecular environment inside tissues. In recent years, quantitative T1rho imaging has been increasingly explored in various neurological conditions such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s Di...
Source: Physica Medica: European Journal of Medical Physics - July 21, 2023 Category: General Medicine Authors: Lei Wang, Weitian Chen, Yurui Qian, Tiffany Y. So Source Type: research

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

Brain health and mental health: Common vascular risk factors and practical implications
Alzheimers Dement. 2023 May 22. doi: 10.1002/alz.13153. Online ahead of print.ABSTRACTThe pandemic dramatized the close links among cognitive, mental, and social health; a change in one reflects others. This realization offers the opportunity to bridge the artificial separation of brain and mental health, as brain disorders have behavioral consequences and behavioral disorders affect the brain. The leading causes of mortality and disability, namely stroke, heart disease, and dementia, share the same risk and protective factors. It is emerging that bipolar disorders, obsessive compulsive disorders, and some depressions shar...
Source: The Journal of Alzheimers Association - May 22, 2023 Category: Psychiatry Authors: Vladimir Hachinski Ennapadam Krishnamoorthy Levent Kuey Laurence J Kirmayer Source Type: research

Directional recordings of somatosensory evoked potentials from the sensory thalamus in chronic poststroke pain patients
CONCLUSIONS: SEP recordings from directional DBS leads offer additional information about the neurophysiological (re)organization of the sensory thalamus.SIGNIFICANCE: Directional recordings of thalamic SEPs bear the potential to assist clinical decision-making in DBS for pain.PMID:37156120 | DOI:10.1016/j.clinph.2023.03.359
Source: Clinical Neurophysiology - May 8, 2023 Category: Neurology Authors: Andreas Nowacki David Zhang Jonathan Wermelinger Pablo Abel Alvarez Abut Jan Rosner Claudio Pollo Kathleen Seidel Source Type: research

Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
CONCLUSION: Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.PMID:36819979 | PMC:PMC9938786 | DOI:10.1155/2023/7989712
Source: Case Reports in Psychiatry - February 23, 2023 Category: Psychiatry Authors: Heidi Madeleine Latvala Solveig Kl æbo Reitan Arne Einar Vaaler Source Type: research

Is there a bidirectional relationship between stroke risk and mood disorders in older adult patients?
Research suggests that there may be a causal relationship between stroke and depression symptoms. However, the direction of this relationship remains unclear, which suggests the possibility that it is bidirectional.   Indeed, some findings suggest that depression is a common occurrence post-stroke and that individuals who have a greater stroke risk are also more likely to have depression. Conversely, there is also evidence that depression may be a risk factor for stroke. In addition, although most of the liter ature focuses on the relationship between cardiovascular health and depression, less is known about other mood di...
Source: The American Journal of Geriatric Psychiatry - February 17, 2023 Category: Geriatrics Authors: Ana Trueba, Boyu Ren, Regan E. Patrick, David G. Harper, Brent P. Forester Tags: Poster Number: NR-10 Source Type: research

Screening for obstructive sleep apnoea in high-risk patients with mood disorders
CONCLUSIONS: This pilot study showed an increased risk of OSA in patients with mood disorders. Psychiatric patients with identified risk factors should be routinely screened for obstructive sleep apnoea and referred to proper treatment.PMID:36528884
Source: Neuroendocrinology Letters - December 18, 2022 Category: Endocrinology Source Type: research