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Condition: Diabetes Mellitus
Nutrition: Calcium

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Total 122 results found since Jan 2013.

Low intakes of carotene, vitamin  B2, pantothenate and calcium predict cognitive decline among elderly patients with diabetes mellitus: The Japanese Elderly Diabetes Intervention Trial
ConclusionsThese findings suggest that sufficient intakes of carotene, vitamin B2, pantothenate, calcium and vegetables could help prevent cognitive decline among elderly men with diabetes mellitus. Geriatr Gerontol Int 2016; ••: ••–••.
Source: Geriatrics and Gerontology International - July 17, 2016 Category: Geriatrics Authors: Atsushi Araki, Yukio Yoshimura, Takashi Sakurai, Hiroyuki Umegaki, Chiemi Kamada, Satoshi Iimuro, Yasuo Ohashi, Hideki Ito, Tags: Original Article: Epidemiology, Clinical Practice and Health Source Type: research

Design and baseline characteristics of the LANDMARK study
Conclusions The LANDMARK study will determine whether LC, a non-Ca-based P binder, reduces cardiovascular mortality and morbidity in chronic hemodialysis patients.
Source: Clinical and Experimental Nephrology - July 11, 2016 Category: Urology & Nephrology Source Type: research

Circulating Proneurotensin Concentrations and Cardiovascular Disease Events in the Community: The Framingham Heart Study.
CONCLUSIONS: Higher concentrations of proneurotensin are associated with a greater risk of incident cardiovascular events in the community. This association did not vary according to sex, baseline low-density lipoprotein, or sortilin receptor 1 genotype. PMID: 27312221 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 15, 2016 Category: Cardiology Authors: Januzzi JL, Lyass A, Liu Y, Gaggin H, Trebnick A, Maisel AS, D'Agostino RB, Wang TJ, Massaro J, Vasan RS Tags: Arterioscler Thromb Vasc Biol Source Type: research

Coronary artery calcium scores and cardiovascular risk factors in 31,545 asymptomatic Korean adults
Abstract The aims of this study were to identify the distribution of coronary artery calcium score (CACS) by age group and cardiovascular (CV) risk factors and to evaluate the association between CV risk factors and CACS classification in asymptomatic adults. The study included 31,545 asymptomatic Koreans, over 20 years of age with no previous history of malignancy, proven coronary artery disease, or stroke, who underwent CACS computed tomography at the Health Promotion Center, Samsung Medical Center, between January 2005 and June 2013. Mean (±SD) age was 53.8 (±8.5) years overall, 56.1 (±8.3) in men, and 53.3 ...
Source: The International Journal of Cardiovascular Imaging - April 26, 2016 Category: Radiology Source Type: research

Middle Cerebral Artery Calcification: Association With Ischemic Stroke
This study retrospectively included 354 subjects with ischemic stroke in the MCA territory and 1518 control subjects who underwent computed tomography (CT) of the brain. We recorded major known risk factors for ischemic stroke, including age, gender, hypertension, diabetes mellitus, smoking, hyperlipidemia, and obesity, along with the MCA calcium burden, measured with the Agatston calcium scoring method. Univariate and modified logistic regression analyses were performed to examine the association between the MCA calcification and ischemic stroke. The univariate analyses showed significant associations of ischemic stroke w...
Source: Medicine - December 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A Systematic Review on the Efficacy of Amlodipine in the Treatment of Patients With Hypertension With Concomitant Diabetes Mellitus and/or Renal Dysfunction, When Compared With Other Classes of Antihypertensive Medication
The long-term cardiovascular (CV) effects of calcium channel blockers, with special focus on amlodipine, were compared with other classes of antihypertensive medications in high-risk hypertensive patient subgroups. A systematic literature review and meta-analysis was undertaken of 38 unique randomized, active-controlled, parallel-group trials comparing amlodipine/calcium channel blockers with diuretics, β-blockers, α-blockers, angiotensin-converting enzyme inhibitors, or angiotensin II receptor blockers, with ≥6-month follow-up, and which had included assessment of blood pressure (BP) and CV events [all-cause death, CV...
Source: American Journal of Therapeutics - September 1, 2015 Category: Drugs & Pharmacology Tags: Original Articles Source Type: research

HYT-Hypertension in Turkey: A Cross-Sectional Survey on Blood Pressure Control with Calcium Channel Blockers Alone or Combined with Other Antihypertensive Drugs
Conclusions Taken together these findings provide evidence that dihydropyridine-type CCBs, particularly when combined with ACE-inhibitors or angiotensin II receptors blockers, allow to achieve a blood pressure control better than the one reported in the same geographic area by other treatment strategies based on different combinations of diuretics, beta-blockers, ACE-inhibitors, angiotensin II receptors blockers and calcium channel blockers.
Source: High Blood Pressure and Cardiovascular Prevention - April 22, 2015 Category: Cardiology Source Type: research

Elevated Parathyroid Hormone, But Not Vitamin D Deficiency, Is Associated With Increased Risk of Heart Failure in Older Men With and Without Cardiovascular Disease Original Articles
Conclusions— Elevated PTH, but not 25-hydroxyvitamin D or other markers of mineral metabolism, is associated with increased risk of HF in both older men with and without myocardial infarction/stroke. This increased risk was not explained by its association with known risk factors for HF. Further studies are now needed to elucidate the mechanisms underlying this association.
Source: Circulation: Heart Failure - September 16, 2014 Category: Cardiology Authors: Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. H., Sattar, N. Tags: Congestive, Epidemiology Original Articles Source Type: research

Antihypertensive treatment and risk of atrial fibrillation: a nationwide study
Conclusion Use of ACEis and ARBs compared with β-blockers and diuretics associates with a reduced risk of atrial fibrillation, but not stroke, within the limitations of a retrospective study reporting associations. This suggests that controlling activation of the renin-angiotensin system in addition to controlling blood pressure is associated with a reduced risk of atrial fibrillation.
Source: European Heart Journal - May 7, 2014 Category: Cardiology Authors: Marott, S. C. W., Nielsen, S. F., Benn, M., Nordestgaard, B. G. Tags: Hypertension Source Type: research

Coffee and tea: perks for health and longevity?
Abstract PURPOSE OF REVIEW: Tea and coffee, after water, are the most commonly consumed beverages in the world and are the top sources of caffeine and antioxidant polyphenols in the American diet. The purpose of this review is to assess the health effects of chronic tea and/or coffee consumption. RECENT FINDINGS: Tea consumption, especially green tea, is associated with significantly reduced risks for stroke, diabetes and depression, and improved levels of glucose, cholesterol, abdominal obesity and blood pressure. Habitual coffee consumption in large epidemiological studies is associated with reduced mortali...
Source: Diabetes Metab - September 25, 2013 Category: Endocrinology Authors: Bhatti SK, O'Keefe JH, Lavie CJ Tags: Curr Opin Clin Nutr Metab Care Source Type: research

Analysis of the structure of calpain-10 and its interaction with the protease inhibitor SNJ-1715
Abstract: Calpain-10 (CAPN10) is a cysteine protease that is activated by intracellular calcium (Ca2+) and known to be involved in diseases such as cancer, heart attack, and stroke. A role for the CAPN10 gene in diabetes mellitus type II was recently identified. Hyper activation of the enzyme initiates a series of destructive cycles that can cause irreversible damage to cells. The development of inhibitors may be useful as therapeutic agents for a number of calpainopathies. In this paper, we have used the homology modelling technique to determine the 3D structure of calpain-10 from Homo sapiens. The model of calpain-10 obt...
Source: Computers in Biology and Medicine - September 19, 2013 Category: Bioinformatics Authors: Ronaldo Correia da Silva, Nelson Alberto N. de Alencar, Cláudio Nahum Alves, Jerônimo Lameira Source Type: research

Ischemic Stroke: Measurement of Intracranial Artery Calcifications Can Improve Prediction of Asymptomatic Coronary Artery Disease Neuroradiology
Conclusion: The IAC scores quantified by using unenhanced CT correlate significantly with coronary calcium scores and may serve as an independent predictor of asymptomatic CAD in patients with ischemic stroke. © RSNA, 2013
Source: Radiology - August 22, 2013 Category: Radiology Authors: Ahn, S. S., Nam, H. S., Heo, J. H., Kim, Y. D., Lee, S.-K., Han, K. H., Choi, B. W., Kim, E. Y. Tags: Neuroradiology, Vascular Imaging Source Type: research

Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress
Conclusions: These results suggest that AGEs enhance vascular calcification partly through a RAGE/oxidative stress pathway.
Source: BMC Cardiovascular Disorders - March 5, 2013 Category: Cardiology Authors: Qin WeiXiaomei RenYibo JiangHong JinNaifeng LiuJie Li Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function.  >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news