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Total 125 results found since Jan 2013.

Atypical chest pain in ACS: a trap especially for women.
Abstract Not all acute coronary syndromes (ACS) exhibit the classic symptoms of chest pain. The diagnosis of ACS in patients without typical chest pain is often challenging. These patients are at increased risk for delayed or incorrect diagnosis, less aggressive treatment and high in-hospital mortality. The association between diabetes mellitus and absence of chest pain in ischemic heart disease is established. As well, it is known that women, more frequently than men, have atypical presentation. However, there is a lack of standardization in characterizing the population of patients with ACS and atypical presenta...
Source: Current Pharmaceutical Design - March 8, 2016 Category: Drugs & Pharmacology Authors: Ricci B, Cenko E, Varotti E, Puddu PE, Manfrini O Tags: Curr Pharm Des Source Type: research

Abstract 251: The Association Between Receipt of Healthcare Services and Post-stroke Hypertension Control Session Title: Abstract Poster Session II
We examined the receipt of health care services by patients in the one-year period following discharge for ischemic stroke.This was a retrospective cohort study of patients who were admitted for acute ischemic stroke at a Veterans Affairs hospital during year 2011 and who were discharged with a BP >140/90 mmHg. The following were reviewed: primary care visits; sub-specialty clinic visits; emergency department (ED) visits; hospitalizations; utilization of ancillary care (i.e., telehealth, pharmacy, nutrition services); medications upon discharge; adherence to medications and occurrence of recurrent stroke during the one-...
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: Kohok, D., Sico, J. J., Baye, F., Myers, L., Masoor, K., Bravata, D. M. Tags: Session Title: Abstract Poster Session II Source Type: research

Outcomes for Patients With Diabetes After Continuous-Flow Left Ventricular Assist Device Implantation
Diabetes mellitus (DM) affects an estimated 366 million people worldwide, and confers a markedly increased risk of cardiovascular disease, including coronary artery disease (CAD), stroke, and HF.1 Diabetes is an independent mortality risk factor for HF patients at follow-up intervals of 1 –8 years.2–5 Decompensated HF is an insulin-resistant state, promoting hyperglycemia in patients with and without DM. Independently from DM status, blood glucose level at HF hospital admission is prognostic for 30-day mortality.
Source: Journal of Cardiac Failure - February 24, 2016 Category: Cardiology Authors: Amanda R. Vest, Stanley M. Mistak, Rory Hachamovitch, Maria M. Mountis, Nader Moazami, James B. Young Tags: Clinical Investigation Source Type: research

Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry
In this study, we aimed to identify which factors were associated with adverse outcomes of a minor stroke. Methods: The China National Stroke Registry (CNSR) is a nationwide prospective registry for patients presented to hospitals with acute cerebrovascular events between September 2007 and August 2008. The 3-month follow-up was completed in 4669 patients with a minor stroke defined as the initial neurological severity lower than 4 in the National Institutes of Health Stroke Scale (NIHSS). Multivariate model was used to determine the association between risk factors and clinical outcomes. Results: Of 4669 patients with a m...
Source: BMC Neurology - December 9, 2015 Category: Neurology Authors: Lingyun WuAnxin WangXianwei WangXingquan ZhaoChunxue WangLiping LiuHuaguang ZhengYongjun WangYibin CaoYilong Wangon behalf of the China National Stroke Registry investigators Source Type: research

Prior chronic clopidogrel therapy is associated with increased adverse events and early stent thrombosis.
Abstract Despite the growing use of clopidogrel, limited data exist regarding the prognostic significance of chronic clopidogrel therapy in patients sustaining acute coronary syndrome (ACS). Our aim was to determine whether patients sustaining ACS while on chronic clopidogrel therapy have a worse prognosis than clopidogrel-naïve patients. A total of 5,386 consecutive ACS patients were prospectively characterised and followed-up for 30 days. Of them, 680 (13 %) were treated with clopidogrel prior to the index ACS. Major adverse cardiovascular events (MACE) were defined as death, recurrent ACS, stroke and/or sten...
Source: Thrombosis and Haemostasis - October 8, 2015 Category: Hematology Authors: Asher E, Fefer P, Sabbag A, Herscovici R, Regev E, Mazin I, Shlomo N, Zahger D, Atar S, Hammerman H, Polak A, Beigel R, Matetzky S, PLATIS (Platelets and Thrombosis in Sheba) Study Group Tags: Thromb Haemost Source Type: research

Ethnic Differences in Associations Between Blood Pressure and Stroke in South Asian and European Men Epidemiology/Population
We report findings from a UK cohort study of 1375 European and 1074 South Asian men, not receiving antihypertensive medication, aged 40 to 69 years at baseline (1988–1991). Assessment included BP, blood tests, anthropometry, and questionnaires. Incident stroke was established at 20 years from death certification, hospital and primary care records, and participant report. South Asians had higher systolic BP, diastolic BP, and mean arterial pressure than Europeans, and similar pulse pressure. Associations between systolic BP or diastolic BP and stroke were stronger in South Asians than Europeans, after adjustment for a...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Eastwood, S. V., Tillin, T., Chaturvedi, N., Hughes, A. D. Tags: Cerebrovascular disease/stroke, Risk Factors, Epidemiology Epidemiology/Population Source Type: research

The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Introduction Blue light information plays an important role in synchronising internal biological rhythm within the external environment. Circadian misalignment is associated with the increased risk of sleep disturbance, obesity, diabetes mellitus, depression, ischaemic heart disease, stroke and cancer. Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). At present, clear intraocular lenses (IOLs) and blue-blocking IOLs are both widely used for cataract surgery; there is currently a lack of randomised controlled trials to determine whether clear...
Source: BMJ Open - May 12, 2015 Category: Journals (General) Authors: Nishi, T., Saeki, K., Obayashi, K., Miyata, K., Tone, N., Tsujinaka, H., Yamashita, M., Masuda, N., Mizusawa, Y., Okamoto, M., Hasegawa, T., Maruoka, S., Ueda, T., Kojima, M., Matsuura, T., Kurumatani, N., Ogata, N. Tags: Open access, Epidemiology, Ophthalmology Protocol Source Type: research

Weather as physiologically equivalent was not associated with ischemic stroke onsets in Vienna, 2004-2010.
Abstract Stroke rates were found to have seasonal variations. However, previous studies using air temperature, humidity, or air pressure separately were not adequate, and the study catchment was not clearly drawn. Therefore, here we proposed to use a thermal index called physiologically equivalent temperature (PET) that incorporates air temperature, humidity, wind speed, cloud cover, air pressure and radiation flux from a biometeorological approach to estimate the effect of weather as physiologically equivalent on ischemic stroke onsets in an Austrian population. Eight thousand four hundred eleven stroke events in...
Source: Environmental Science and Pollution Research International - April 16, 2015 Category: Environmental Health Authors: Ferrari J, Shiue I, Seyfang L, Matzarakis A, Lang W, Austrian Stroke Registry Collaborators Tags: Environ Sci Pollut Res Int Source Type: research

Management and 1-Year Outcomes of Patients With Atrial Fibrillation in the Middle East: Gulf Survey of Atrial Fibrillation Events
We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as hypertension (59%), diabetes (33%), and coronary artery disease (33%). Warfarin was not prescribed to 40% of patients with Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke/TIA2 score of ≥2. One-year rates of stroke/transient ischemic attack (TIA) and all-cause morta...
Source: Angiology - April 15, 2015 Category: Cardiology Authors: Zubaid, M., Rashed, W. A., Alsheikh-Ali, A. A., Al-Zakwani, I., AlMahmeed, W., Shehab, A., Sulaiman, K., Qudaimi, A. A., Asaad, N., Amin, H., on behalf of the Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) Investigators Tags: Atrial Fibrillation Source Type: research

Isolated Unilateral Ptosis due to Paramedian Midbrain Infarction
A 59-year-old man who had hypertension, dyslipidemia, diabetes mellitus, and left eye glaucoma developed sudden vertigo and left ptosis; he did not notice diplopia. He visited our hospital on day 3 after onset and neurologic examination showed left ptosis. His left visual acuity was counting fingers, and the light reflex was sluggish owing to glaucoma. Pupil sizes were equal, and eye movements and the lower lid were unremarkable. Magnetic resonance images revealed an acute infarction of the left paramedian midbrain.
Source: Journal of Stroke and Cerebrovascular Diseases - March 25, 2015 Category: Neurology Authors: Eriko Sugawara, Haruko Nakamura, Masanao Endo, Fumiaki Tanaka, Tatsuya Takahashi Tags: Case Report Source Type: research

Many African Americans Still Only Dream of High Quality Health Care
Recently, AARP conducted a study to determine how perceptions of key social issues ranked in importance to African Americans age 50 and over. Ninety-one percent gave the answer "high quality health care." Eighty-nine percent gave the answer, "Access to high quality health care information." We were not surprised at the high percentage of either response. Why wouldn't the foremost issue on the minds of African Americans be the key issue that would prolong, enhance or save lives? Why wouldn't the dominant issue on the minds of Black people age 50 and over be their health; even more so than education, employment and access t...
Source: Healthy Living - The Huffington Post - February 16, 2015 Category: Consumer Health News Source Type: news

Otitis Media Leads to Brain Abscess Presenting as Stroke
By Mikhail Elfond, DO; Esi Quayson, MD; & Joseph V.M. Kelly, MD, MBA   A 65-year-old man presented to the ED via EMS with symptoms of stroke. The paramedics stated his right-sided weakness and speech difficulty started 40 minutes prior to presentation in the ED. En route to the hospital, paramedics observed four episodes of facial twitching.     Vitals signs were significant for a rectal temperature of 100.2°F and a fingerstick blood sugar of 220 mg/dL. History of present illness was significant for a diagnosis of left otitis media treated with Augmentin and Vicodin at an urgent care center one day prior to prese...
Source: The Case Files - January 20, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: research

The global impact of non-communicable diseases on healthcare spending and national income: a systematic review
Abstract The impact of non-communicable diseases (NCDs) in populations extends beyond ill-health and mortality with large financial consequences. To systematically review and meta-analyze studies evaluating the impact of NCDs (including coronary heart disease, stroke, type 2 diabetes mellitus, cancer (lung, colon, cervical and breast), chronic obstructive pulmonary disease and chronic kidney disease) at the macro-economic level: healthcare spending and national income. Medical databases (Medline, Embase and Google Scholar) up to November 6th 2014. For further identification of suitable studies, we searched refere...
Source: European Journal of Epidemiology - January 18, 2015 Category: Epidemiology Source Type: research

Low HDL cholesterol is correlated to the acute ischemic stroke with diabetes mellitus
Background: To clarify the role of lipid composition in the occurrence of acute ischemic stroke (AIS) with diabetes mellitus (DM) and its influence factors. Methods: Data was collected from the patients hospitalization in Affiliated Drum Tower Hospital of Nanjing University Medical School from October 2008 to May 2012, which included AIS and non-AIS consist of transient ischemic attack (TIA) and Vertigo or dizzy. Lipid and other risk factors including blood glucose (BG), uric acid (UA), hypertension, DM and atrial fibrillation (AF) were investigated in relation to occurrence of AIS. Results: The level of high density lipop...
Source: Epidemiologic Perspectives and Innovations - November 14, 2014 Category: Epidemiology Authors: Yun LuoJingwei LiJunfeng ZhangYun Xu Source Type: research