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Condition: Hughes Syndrome

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Total 523 results found since Jan 2013.

Antiphospholipid Syndrome
Antiphospholipid syndrome information page compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research

Altered Fibrin Clot Properties in Patients With Cerebral Venous Sinus Thrombosis: Association With the Risk of Recurrence Brief Reports
Conclusions— CVST is associated with the formation of more compact plasma fibrin clots and resistance to fibrinolysis, which may predispose to the recurrence.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Siudut, J., Świat, M., Undas, A. Tags: Fibrinolysis, Fibrinogen/fibrin, Cerebral Venous Thrombosis Brief Reports Source Type: research

Pregnancy loss and risk of ischaemic stroke and myocardial infarction
We investigated whether pregnancy loss increases the risk of arterial thrombosis in young women. Women (age 18–50 years) with ischaemic stroke (IS) or myocardial infarction (MI) and at least one pregnancy were compared for pregnancy loss in a control group. Odds ratios (OR) with 95% confidence intervals (CI), adjusted for matching variables, cardiovascular risk factors, cardiovascular family history and the presence of antiphospholipid antibodies, were calculated for the number of pregnancy losses as well as the type of unsuccessful pregnancy (early miscarriage, late miscarriage and stillbirth). 165 IS cases, 218 MI cas...
Source: British Journal of Haematology - April 6, 2016 Category: Hematology Authors: Alberto Maino, Bob Siegerink, Ale Algra, Ida Martinelli, Flora Peyvandi, Frits R. Rosendaal Tags: Research Paper Source Type: research

Clinical and Radiological Features of Antiphospholipid Antibody Syndrome Associated with Stroke (P3.266)
Conclusions:aPLS associated strokes are predominantly perisylvian in location in the territory of MCA branches. The clinical and radiological features are similar to cardioembolic strokes.aPLS testing should be considered in all young patients with suggestive clinical and radiological features in addition to cardiac work up.Disclosure: Dr. Khayat has nothing to disclose. Dr. Alkully has nothing to disclose. Dr. Milyani has nothing to disclose. Dr. Almekhlafi has nothing to disclose. Dr. Alshanqiti has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Khayat, A., Alkully, H., Milyani, H., Almekhlafi, M., Alshanqiti, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research

Antiplatelet and Anticoagulant Agents for Secondary Prevention of Thromboembolic Events in People With Antiphospholipid Syndrome Cochrane Corner
Source: Stroke - February 26, 2018 Category: Neurology Authors: Malgorzata M. Bala, Magdalena Celinska-Lowenhoff, Wojciech Szot, Agnieszka Padjas, Mateusz Kaczmarczyk, Mateusz J. Swierz, Anetta Undas Tags: Secondary Prevention, Anticoagulants, Meta Analysis, Cerebrovascular Disease/Stroke Cochrane Corner Source Type: research

Ischemic stroke in a young woman with anti-phosphatidylserine/prothrombin (aPS/PT) complex antibody: a case report
We report an ischemic stroke patient using an oral contraceptive with aPS/PT complex antibody.
Source: Journal of the Neurological Sciences - December 7, 2018 Category: Neurology Authors: Kenichi Todo, Yasutaka Murakami, Masaya Togo, Tomoyuki Kono, Hajime Yoshimura, Taku Hoshi, Michi Kawamoto, Nobuo Kohara Tags: Letter to the Editor Source Type: research

High prevalence of inherited thrombophilia and antiphospholipid syndrome in myocardial infarction with non-obstructive coronary arteries: Comparison with cryptogenic stroke
A role of thrombophilia in myocardial infarction with non-obstructive coronary arteries (MINOCA) is unclear. We investigated thrombophilic factors in MINOCA patients versus those following cryptogenic stroke (CS), a well-established indication for thrombophilia screening.
Source: International Journal of Cardiology - May 17, 2019 Category: Cardiology Authors: Konrad Stepien, Karol Nowak, Ewa Wypasek, Jaroslaw Zalewski, Anetta Undas Source Type: research

COVID-19 and ischemic stroke: Should we systematically look for lupus anticoagulant and antiphospholipid antibodies?
Authors: Aubignat M, Godefroy O PMID: 32409176 [PubMed - as supplied by publisher]
Source: Revue Neurologique - May 17, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

COVID-19 and ischemic stroke: a systematic review and meta-summary of the literature
We report the pooled incidence of AIS in COVID-19 patients to be 1.2%, with a high mortality rate. Elevatedd-dimer, fibrinogen and the presence of antiphospholipid antibodies appear to be prominent in COVID-19 patients with concomitant AIS, but further mechanistic studies are required to elucidate their role in pathogenesis.
Source: Journal of Thrombosis and Thrombolysis - July 12, 2020 Category: Hematology Source Type: research

Antiphospholipid Syndrome-induced Ischemic Stroke Following Pembrolizumab: case report and systematic review
We report a case of a patient treated with pembrolizumab who developed an acute ischemic stroke (AIS) as manifestation of immunotherapy-induced antiphospholipid syndrome (APS) and provide a systematic review of the literature.
Source: Lung Cancer - August 3, 2021 Category: Cancer & Oncology Authors: Vito Tota, Marie Dagonnier, Didier Wery, Laure Binet, Nathalie Nagy, Val érie Durieux, Marie Diaz, Jose-Antonio Elosegi, Stéphane Holbrechts Tags: Review Source Type: research

A novel aGAPSS-based nomogram for the prediction of ischemic stroke in patients with antiphospholipid syndrome
ConclusionAge, diabetes, hyperuricemia, the platelet count, and the aGAPSS were risk factors for IS in patients with APS. The aGAPSS-IS may be a good tool for IS risk stratification for patients with APS based on routinely available data.
Source: Frontiers in Immunology - July 29, 2022 Category: Allergy & Immunology Source Type: research

Moyamoya Syndrome Presenting with Ischemic Stroke Caused by Rapid Worsening of Vessel Stenosis Associated with Triple-seropositive Antiphospholipid Syndrome: A Case Report
Intern Med. 2022 Aug 10. doi: 10.2169/internalmedicine.9316-22. Online ahead of print.ABSTRACTSeveral case reports of patients with both moyamoya syndrome (MMS) and antiphospholipid syndrome (APS) have been published. However, the relationship between MMS and APS has not been clarified. We herein report a patient with MMS who had an ischemic stroke with rapid worsening of stenosis of the middle cerebral artery associated with APS. The patient was triple-positive for antiphospholipid antibodies. Patients with MMS complicated by APS should be closely followed up with vascular imaging.PMID:35945020 | DOI:10.2169/internalmedicine.9316-22
Source: Internal Medicine - August 9, 2022 Category: Internal Medicine Authors: Kazumasa Oura Takashi Yamaguchi Taro Suzuki Mao Yamaguchi Oura Ryo Itabashi Tetsuya Maeda Source Type: research