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Correlation between fetal heart rate evolution patterns and magnetic resonance imaging findings in severe cerebral palsy: a longitudinal study
CONCLUSION: BGT-dominant brain damage accounted for 3/4 of the cases of CP in term or near-term infants, even in prenatal onset cases. Hypoxic-ischaemic insult has a major impact on CP development during the antenatal period.PMID:35007405 | DOI:10.1111/1471-0528.17089
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 10, 2022 Category: OBGYN Authors: Masahiro Nakao Yukiko Nanba Asumi Okumura Junichi Hasegawa Satoshi Toyokawa Kiyotake Ichizuka Naohiro Kanayama Shoji Satoh Nanako Tamiya Akihito Nakai Keiya Fujimori Tsugio Maeda Hideaki Suzuki Mitsutoshi Iwashita Akira Oka Tomoaki Ikeda Source Type: research

Bacteriological and therapeutic features of lung abscess
Conclusion: The identification of the responsible bacteria in lung abcess remains difficult. Management is based mainly on antibiotics wich is often probabilistic, in some cases associated with physiotherapy, percutaneous scan-guided drainage or rarely surgery.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Kallel, N., khemakhem, R., Abdelmouleh, K., Moussa, N., Yangui, I., Kammoun, S. Tags: Respiratory infections Source Type: research

Robot-Assisted Therapy in Upper Extremity Hemiparesis: Overview of an Evidence-Based Approach
Conclusion Robotic therapy has matured and represents an embodiment of a paradigm shift in neurorehabilitation following a stroke: instead of focusing on compensation, it affords focus in ameliorating the impaired limb in line with concepts of neuroplasticity. This technology-based treatment provides intensity, interactivity, flexibility, and adaptiveness to patient's performance and needs. Furthermore, it increases the productivity of rehabilitation care. Of course, efficiency must be discussed within a local perspective. For example, following the cost containment shown in the VA ROBOTICS study (46), the UK Nati...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Motor Abilities in Adolescents Born Preterm Are Associated With Microstructure of the Corpus Callosum
Conclusions: Impairments in motor abilities are present in preterm born adolescents without major neuromotor impairment and in the absence of focal brain injury. Altered microstructure of the corpus callosum microstructure appears a crucial factor, in particular for movement quality. Introduction Very preterm birth (birth <32 weeks of gestation) is associated with high risk of impaired neurodevelopment. Rates of severe neuromotor impairment, i.e., Cerebral Palsy (CP), are decreasing, in particular in those preterm children born with moderately low and very low birth weight (1). However, in a substantial propo...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Corticospinal Tract Integrity and Long-Term Hand Function Prognosis in Patients With Stroke
Conclusions: The present study showed that CST integrity (at 6 months after onset) in patients with chronic stroke was related to functional hand status. In addition, the mid-pons FA value was more predictive of functional restoration of the hand than the FN or FA value at the pontomedullary junction. These results may be useful in predicting the functional restoration of the hand and understanding the functional prognosis of stroke. Introduction Restoration of hand function is one of the most important goals for patients with stroke (1). Thus, techniques that aid in predicting restoration of hand function are also i...
Source: Frontiers in Neurology - April 14, 2019 Category: Neurology Source Type: research

Thalamic diaschisis following perinatal stroke is associated with clinical disability
ConclusionBilateral thalamic volume changes occur after perinatal stroke. Ipsilesional volume loss is not associated with clinical motor function. Contralesional volume is inversely correlated with clinical motor function, suggesting the thalamus is involved in the known developmental plasticity that occurs in the contralesional hemisphere after early unilateral injury.
Source: NeuroImage: Clinical - January 5, 2019 Category: Radiology Source Type: research

Long term motor function after neonatal stroke: Lesion localization above all
In conclusion, CP in childhood was closely linked to the location of the infarct in the motor system. Hum Brain Mapp, 2015. © 2015 Wiley Periodicals, Inc.
Source: Human Brain Mapping - September 10, 2015 Category: Neurology Authors: Mickael Dinomais, Lucie Hertz‐Pannier, Samuel Groeschel, Stéphane Chabrier, Matthieu Delion, Béatrice Husson, Manoelle Kossorotoff, Cyrille Renaud, Sylvie Nguyen The Tich, Tags: Research Article Source Type: research

Neonatal neuroimaging predicts recruitment of contralesional corticospinal tracts following perinatal brain injury
AimUnilateral perinatal brain injury may result in recruitment of ipsilateral projections originating in the unaffected hemisphere and development of unilateral spastic cerebral palsy (USCP). The aim of this study was to assess the predictive value of neonatal neuroimaging following perinatal brain injury for recruitment of ipsilateral corticospinal tracts. MethodNeonatal magnetic resonance imaging (MRI) and cranial ultrasound scans of 37 children (20 males, 17 females; median [range] gestational age 36 wks+4 [26+6–42wks+5] and birthweight 2312 g ([770–5230g]) with unilateral perinatal arterial ischaemic stroke (n=23) ...
Source: Developmental Medicine and Child Neurology - May 6, 2013 Category: Child Development Authors: Niek E Aa, Cornelia H Verhage, Floris Groenendaal, R Jeroen Vermeulen, Stella Bode, Onno Nieuwenhuizen, Linda S Vries Tags: Original Article Source Type: research

Structural Neuroplastic Change After Constraint-Induced Movement Therapy in Children With Cerebral Palsy
Research from the present laboratory with adult stroke patients showed that structural neuroplastic changes are correlated with clinical improvements due to constraint-induced movement (CI) therapy. This pilot study evaluated whether comparable changes occur in children receiving CI therapy. Ten children (6 boys) with congenital hemiparesis (mean age: 3 years, 3 months) underwent MRI scans 3 weeks before, immediately before, and immediately after receiving 3 weeks of CI therapy. Longitudinal voxel-based morphometry was performed on MRI scans to determine gray matter change. In addition, the Pediatric Motor Activity Log-Rev...
Source: PEDIATRICS - May 1, 2013 Category: Pediatrics Authors: Sterling, C., Taub, E., Davis, D., Rickards, T., Gauthier, L. V., Griffin, A., Uswatte, G. Tags: Case Report Source Type: research