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Condition: Cerebral Palsy

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Total 550 results found since Jan 2013.

Gait analysis patterns and rehabilitative interventions to improve gait in persons with hereditary spastic paraplegia: a systematic review and meta-analysis
ConclusionKnee hyperextension, non-sagittal pelvic movements, and reduced ROM at the knee, ankle, and hip represent the most peculiar patterns in HSP, compared to diplegic cerebral palsy and stroke. Botulinum improved comfortable gait velocity after 2 months. Nonetheless, interventions reducing spasticity might result in ineffective functional outcomes unveiling weakness. Intensive active physical therapy and FES might improve gait velocity in the very short term.
Source: Frontiers in Neurology - September 20, 2023 Category: Neurology Source Type: research

Safety, tolerability and feasibility of remotely-instructed home-based transcranial direct current stimulation in children with cerebral palsy
Perinatal stroke or brain bleeds affect an estimated 1 in 3500 births in the United States, with an increased risk of developing cerebral palsy (CP), a developmental disorder associated with motor impairment [1,2]. While many CP rehabilitation approaches emphasize behavioral repetition to improve gait and upper extremity function, these therapies are costly, restricted to the clinic, and may offer limited functional gains [3]. Therefore, innovative rehabilitation strategies which are accessible, cost-effective, and time-efficient are indicated for long-term benefits.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 29, 2023 Category: Neurology Authors: Preston Christopher, Ellen Sutter, Marissa Gavioli, Daniel H. Lench, Gwendolyn Nytes, Veronika Mak, Emma A. Simpson, Chrysanthy Ikonomidou, Melissa A. Villegas, Catarina Saiote, Bernadette T. Gillick Source Type: research

Umbilical Cord Milking in Nonvigorous Infants: A Cluster-Randomized Crossover Trial
Approximately 6 million infants each year require resuscitation at birth. Requiring this intervention is associated with higher risk of hypoxic-ischemic encephalopathy (HIE), cerebral palsy, attention-deficit or hyperactive disorder, autism, neonatal stroke, and death. In infants needing resuscitation, optimal cord management is essential to enhance placental transfusion. Delayed cord clamping (DCC) is used to enable placental transfusion in vigorous infants, but in nonvigorous infants—those who are limp, pale, or have minimal or no breathing—early cord clamping (ECC) is recommended. Another intervention for nonvigorou...
Source: Obstetrical and Gynecological Survey - August 1, 2023 Category: OBGYN Tags: OBSTETRICS: NEONATAL COMPLICATIONS Source Type: research

Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis
ConclusionsMore research is needed to study health issues in adults with MD. Adults with CP or SB deal with a variety of health issues. More attention for the mental health of these adults is needed. There also is a need for accessible and adequate screening, preventive measures and clinical follow-up.
Source: Frontiers in Neurology - July 18, 2023 Category: Neurology Source Type: research

Neuromuscular Electrical Stimulation for Children With Stroke
Research into neuromuscular electrical stimulation (NMES) for children with cerebral palsy and children post-stroke is limited. However, a recent review suggests that evidence for NMES is sufficient for improvement of gait and muscle strength as well as hand function and walking speed when combined with botulinum toxin and task-specific training.1 NMES is also referred to as electrical stimulation (eStim), functional electrical stimulation (FES), or muscle stimulation.
Source: Archives of Physical Medicine and Rehabilitation - July 11, 2023 Category: Rehabilitation Tags: Information/Education Page Source Type: research

Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns
Cell Mol Neurobiol. 2023 Jun 25. doi: 10.1007/s10571-023-01377-x. Online ahead of print.ABSTRACTBone marrow-derived mononuclear cells (BMMNCs) have been used for decades in preclinical and clinical studies to treat various neurological diseases. However, there is still a knowledge gap in the understanding of the underlying mechanisms of BMMNCs in the treatment of neurological diseases. In addition, prerequisite factors for the efficacy of BMMNC administration, such as the optimal route, dose, and number of administrations, remain unclear. In this review, we discuss known and unknown aspects of BMMNCs, including the cell ha...
Source: Cellular and Molecular Neurobiology - June 25, 2023 Category: Cytology Authors: Quyen Thi Nguyen Liem Nguyen Thanh Van T Hoang Trang T K Phan Michael Heke Duc M Hoang Source Type: research

Sensors, Vol. 23, Pages 5017: A Serious Game for the Assessment of Visuomotor Adaptation Capabilities during Locomotion Tasks Employing an Embodied Avatar in Virtual Reality
acqua Domenico Buongiorno The study of visuomotor adaptation (VMA) capabilities has been encompassed in various experimental protocols aimed at investigating human motor control strategies and/or cognitive functions. VMA-oriented frameworks can have clinical applications, primarily in the investigation and assessment of neuromotor impairments caused by conditions such as Parkinson’s disease or post-stroke, which affect the lives of tens of thousands of people worldwide. Therefore, they can enhance the understanding of the specific mechanisms of such neuromotor disorders, thus being a potential biomarker...
Source: Sensors - May 24, 2023 Category: Biotechnology Authors: Vladimiro Suglia Antonio Brunetti Guido Pasquini Mariapia Caputo Tommaso Maria Marvulli Elena Sibilano Sara Della Bella Paola Carrozza Chiara Beni David Naso Vito Monaco Giovanna Cristella Vitoantonio Bevilacqua Domenico Buongiorno Tags: Article Source Type: research

Linking cortex and contraction —Integrating models along the corticomuscular pathway
Computational models of the neuromusculoskeletal system provide a deterministic approach to investigate input-output relationships in the human motor system. Neuromusculoskeletal models are typically used to estimate muscle activations and forces that are consistent with observed motion under healthy and pathological conditions. However, many movement pathologies originate in the brain, including stroke, cerebral palsy, and Parkinson’s disease, while most neuromusculoskeletal models deal exclusively with the peripheral nervous system and do not incorporate models of the motor cortex, cerebellum, or spinal cord. An integr...
Source: Frontiers in Physiology - May 10, 2023 Category: Physiology Source Type: research

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Effects of functional electrical stimulation cycling combined with arm cranking exercise on cardiorespiratory fitness in people with central nervous system disorders: a systematic review and meta-analysis
CONCLUSIONS: Hybrid FES cycling produced higher VO2peak compared to ACE or FES cycling during acute bouts of exercise. Hybrid FES cycling can improve cardiorespiratory fitness in people with a SCI. Additionally, there is emerging evidence that hybrid FES cycling might increase aerobic fitness in people with mobility disability related to CNS disorders.PMID:37098358 | DOI:10.1016/j.apmr.2023.03.026
Source: Health Physics - April 25, 2023 Category: Physics Authors: Suzanne M áté Canan Sinan-Fornusek Prakash Dhopte Maria Fiatarone Singh Daniel Hackett Ch é Fornusek Source Type: research

Primary healthcare needs and service utilisation of people with disability: a data linkage protocol
Introduction General practitioners (GPs) play a crucial role in the early management and treatment of the comorbidities and complications experienced by people with disability. However, GPs experience multiple constraints, including limited time and disability-related expertise. Knowledge gaps around the health needs of people with disability as well as the frequency and extent of their engagement with GPs mean evidence to inform practice is limited. Using a linked dataset, this project aims to enhance the knowledge of the GP workforce by describing the health needs of people with disability. Methods and analysis This pro...
Source: BMJ Open - April 19, 2023 Category: General Medicine Authors: Douglas, J., Winkler, D., McLeod, A., Oliver, S., Gardner, K., Supple, J., Pearce, C. Tags: Open access, Health services research Source Type: research

Effect of backward and forward walking on lower limb strength, balance, and gait in multiple sclerosis: a randomized feasibility trial - DelMastro HM, Ruiz JA, Simaitis LB, Gromisch ES, Neto LO, Cohen ET, Wong E, Krug RJ, Lo AC.
We examined the feasibility of a BW intervention...
Source: SafetyLit - March 20, 2023 Category: International Medicine & Public Health Tags: Egress, Escape, Evacuation, Crowds Source Type: news

BCI-activated electrical stimulation in children with perinatal stroke and hemiparesis: A pilot study
ConclusionBrain computer interface-FES was well -tolerated and feasible in children with hemiparesis. This paves the way for clinical trials to optimize approaches and test efficacy.
Source: Frontiers in Human Neuroscience - March 17, 2023 Category: Neuroscience Source Type: research