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Condition: Patent Foramen Ovale

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Total 1415 results found since Jan 2013.

Patent foramen ovale leading to mismanagement in a mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke ‐like episodes patient
We report the clinical, imaging, echocardiography and muscle biopsy findings of a patient presenting by unique characteristics which have not been reported in previous cases of MELAS. The reported case is a 34  year old man with the history of three times hospitalization due to muscle weakness, encephalopathy, progressive cognitive decline, and gradual visual loss. Muscle biopsy revealed Ragged Red Fibers concomitant with mitochondrial disorders. PFO was found in echocardiography leading to mismanagemen t of this patient and MR imaging showed ischemic lesions with a progressive pattern. This is the first reported case of...
Source: Clinical Case Reports - July 21, 2023 Category: General Medicine Authors: Mehri Salari, Masoud Etemadifar, Ronak Rashedi, Romina Rashedi Tags: CASE REPORT Source Type: research

Survey on APS diagnosis and antithrombotic treatment in patients with ischaemic stroke, other brain ischaemic injury or arterial thromboembolism in other sites: Communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies (LA/aPL)
CONCLUSIONS: Much of the variation in practice reflects the lack of evidence-based recommendations. The survey results should inform the development of a more uniform multidisciplinary consensus approach to diagnosis and antithrombotic treatment.PMID:37391096 | DOI:10.1016/j.jtha.2023.06.020
Source: Thrombosis and Haemostasis - June 30, 2023 Category: Hematology Authors: Hannah Cohen David J Werring Arvind Chandretheva Prabal Mittal Katrien M J Devreese David A Isenberg ISTH SSC LA/aPL Subcommittee Study Group Source Type: research

Inadvertent misplacement of pacemaker lead presented with acute ischemic stroke
AbstractIf a permanent pacemaker lead is misplaced in the left ventricle (LV), the lead may interfere with normal functioning of the heart leading various complications, including heart rhythm problems and blood clots. In our case, the LV lead that passed through the patent foramen ovale and was misplaced into the LV was detected in a 78-year-old patient who presented with embolic stroke. Thrombus regression was achieved with anticoagulation, and then the lead extraction was planned. The lead extraction is a priority in acute cases; but it is not the primary approach in long-term leads that were misplaced into the LV. A pa...
Source: Pacing and Clinical Electrophysiology : PACE - June 28, 2023 Category: Cardiology Authors: Almina Erdem, Akin Torun, Şahhan Kılıç, Tufan Cinar, Mehmet Uzun, Ahmet Lütfullah Orhan Tags: CASE REPORT Source Type: research

Transcranial Doppler Screening for Patent Foramen Ovale Closure in Cryptogenic Strokes in Young: A Single Center Experience from South India
CONCLUSIONS: R-L shunt is common in cryptogenic ischemic strokes in young. TCD with bubble contrast study is a noninvasive and feasible bedside tool to detect them. Applying the ESUS criteria in these cryptogenic strokes with a positive TCD bubble contrast study can be then used for selecting patients for more invasive tests like TEE. High-risk PFOs picked up with TEE can be then considered for PFO closure for secondary stroke prevention. The history of Valsalva maneuver-like activity (such as lifting heavy weights or straining) at the time of stroke onset can be a clinical predictor for the presence of an R-L shunt. In ad...
Source: Journal of the Association of Physicians of India - June 25, 2023 Category: General Medicine Authors: Deepti Bal Atif Iqbal Ahmed Shaikh Murali Rayani Sanjith Aaron Viji Samuel Thompson John Jose Jesu Krupa Rohit Ninan Benjamin Joanne Lydia Rajkumar Appaswamy Thirumal Prabhakar Source Type: research

Synchronous multimode ultrasound for assessing right-to-left shunt: a prospective clinical study
ConclusionSynchronous multimodal ultrasound significantly improves the detection rate and test efficiency, quantifies RLS more accurately, and reduces testing risks and medical costs. We conclude that synchronous multimodal ultrasound has significant potential for clinical applications.
Source: Frontiers in Neurology - June 20, 2023 Category: Neurology Source Type: research

Patent foramen ovale closure with the Occlutech Figulla flex II device: A long-term (up to 10-years) follow-up
Percutaneous closure represents the first line of treatment In patients with cryptogenic stroke and documented patent foramen ovale (PFO). Scarce data report the long-term outcomes of patients undergoing PFO closure with the Figulla Flex II device (Occlutech, Germany).
Source: International Journal of Cardiology - June 8, 2023 Category: Cardiology Authors: Daniela Trabattoni, Sebastiano Gili, Giuseppe Calligaris, Giovanni Teruzzi, Sarah Troiano, Paolo Ravagnani, Giulia Santagostino Baldi, Piero Montorsi Source Type: research

The Intriguing Links Among Patent Foramen Ovale, Patent Foramen Ovale Closure, and the Risk for Heart Failure
Exercise intolerance is the central symptom of heart failure (HF). In the growing subset of patients who have HF with preserved ejection fraction (HFpEF), three main hemodynamic mechanisms accounting for limited exercise capacity have been identified1,2: (1) chronotropic incompetence, or the inability to achieve an appropriate increase in heart rate during exertion; (2) an excessive rise in pulmonary capillary pressure during exercise; and (3) reduced stroke volume reserve or cardiac output reserve.
Source: Journal of the American Society of Echocardiography - May 18, 2023 Category: Cardiology Authors: Rajeev C. Mohan, Sheldon E. Litwin Tags: Editorial Comment Source Type: research

Patent foramen ovale closure in non-elderly and elderly patients with cryptogenic stroke: a hospital-based cohort study
DiscussionPFO closure was associated with a reduced risk of the primary outcome in patients with PFO and CS in our total cohort, which included non-elderly and elderly patients. Compared to those without PFO closure, elderly patients with PFO closure had a better functional outcome at 180 days. PFO closure might be considered in selected elderly patients with PFO.
Source: Frontiers in Neurology - May 16, 2023 Category: Neurology Source Type: research

Pearls and Pitfalls in the Transesophageal Echocardiographic Diagnosis of Patent Foramen Ovale
Large randomized controlled trials have shown the benefits of percutaneous closure of patent foramen ovale (PFO) in patients with cryptogenic stroke and PFO. Recent studies have highlighted the clinical significance and prognostic implication of various anatomical features of PFO and the adjacent atrial septum, such as atrial septal aneurysm (ASA), PFO size, large shunt, and hypermobility. Transthoracic echocardiography with contrast study is used for the indirect diagnosis of PFO, as it reveals the passage of the contrast into the left atrium.
Source: Journal of the American Society of Echocardiography - May 15, 2023 Category: Cardiology Authors: Jae-Kwan Song Tags: Review Articles Source Type: research

Reply to ‘patent foramen ovale device closure for patients with stroke and high-risk PFO morphology’
Source: Heart and Vessels - May 14, 2023 Category: Cardiology Source Type: research

Patent foramen ovale device closure for patients with stroke and high-risk PFO morphology
Source: Heart and Vessels - May 14, 2023 Category: Cardiology Source Type: research

Changes in cerebral autoregulation, stroke-related blood biomarkers, and autonomic regulation after patent foramen ovale closure in severe migraine patients
CONCLUSION: Patent foramen ovale closure can improve dCA and alter elevated arterial PDGF-BB levels in migraine patients with PFO, both of which may be related to the preventive effect of PFO closure on stroke occurrence/recurrence.PMID:37157233 | DOI:10.1111/cns.14244
Source: CNS Neuroscience and Therapeutics - May 9, 2023 Category: Neuroscience Authors: Zhen-Ni Guo Yang Qu Yongsheng Gao Yingqi Xing Hongyin Ma Jia Liu Yu-Zhu Guo Junlei Chang Peng Zhang Hang Jin Xin Sun Ke Han Han-Hwa Hu Qianyan He David Martin Simpson Yi Yang Source Type: research