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Condition: Hemorrhagic Stroke
Cancer: Brain Cancers

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Total 297 results found since Jan 2013.

Didymin Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the PPAR Signaling Pathway
CONCLUSION: Didymin protected neuron cells against IR injury in vitro and in vivo by activation of the PPAR pathway. Didymin may be a candidate drug for IR treatment.PMID:36168249 | PMC:PMC9520049 | DOI:10.3349/ymj.2022.0040
Source: Yonsei Medical Journal - September 28, 2022 Category: Universities & Medical Training Authors: Qiang Li Hongting Zhang Xiumei Liu Source Type: research

E-152 Neurointervention in the pediatric population: 18-years experience from a single center
ConclusionsAt out institution, multidisciplinary interaction allowed the treatment of a wide variety of cerebrovascular diseases in the pediatric population. Pediatric patients carry high complication risks due to frequent presence of systemic conditions, but joined experience from pediatric neurology, neurosurgery and neurointervention departments allow their treatment with optimal planning and results.Abstract E-152 Table 1Intracranial aneurysms Variable Value Age at diagnosis, mean (SD) or median (IQR) 16 (16–19) Male:Female 12:10 Associated conditions•Moya moya•Connective tissue disorder•Von Wille...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Donnelly, B., Monteiro, A., Recker, M., Khawar, W., Waqas, M., Cappuzzo, J., Reynolds, R., Siddiqui, A., Levy, E. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Inflammation and Severe Cerebral Venous Thrombosis
This study reviews the current literature regarding the involvement of inflammation in the pathophysiology and anti-inflammatory interventions of severe CVT, which would contribute to informing the pathophysiology mechanism and laying a foundation for exploring novel severe CVT therapeutic strategies.
Source: Frontiers in Neurology - July 22, 2022 Category: Neurology Source Type: research

Successful treatment of an 82-year-old COVID-19 delta variant-infected patient with haemorrhagic stroke and active prostate cancer brain metastasis
Clin Transl Discov. 2022 Mar;2(1):e20. doi: 10.1002/ctd2.20. Epub 2022 Jan 12.NO ABSTRACTPMID:35464128 | PMC:PMC9015616 | DOI:10.1002/ctd2.20
Source: Clinical Prostate Cancer - April 25, 2022 Category: Cancer & Oncology Authors: Buhai Wang Jiangquan Yu Yichun Zeng Xian Zhang Chongxu Han Qili Lu Xiaolin Wang Yichen Liang Juan J Gu Yusheng Shu Source Type: research

Therapeutic effect of anti-HMGB1 antibody in a mouse model of 4-h middle cerebral artery occlusion: comparison with tissue plasminogen activator
Conclusion These results indicate that αHMGB1 antibody may be therapeutically efficient in the delayed phase of ischemia, where tPA treatment is no longer an eligible option. Treatment with an αHMGB1 antibody may be an effective therapeutic option in patients who exceed the tPA therapeutic time window.
Source: NeuroReport - April 24, 2022 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research

Non-coding RNAs in the regulation of blood –brain barrier functions in central nervous system disorders
AbstractThe blood –brain barrier (BBB) is an essential component of the neurovascular unit that controls the exchanges of various biological substances between the blood and the brain. BBB damage is a common feature of different central nervous systems (CNS) disorders and plays a vital role in the pathogenesis of t he diseases. Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNA (lncRNAs), and circular RNAs (circRNAs), are important regulatory RNA molecules that are involved in almost all cellular processes in normal development and various diseases, including CNS diseases. Cumulative evi dences hav...
Source: Fluids and Barriers of the CNS - March 26, 2022 Category: Neuroscience Source Type: research

Diagnostic accuracy of major stroke types in Chinese adults: A clinical adjudication study involving 40,000 stroke cases
Lancet Reg Health West Pac. 2022 Mar 5;21:100415. doi: 10.1016/j.lanwpc.2022.100415. eCollection 2022 Apr.ABSTRACTBACKGROUND: Widespread use of brain imaging in suspected stroke cases in Chinese adults has prompted the need for clinical adjudication studies of stroke types. We conducted a clinical adjudication study to assess the reporting and diagnostic accuracy of major stroke types.METHODS: The prospective China Kadoorie Biobank recruited >512,000 adults (mean age 52 years, 59% women) from 10 urban and rural areas in China during 2004-2008, and recorded 45,859 first-ever incident stroke cases during an 11-year follow...
Source: Cancer Control - March 14, 2022 Category: Cancer & Oncology Authors: Iain Turnbull Robert Clarke Neil Wright Yu Guo Christina Kartsonaki Pei Pei Alex Hacker Canqing Yu Simon Gilbert Ling Yang Jinyi Zhou Sam Sansome Jun Lv Liming Li Zhengming Chen Yiping Chen Source Type: research

Stroke Mimics in the Acute Setting: Role of Multimodal CT Protocol ADULT BRAIN
CONCLUSIONS: Multimodal CT demonstrated low sensitivity but high specificity in the diagnosis of stroke mimics in the acute setting. The high specificity of multimodal CT allows ruling out stroke and thereby avoiding unnecessary revascularization treatment in patients with diagnosis of a stroke mimic.
Source: American Journal of Neuroradiology - February 4, 2022 Category: Radiology Authors: Prodi, E., Danieli, L., Manno, C., Pagnamenta, A., Pravata, E., Roccatagliata, L., Städler, C., Cereda, C. W., Cianfoni, A. Tags: ADULT BRAIN Source Type: research

Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders
CONCLUSIONS: Delirium is a common complication of neurological diseases, and it can coexist with catatonia. The recognition of catatonic delirium has clinical significance in terms of etiology, as it was significantly associated with viral and anti-NMDAR encephalitis.PMID:35040665 | DOI:10.1176/appi.neuropsych.18120364
Source: Journal of Neuropsychiatry and Clinical Neurosciences - January 18, 2022 Category: Psychiatry Authors: Jesus Ramirez-Bermudez Angela Medina-Gutierrez Heraclides Gomez-Cianca Patricia Arias Andres P érez-Gonzalez Paulina Ang élica Lebrija-Reyes Mariana Espinola-Nadurille Luis Carlos Aguilar-Venegas Carmen Ojeda-L ópez Miguel Restrepo-Mart ínez Leo Bayli Source Type: research