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Cancer: Squamous Cell Carcinoma

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Total 86 results found since Jan 2013.

Association of Cancer Cell Type and Extracellular Vesicles With Coagulopathy in Patients With Lung Cancer and Stroke Brief Report
Conclusions—Our findings indicate that cancer cell type is associated with circulating EV levels and coagulopathy in patients with lung cancer and stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Jong-Won Chung, Yeon Hee Cho, Myung-Ju Ahn, Mi Ji Lee, Gyeong-Moon Kim, Chin-Sang Chung, Oh Young Bang Tags: Biomarkers, Mechanisms, Translational Studies, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research

Recurrent Stroke Due to Metastatic Pulmonary Tumor Emboli as an Important Clinical Entity
We present an autopsy case of repetitive stroke due to tumor emboli, indistinguishable from thromboembolism with a hypercoagulable state in its clinical course. A 72-year-old man diagnosed with stage IVA oropharyngeal squamous cell carcinoma received chemoradiotherapy. Follow-up imaging revealed mediastinal lymph nodes and pulmonary metastasis. One year later, the patient experienced right arm weakness, and brain magnetic resonance imaging showed acute ischemic lesions in multiple vascular territories.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2017 Category: Neurology Authors: Junji Takasugi, Manabu Sakaguchi, Naoki Oyama, Yasufumi Gon, Yasukazu Terasaki, Tsutomu Sasaki, Susumu Nakahara, Kenji Ohshima, Yumiko Hori, Eiichi Morii, Hideki Mochizuki Tags: Case Studies Source Type: research

Stroke death in patients receiving radiation for head and neck cancer in the modern era
ConclusionsWhile radiotherapy for head and neck cancer increases the hazard of stroke death, this is reduced in the modern era and remains a very small absolute risk.
Source: Frontiers in Oncology - June 15, 2023 Category: Cancer & Oncology Source Type: research

Squamous Cell Carcinoma of the Neck: An Unlikely Stroke Mimic
Stroke mimics are noncerebrovascular conditions that present with classical stroke symptoms. They account for up to 30% of stroke presentations in the emergency department (ED). Emergency physicians are faced with a diagnostic dilemma —rapid treatment of stroke, a leading cause or mortality and morbidity in the United States, or ruling out the ever-growing list of conditions that mimic strokes.
Source: The Journal of Emergency Medicine - October 14, 2021 Category: Emergency Medicine Authors: Vera Obinwanne, Laura Bauler, Dylan Bergeon, Timothy Trichler Source Type: research

Risk of Stroke After Definitive Radiotherapy —Cause for Concern or Modest Risk?
With the rapidly increasing prevalence of oropharyngeal squamous cell carcinoma (OPSCC), largely driven by the human papillomavirus (HPV) epidemic, and with relative equipoise between radiation-based and surgery-based treatment protocols, there has been renewed interest in describing differences in functional outcomes between the 2 treatment modalities. Radiation is theoretically related to stroke risk due to carotid artery intimal injury, which could lead to the development of atherosclerosis. Both carotid artery stenosis and carotid intima-medial thickness have been shown to be associated with radiation therapy providing...
Source: JAMA Otolaryngology - Head and Neck Surgery - June 23, 2022 Category: ENT & OMF Source Type: research

Stroke after Radiotherapy for Head and Neck Cancer – What is the Risk?
Treating head and neck squamous cell carcinomas with radiotherapy has been shown to cause damage to the cerebrovasculature. This retrospective cohort study found that any exposure to radiation was associated with a 46% higher hazard of stroke, and with radiotherapy as the sole treatment modality, 70% increased risk of stroke compared to surgery alone. Implications of this research speak to the need for adequate follow-up and survivorship care among patients that were treated with RT.
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Source Type: research

Teaching NeuroImages: Radiation-associated symptomatic carotid artery disease with ipsilateral radiodermatitis
A 68-year-old man with a history of squamous cell carcinoma of the tongue treated with external beam radiation therapy in 2007 presented in 2013 with acute onset expressive aphasia and right lower facial weakness. MRI confirmed an acute infarct in the left frontal cortex. CT angiography revealed occlusion vs critical stenosis of the left internal carotid artery, new from 2007. Examination of the patient's neck revealed ipsilateral radiodermatitis (figure). Therapeutic neck irradiation has been associated with accelerated atheromatous disease, carotid artery stenosis, and increased risk of stroke.1,2 Ipsilateral radiodermat...
Source: Neurology - February 2, 2015 Category: Neurology Authors: Ehrlich, M. E., Gulvezan, T., Southerland, A. M. Tags: All Imaging, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC).
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Tags: Clinical Investigation Source Type: research

Up-front Surgery and Risk of Stroke in US Veterans With Oropharyngeal Carcinoma
This cohort study evaluates the association of up-front surgery and stroke risk compared with nonsurgical treatment for oropharyngeal squamous cell carcinoma among US veterans.
Source: JAMA Otolaryngology - Head and Neck Surgery - June 23, 2022 Category: ENT & OMF Source Type: research

Patients With Head/Neck Cancer See Lower Stroke Risk With Initial Surgery
(MedPage Today) -- In oropharyngeal squamous cell carcinoma (OPSCC), the type of initial treatment appears to influence the likelihood of stroke in the years afterward, researchers said. A population-based study of U.S. veterans treated for OPSCC...
Source: MedPage Today Radiology - August 12, 2022 Category: Radiology Source Type: news

A Case Series Of Non-Bacterial Thrombotic Endocarditis Associated With Gynecological Malignancies (P6.248)
Conclusions:NBTE is an important ischemic stroke mechanism. We have reported three cases where the underlying malignancy was gynecological (endometrial, ovarian, and cervical). In the first two cases, the malignancy was discovered during the investigations for the stroke mechanism, while the third had a known underlying malignancy. This series highlights the need to consider gynecological malignancies as an underlying cause of stroke in young women; and that the ischemic event can occur prior to the malignancy diagnosis.Disclosure: Dr. Schabas has nothing to disclose. Dr.Teal has received personal compensation for activiti...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Schabas, A., Teal, P., Yip, S., Mann, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Bm-12 * cerebral infarction secondary to pulmonary vein compression and left atrial appendage tumor infiltration as the presenting sign of metastatic squamous cell carcinoma of the base of the tongue
CONCLUSION: Cardiac metastases are rare and non-myxomatous tumor embolization to the brain even rarer especially in the setting of cerebral infarction due to pulmonary vein thrombus. Here we describe a case of multiple acute cerebral infarctions appearing from a proximal source refractory to anticoagulation. Thromboembolism from the pulmonary vein and tumor embolization from cardiac metastases are the likely mechanisms for his clinical presentation and radiographic findings. This case demonstrates the complexity of multiple stroke etiologies in one patient and the importance of cardiac imaging in stroke evaluation, particu...
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Dredla, B., Siegel, J., Jaeckle, K. Tags: BRAIN METASTASES (CLINICAL AND/OR LABORATORY RESEARCH) Source Type: research

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research