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Total 51 results found since Jan 2013.

Thrombolytic Treatment of Cardiac Myxoma-Induced Ischemic Stroke: a Review.
Abstract Primary cardiac tumors are uncommon, with an autopsy frequency of 0.001%-0.28%: 75% of them are benign, and 50-75% of these are myxomas. Often the first neurological manifestations of a cardiac myxoma include transient ischemic attacks and ischemic strokes. Although thrombolytic therapy represents the gold standard for acute ischemic stroke treatment, its safety and effectiveness in stroke patients with myxoma is unknown. From the analysis of the literature on thrombolysis in ischemic stroke patients with myxoma we report clinical evidence supporting the use of thrombolytics, and the application of thromb...
Source: Current Drug Safety - January 10, 2014 Category: Drugs & Pharmacology Authors: Acampa M, Guideri F, Tassi R, D'Andrea P, Marotta G, Giudice GL, Martini G Tags: Curr Drug Saf Source Type: research

Effect of Computed Tomography before Cardiac Surgery on Surgical Strategy, Mortality and Stroke
Conclusions Current evidence suggests that preoperative CT imaging may lead to decreased stroke and mortality rate in patients undergoing primary cardiac surgery by optimizing surgical approach. In patients undergoing redo cardiac surgery stroke rate is also decreased but the effect on mortality is unclear. However, evidence is weak and included studies were of moderate quality.
Source: European Journal of Radiology - January 16, 2016 Category: Radiology Source Type: research

Prolyl hydroxylase domain inhibitors: can multiple mechanisms be an opportunity for ischemic stroke?
Abstract Stroke and cerebrovascular disease are now the fifth most common cause of death behind other diseases such as heart, cancer and respiratory disease and accounts for approximately 40-50 fatalities per 100,000 people each year in the United States. Currently the only therapy for acute stroke, is intravenous administration of tissue plasminogen activator which was approved in 1996 by the FDA. Surprisingly no new treatments have come on the market since, although endovascular mechanical thrombectomy is showing promising results in trials. Recently focus has shifted towards a preventative therapy rather than t...
Source: Neuropharmacology - December 19, 2018 Category: Drugs & Pharmacology Authors: Lanigan SM, O'Connor JJ Tags: Neuropharmacology Source Type: research

A case report of left atrial myxoma-induced acute myocardial infarction and successive stroke
Rationale: Left atrial myxoma is a common primary cardiac tumor, however, due to poor image quality or atypical myxoma images, it is often misdiagnosed by echocardiograph. A case of left atrial myxoma being misdiagnosed as a thrombus, which successively caused acute myocardial infarction (AMI) and stroke, is very rare. Contrast-enhanced echocardiography can play an important role in definitive diagnosis. Patient concerns: A 44-year-old woman was diagnosed AMI because of chest pain with no significant stenosis in the coronary arteries. One month later, the patient was suddenly found unconscious, magnetic resonance imag...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Ischemic stroke and incidental finding of a right atrial lipoma
A young man presented with recurrent ischemic stroke under antiplatelet therapy. A patent foramen ovale (PFO) was diagnosed by transesophageal echocardiography (TEE) and the patient was referred to our institution for percutaneous closure. An echogenic mass in the right atrium was detected during the intraprocedural TEE. The interventional team decided to perform transcatheter closure of PFO under fluoroscopy and TEE guide, without complications. Subsequent cardiac magnetic resonance (CMR) imaging confirmed an encapsulated and hyperintense mass located in the roof of the right atrium. The signal intensity pattern and the a...
Source: Journal of Cardiovascular Medicine - November 5, 2013 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research

Mechanical endovascular procedure for the treatment of acute ischemic stroke caused by total detachment of a papillary fibroelastoma
Papillary fibroelastomas (PFEs) are rare cardiac tumors. Despite their benign nature, they are associated with a high risk of embolic complications including stroke. Endovascular treatment has been reported as a safe procedure in patients with myxoma, the most common type of primary cardiac tumor. A case of ischemic stroke due to embolization of a PFE successfully treated with a single pass of a retrievable stent is described. A 64-year-old patient with a right middle cerebral artery syndrome was treated with an intravenous and endovascular protocol as a revascularization procedure. Mechanical thrombectomy resulted in tota...
Source: Journal of NeuroInterventional Surgery - June 28, 2014 Category: Neurosurgery Authors: Tejada, J., Galiana, A., Balboa, O., Clavera, B., Redondo-Robles, L., Alonso, N., Magadan, V. Tags: Electronic pages Source Type: research

Aortic Valvular Papillary Fibroelastoma Leading to Acute Ischemic Stroke in a Pediatric Patient (P1.286)
Conclusions:Previously published cases of children with IS and PF have identified the mitral valve as the site of the PF. Our case demonstrates that aortic valvular PF can be associated with IS in pediatric patients. Resection of symptomatic PF is recommended to prevent further cardio-embolic strokes.Disclosure: Dr. Farooqui has nothing to disclose. Dr. Mannel has nothing to disclose. Dr. Silliman has received research support from Sanofi Genzyme, Biogen Idec, Bristol Myers and Novartis.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Farooqui, I., Mannel, R., Silliman, S. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Left Ventricular Myxoma Leading to Stroke: A Rare Case Report
We report the case of a 23-year-old man presenting with right hemiplegia and muscle strength degeneration under a diagnosis of stroke. Transthoracic echocardiography revealed a 29 × 26 mm mass arising from the anterior interventricular septum. The tumor was surgically removed, and histology confirmed the diagnosis of left ventricular myxoma. We report its clinical features and treatment to add to the current knowledge.
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Ischemic stroke induces cardiac dysfunction and alters transcriptome profile in mice
Stroke can induce cardiac dysfunction in the absence of primary cardiac disease; however, the mechanisms underlying the interaction between the neurological deficits and the heart are poorly understood. The ob...
Source: BMC Genomics - September 4, 2021 Category: Genetics & Stem Cells Authors: Jie Chen, Jiahong Gong, Haili Chen, Xuqing Li, Li Wang, Xiaoli Qian, Kecheng Zhou, Ting Wang, Songhe Jiang, Lei Li and Shengcun Li Tags: Research Source Type: research

Electrocardiographic abnormalities in acute cerebrovascular events in patients with/without cardiovascular disease
Conclusion: Ischemia-like ECG changes and arrhythmias are frequently seen in stroke patients, even in those with no history or signs of primary heart disease, which support a central nervous system origin of these ECG abnormalities. Further study is necessary to better define the brain-heart interaction.
Source: Annals of Indian Academy of Neurology - February 25, 2013 Category: Neurology Authors: Mansoureh ToghaAlireza SharifpourHaleh AshrafMansour MoghadamMohammad Ali Sahraian Source Type: research

Initial Experience With Minimally Invasive Surgical Exclusion of the Left Atrial Appendage With an Epicardial Clip
Conclusions: Isolated epicardial left atrial clipping is a safe treatment option in high-risk patients with AF. Long-term success in preventing stroke is still to be determined, but short-term results are very encouraging.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - January 1, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Cancers, Vol. 14, Pages 1111: Cardiac Myxomas Resembling Malignant Neoplasia: Incidentally Diagnosed vs. Cerebral Embolized Myxomas
Conclusions: After the surgical removal of CM, the outcome is compromised if preoperative cerebral embolization occurs. Surgical treatment is therefore indicated as soon as possible, especially when CM have a non-solid surface, are localized in the left heart, and have a pedunculated attachment away from the fossa ovalis.
Source: Cancers - February 22, 2022 Category: Cancer & Oncology Authors: Salem Hillmer Friedrich Panholzer Saad Salem Frank Ernst Maetzler Puehler Lutter Schoeneich Haneya Cremer Schoettler Tags: Article Source Type: research

Neurological complication related to atrial myxomas
Conclusions This case highlights both the recognised neurologic complications of atrial myxoma in a single patient and presents the characteristic angiographic findings. The diagnosis of cerebral aneurysms can be delayed up to five years1. Evaluation should therefore be considered following a histologic diagnosis of atrial myxoma.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Baird-Gunning, J., Lalloo, S., Lueck, C. J., Das, C. Tags: Abstracts Source Type: research

Cardiac myxoma: clinical characteristics, surgical intervention, intra-operative challenges and outcome.
CONCLUSION: The success rate after surgical removal of cardiac myxoma in this study was substantial and complications were rare. PMID: 28762298 [PubMed - as supplied by publisher]
Source: Perfusion - July 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Abu Abeeleh M, Saleh S, Alhaddad E, Alsmady M, Alshehabat M, Bani Ismail Z, Massad I, Bani Hani A, Abu Halaweh S Tags: Perfusion Source Type: research

β-Blocker therapy for cirrhotic cardiomyopathy: a randomized-controlled trial
Background Cirrhotic cardiomyopathy is characterized by an attenuated contractile response to stress. Long-term exposure of β-adrenergic receptors to persistently high levels of catecholamines has been implicated in its pathogenesis. We hypothesized that β-blockade with metoprolol could reverse the changes in heart function and morphology in cirrhotic cardiomyopathy. Patients and methods In this prospective randomized trial, we included 78 patients aged between 18 and 60 years with abnormal cardiac output response under dobutamine stress echocardiography, without primary cardiac disease or a history of alcohol intak...
Source: European Journal of Gastroenterology and Hepatology - July 6, 2018 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research