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Total 458 results found since Jan 2013.

A Serious Diagnosis Lacking Common Symptoms
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; & AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regi...
Source: The Case Files - May 28, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Secondary prevention advices after cardiovascular index event: From drug prescription to risk factors control in real world practice.
Authors: Faggiano P, Fattirolli F, Frisinghelli A, Piccioli L, Dasseni N, Silverii MV, Albricci L, D'Ambrosio G, Garrì R, Esposito L, Giallauria F Abstract The present study aims at evaluating the achievement of blood pressure, lipid and blood glucose targets, healthy lifestyle changes and appropriate drug prescription/adherence in patients attending secondary prevention/CR ambulatory visit after index cardiovascular event in a time period ranging 1 to 5 year. At ambulatory visit, a predetermined set of data collection was used, including demographic data, cardiovascular risk factors and lifestyle habits, type and...
Source: Monaldi Archives for Chest Disease - May 22, 2019 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Vestibular Migraine: How to Sort it Out and What to Do About it
Conclusions: The keys to correctly diagnosing VM is identifying a relationship between vestibular symptoms and migrainous features and being aware of the heterogeneity of manifestations of this enigmatic, but treatable, condition. The principles of treatment of VM include rescue therapy, lifestyle modification, nonpharmacologic migraine preventives, pharmacologic migraine prophylaxis, and treatment of comorbidities.
Source: Journal of Neuro-Ophthalmology - May 21, 2019 Category: Opthalmology Tags: Disease of the Year: Migraine Source Type: research

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Conclusions: Brown fat tissue is a normal variant in pediatric F-18 FDG studies. This diffuse activity can frustrate the radiologist reading the study and possibly cause a misdiagnosis. Propranolol may be a promising solution to reducing the brown fat in pediatric patients undergoing a F-18 FDG PET/CT scan. p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 16.0px Helvetica; -webkit-text-stroke: #000000} span.s1 {font-kerning: none} p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 16.0px Helvetica; -webkit-text-stroke: #000000} span.s1 {font-kerning: none}
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Beaird, B. Tags: Technologist Student Papers II Source Type: research

Prevent Osteoporotic Fractures With a Fracture Liaison Service
Imagine leaving the hospital after suffering a heart attack without being treated for hypertension or being started on a beta blocker. What would we think of the hospital where patients are never educated about the relationship between treating hypertension and reducing myocardial infarction and stroke risk? Unfortunately, this happens every day with osteoporosis and fractures... [Read More]
Source: The Rheumatologist - May 18, 2019 Category: Rheumatology Authors: Micah Yu, MD, Anna Lafian, DO, & Christina Downey, MD Tags: Conditions Osteoporosis osteoporotic fracture rates Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Admission Heart Rate Is a Determinant of Effectiveness of Beta-Blockers in Acute Myocardial Infarction Patients.
CONCLUSIONS: Admission HR might determine the efficacy of β-blockers for current AMI patients. PMID: 30930346 [PubMed - as supplied by publisher]
Source: Circulation Journal - March 29, 2019 Category: Cardiology Authors: Okuno T, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, K Tags: Circ J Source Type: research

Tachycardia: The hidden cardiovascular risk factor in uncomplicated arterial hypertension.
Abstract Early detection and management of elevated blood pressure is crucial in reducing the burden of cardiovascular disease (CVD). The importance of an absolute risk assessment and patient risk stratification has been highlighted in the European hypertension guidelines since 2003. Amongst numerous risk factors influencing patient prognosis, elevated heart rate (HR) has been indicated as important predictor of future risk of hypertension, coronary heart disease, sudden cardiac death, heart failure, CVD, stroke, total cancer and mortality. Given that resting HR can be easily determined in clinical practice and mo...
Source: Cardiology Journal - February 25, 2019 Category: Cardiology Authors: Cierpka-Kmieć K, Hering D Tags: Cardiol J Source Type: research

Medication-taking Behaviors and Perceptions Among Adults with Heart Failure (From the REasons for Geographic And Racial Differences in Stroke REGARDS Study)
We examined medication-taking behaviors and perceptions among individuals with HF with a particular focus on BBs. A mailed survey on medication use was administered to US adults with HF enrolled in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Source: The American Journal of Cardiology - February 23, 2019 Category: Cardiology Authors: Matthew T. Mefford, Alysse Sephel, Melissa K. Van Dyke, Ligong Chen, Raegan W. Durant, Todd M. Brown, Matthew Fifolt, Juan Maya, Parag Goyal, Monika M. Safford, Emily B. Levitan Source Type: research

Efficacy and Safety of Ticagrelor Compared with Clopidogrel in Patients with End-Stage Renal Disease with Acute Myocardial Infarction
ConclusionIn patients with ESRD and AMI, ticagrelor resulted in numerically fewer but statistically nonsignificant rates of in-hospital and 1-year cardiovascular events with no significant increase in bleeding events compared with clopidogrel.
Source: American Journal of Cardiovascular Drugs - February 12, 2019 Category: Cardiology Source Type: research

Hypertension in the elderly.
Abstract After 80 years old, antihypertensive treatment significantly reduces cardiovascular events. In the elderly, blood pressure target depends on patients' frailty. After 80 years, French guidelines propose to aim a SBP<150 mmHg without orthostatic hypotension and without exceeding the prescription of more than three antihypertensive drugs. The target may be more ambitious for robust elderly patients. The new 2018 European guidelines set: a stricter target for robust elderly patient aged 80 years or older (SBP between 130 and 139 mmHg and DBP between 70 and 79 mmHg); this objective is less strict for frail ...
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Hernandorena I, Bailly H, Piccoli M, Beunardeau M, Cohen A, Hanon O Tags: Presse Med Source Type: research

Secondary prevention therapies in acute coronary syndrome and relation to outcomes: observational study
Conclusions Use of secondary prevention therapies diminishes over time following an ACS. Patients receiving secondary prevention had decreased rates of death and MACE at 2 years.
Source: Heart Asia - January 12, 2019 Category: Cardiology Authors: Chow, C. K., Brieger, D., Ryan, M., Kangaharan, N., Hyun, K. K., Briffa, T., for the CONCORDANCE Investigators, Brieger, Xu, Kilian, Myers, Parkin, Morrison, Rajaratnam, Tattam, Waites, Baldo, Kamaladasa, Davies, Collins, Nyman, Blenkhorn, Boys, Juergens, Tags: Open access Original research Source Type: research

The role of calcium handling mechanisms in reperfusion injury.
Abstract Cardiovascular diseases, such as stroke and myocardial infarction (MI) remain the major cause of death and disability worldwide. However, the mortality of MI has declined dramatically over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion(percutaneous coronary intervention and cardiopulmonary bypass). Animals studies have been shown that these treatments have been effective in reducing acute myocardial ischemic injury and limiting MI size. The paradox is...
Source: Current Pharmaceutical Design - November 20, 2018 Category: Drugs & Pharmacology Authors: Pittas K, Vrachatis DA, Angelidis C, Tsoucala S, Giannopoulos G, Defteros S Tags: Curr Pharm Des Source Type: research

First-line drugs inhibiting the renin angiotensin system versus other first-line antihypertensive drug classes for hypertension.
CONCLUSIONS: All-cause death is similar for first-line RAS inhibitors and first-line CCBs, thiazides and beta-blockers. There are, however, differences for some morbidity outcomes. First-line thiazides caused less HF and stroke than first-line RAS inhibitors. First-line CCBs increased HF but decreased stroke compared to first-line RAS inhibitors. The magnitude of the increase in HF exceeded the decrease in stroke. Low-quality evidence suggests that first-line RAS inhibitors reduced stroke and total CV events compared to first-line beta-blockers. The small differences in effect on blood pressure between the different classe...
Source: Cochrane Database of Systematic Reviews - November 14, 2018 Category: General Medicine Authors: Chen YJ, Li LJ, Tang WL, Song JY, Qiu R, Li Q, Xue H, Wright JM Tags: Cochrane Database Syst Rev Source Type: research

Systemic blood pressure trends and antihypertensive utilization following continuous-flow left ventricular assist device implantation: an analysis of the interagency registry for mechanically assisted circulatory support.
Conclusions: SBP rises rapidly after CF-LVAD implantation, stabilizing after 3 months, and is matched by concomitant changes in AH utilization; this AH use has increased over consecutive implant years. PMID: 29997951 [PubMed]
Source: Journal of Thoracic Disease - July 14, 2018 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research