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Total 677 results found since Jan 2013.

Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation : A Multinational Population-Based Cohort Study
CONCLUSION: Among patients with AF, apixaban use was associated with lower risk for GIB and similar rates of ischemic stroke or systemic embolism, ICH, and all-cause mortality compared with dabigatran, edoxaban, and rivaroxaban. This finding was consistent for patients aged 80 years or older and those with chronic kidney disease, who are often underrepresented in clinical trials.PRIMARY FUNDING SOURCE: None.PMID:36315950 | DOI:10.7326/M22-0511
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Wallis C Y Lau Carmen Olga Torre Kenneth K C Man Henry Morgan Stewart Sarah Seager Mui Van Zandt Christian Reich Jing Li Jack Brewster Gregory Y H Lip Aroon D Hingorani Li Wei Ian C K Wong Source Type: research

Impact of Smoking on Functional Prognosis after Ischemic Stroke according to Deprivation: A Prospective Cohort Study
Conclusion: The effect of smoking on functional prognosis after ischemic stroke varied according to deprivation status, with poorer outcomes observed in nondeprived patients.Neuroepidemiology
Source: Neuroepidemiology - October 27, 2022 Category: Epidemiology Source Type: research

Days spent at home and mortality after critical illness: a cluster analysis using nationwide data
Chest. 2022 Oct 15:S0012-3692(22)03997-6. doi: 10.1016/j.chest.2022.10.008. Online ahead of print.ABSTRACTBACKGROUND: Beyond the question of short-term survival, days spent at home could be considered a patient-centered outcome in critical care trials.RESEARCH QUESTION: What are the days spent at home and healthcare trajectories during the year after surviving critical illness?STUDY DESIGN AND METHODS: Data were extracted on adult survivors spending at least two nights in a French intensive care unit (ICU) during 2018 who were treated with invasive mechanical ventilation and/or vasopressors or inotropes. Trauma, burn, orga...
Source: Chest - October 18, 2022 Category: Respiratory Medicine Authors: Guillaume L Martin Alice Atramont Marjorie Mazars Ayden Tajahmady Emin Agamaliyev Mervyn Singer Marc Leone Matthieu Legrand Source Type: research

Comparative non-persistence in the first year of treatment with oral anticoagulants in patients with atrial fibrillation: A French comprehensive nationwide study
CONCLUSIONS: In this nationwide observational study, non-persistence rates of oral anticoagulant treatment were high in patients treated for NVAF. Apixaban-treated patients seem to experience lowest discontinuation rates 12 months after treatment initiation compared to patients treated with any other OAC.PMID:36257903 | DOI:10.1016/j.acvd.2022.06.006
Source: Archives of Cardiovascular Diseases - October 18, 2022 Category: Cardiology Authors: Nicolas Danchin Gabriel Steg Isabelle Mah é Olivier Hanon Flore Jacoud Ma ëva Nolin Faustine Dalon Fran çois-Emery Cotte Sabrina Gollety Eric Van Ganse Manon Belhassen Source Type: research

Days spent at home and mortality after critical illness: a cluster analysis using nationwide data
Chest. 2022 Oct 15:S0012-3692(22)03997-6. doi: 10.1016/j.chest.2022.10.008. Online ahead of print.ABSTRACTBACKGROUND: Beyond the question of short-term survival, days spent at home could be considered a patient-centered outcome in critical care trials.RESEARCH QUESTION: What are the days spent at home and healthcare trajectories during the year after surviving critical illness?STUDY DESIGN AND METHODS: Data were extracted on adult survivors spending at least two nights in a French intensive care unit (ICU) during 2018 who were treated with invasive mechanical ventilation and/or vasopressors or inotropes. Trauma, burn, orga...
Source: Chest - October 18, 2022 Category: Respiratory Medicine Authors: Guillaume L Martin Alice Atramont Marjorie Mazars Ayden Tajahmady Emin Agamaliyev Mervyn Singer Marc Leone Matthieu Legrand Source Type: research

Comparative non-persistence in the first year of treatment with oral anticoagulants in patients with atrial fibrillation: A French comprehensive nationwide study
CONCLUSIONS: In this nationwide observational study, non-persistence rates of oral anticoagulant treatment were high in patients treated for NVAF. Apixaban-treated patients seem to experience lowest discontinuation rates 12 months after treatment initiation compared to patients treated with any other OAC.PMID:36257903 | DOI:10.1016/j.acvd.2022.06.006
Source: Archives of Cardiovascular Diseases - October 18, 2022 Category: Cardiology Authors: Nicolas Danchin Gabriel Steg Isabelle Mah é Olivier Hanon Flore Jacoud Ma ëva Nolin Faustine Dalon Fran çois-Emery Cotte Sabrina Gollety Eric Van Ganse Manon Belhassen Source Type: research

Days spent at home and mortality after critical illness: a cluster analysis using nationwide data
Chest. 2022 Oct 15:S0012-3692(22)03997-6. doi: 10.1016/j.chest.2022.10.008. Online ahead of print.ABSTRACTBACKGROUND: Beyond the question of short-term survival, days spent at home could be considered a patient-centered outcome in critical care trials.RESEARCH QUESTION: What are the days spent at home and healthcare trajectories during the year after surviving critical illness?STUDY DESIGN AND METHODS: Data were extracted on adult survivors spending at least two nights in a French intensive care unit (ICU) during 2018 who were treated with invasive mechanical ventilation and/or vasopressors or inotropes. Trauma, burn, orga...
Source: Chest - October 18, 2022 Category: Respiratory Medicine Authors: Guillaume L Martin Alice Atramont Marjorie Mazars Ayden Tajahmady Emin Agamaliyev Mervyn Singer Marc Leone Matthieu Legrand Source Type: research

Patient and aneurysm factors associated with aneurysm recanalization after coiling
Conclusions Several factors are identified by the ARETA study as playing a role in aneurysm recanalization after coiling: current smoking, aneurysm status (ruptured), aneurysm size (≥10 mm), neck size (wide neck), and aneurysm location (middle cerebral artery). This finding has important consequences in clinical practice. Trial registration number URL: http://www.clinicaltrials.gov; Unique Identifier: NCT01942512.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Pierot, L., Barbe, C., Thierry, A., Bala, F., Eugene, F., Cognard, C., Herbreteau, D., Velasco, S., Chabert, E., Desal, H., Aggour, M., Rodriguez-Regent, C., Gallas, S., Sedat, J., Marnat, G., Sourour, N., Consoli, A., Papagiannaki, C., Spelle, L., White, Tags: Open access, Hemorrhagic stroke Source Type: research

Atrial fibrillation detection with long-term continuous Holter ECG recording in patients with high cardiovascular risk and clinical palpitations: the prospective after study
ConclusionsThe systematic AF screening of patients with palpitations and high cardiovascular risk resulted in a diagnostic yield of AF in 14% of the population with a 14-day continuous ECG –Holter monitor. This strategy resulted in the prescription of anticoagulation and antiarrhythmic therapy in 90% of the AF detected population.Graphical abstract
Source: Clinical Research in Cardiology - September 28, 2022 Category: Cardiology Source Type: research

Projected Impact of Treatment Intensification with Satin, Ezetimibe, and Statin plus Ezetimibe Fixed-Dose Combination on MACE Across Six Countries
CONCLUSION: The 2019 ESC/EAS guideline-based treatment intensification with strategies based on statin, ezetimibe, and statin plus ezetimibe FDC is estimated to result in a substantial population-level benefit in terms of MACE averted compared to BAU.PMID:36134461 | DOI:10.1093/eurjpc/zwac214
Source: Atherosclerosis - September 22, 2022 Category: Cardiology Authors: Michel Farnier Raul D Santos Juan Cosin-Sales Marat V Ezhov Jian Liu Denis Granados Serena Santoni Irfan Khan Alberico L Catapano Source Type: research