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Total 31222 results found since Jan 2013.
Comparison of RETREAT and CCFSS Scoring Systems for Risk Estimation of Hepatocellular Carcinoma Recurrence After Radical Resection
CONCLUSION: The RETREAT score demonstrates higher efficacy compared to the CCFSS score in predicting postoperative recurrence in hepatocellular carcinoma (HCC) patients and can serve as a valuable tool for the prognostic evaluation of HCC patients who undergo radical resection. The RETREAT score's superiority can be attributed to its higher area under the curve (AUC) and improved sensitivity and specificity, which allow for better discrimination between positive and negative cases. This enhanced accuracy enables clinicians to make more informed decisions towards post-surgical management and treatment strategies, ultimately...
Source: Alternative Therapies in Health and Medicine - September 7, 2023 Category: Complementary Medicine Authors: Sheng Zhang Xuan Zhang Cong Mo Yunfan Luo Source Type: research
Aflatoxin exposure in adults in southern and eastern Mexico in 2018: A descriptive study
CONCLUSION: AFB1-lys frequency of detection was very high and exposure levels were highest in Veracruz, men, rural areas, and among persons of lower SES. Understanding modifiable HCC risk factors in populations with unique epidemiological patterns could inform preventative interventions.PMID:37672956 | DOI:10.1016/j.ijheh.2023.114249
Source: International Journal of Hygiene and Environmental health - September 6, 2023 Category: Environmental Health Authors: Adriana Monge Mart ín Romero John D Groopman Katherine A McGlynn Luis Santiago-Ruiz Salvador Villalpando-Hern ández Reima Mannan Sean M Burke Jos é María Remes-Troche Mart ín Lajous Source Type: research
Mistakes in managing hepatocellular carcinoma and how to avoid them: a narrative review
Expert Rev Gastroenterol Hepatol. 2023 Sep 7:1-7. doi: 10.1080/17474124.2023.2255515. Online ahead of print.ABSTRACTINTRODUCTION: Hepatocellular carcinoma (HCC) is the most common liver-related cancer and the third leading cause of worldwide cancer-related mortality.AREAS COVERED: There have been many updated guidelines on the management of HCC in the past few years. Given the increasing burden of HCC in clinical practice, knowledge of evidence-based standards of care for these patients is essential for any practitioner managing patients with HCC. Early detection and judicious treatment based on the stage of the HCC can im...
Source: Expert Review of Gastroenterology and Hepatology - September 6, 2023 Category: Gastroenterology Authors: Madunil Anuk Niriella Uditha Dassanayake H Janaka de Silva Source Type: research
Prediction of prognosis of patients with hepatocellular carcinoma based on immune-related score
CONCLUSIONS: Moderate/high-grade immune-related score was significantly associated with better DFS and OS in HCC patients. In addition, a nomogram for prognosis estimation can help clinicians predict the survival status of patients.PMID:37673742 | DOI:10.1016/j.asjsur.2023.08.175
Source: Asian Journal of Surgery - September 6, 2023 Category: Surgery Authors: Xian-Qing Song Rong-Jiang Li Sen Zhang Source Type: research
Comprehensive analysis of P2Y family genes expression, immune characteristics, and prognosis in pan-cancer
CONCLUSION: P2Ys may be used as potential pan-cancer biomarkers in prognosis and immunology. They may also be new targets for tumor immunotherapy, which has wide clinical implications.PMID:37672858 | DOI:10.1016/j.tranon.2023.101776
Source: Translational Oncology - September 6, 2023 Category: Cancer & Oncology Authors: Chuan Liu Xiaoli Wang Siwei Wang Jiankang Xiang Huabing Xie Zongbiao Tan Xinshu Li Jixiang Zhang Weiguo Dong Source Type: research
Sortilin-driven cancer secretome enhances tumorigenic properties of hepatocellular carcinoma via de novo lipogenesis
In conclusion, our study uncovered the role of sortilin in contributing to hepatocarcinogenesis via modulation of the cancer secretome and deregulated lipid metabolism.PMID:37673328 | DOI:10.1016/j.ajpath.2023.08.005
Source: The American Journal of Pathology - September 6, 2023 Category: Pathology Authors: Kristy Kwan-Shuen Chan Kwan-Yung Au Long-Hin Suen Bernice Leung Cheuk-Yan Wong Wei-Qiang Leow Tony Kiat-Hon Lim Irene Oi-Lin Ng Clive Yik-Sham Chung Regina Cheuk-Lam Lo Source Type: research
Prediction of prognosis of patients with hepatocellular carcinoma based on immune-related score
CONCLUSIONS: Moderate/high-grade immune-related score was significantly associated with better DFS and OS in HCC patients. In addition, a nomogram for prognosis estimation can help clinicians predict the survival status of patients.PMID:37673742 | DOI:10.1016/j.asjsur.2023.08.175
Source: Asian Journal of Surgery - September 6, 2023 Category: Surgery Authors: Xian-Qing Song Rong-Jiang Li Sen Zhang Source Type: research
Mistakes in managing hepatocellular carcinoma and how to avoid them: a narrative review
Expert Rev Gastroenterol Hepatol. 2023 Sep 6. doi: 10.1080/17474124.2023.2255515. Online ahead of print.ABSTRACTINTRODUCTION: Hepatocellular carcinoma (HCC) is the most common liver-related cancer and the third leading cause of worldwide cancer-related mortality.AREAS COVERED: There have been many updated guidelines on the management of HCC in the past few years. Given the increasing burden of HCC in clinical practice, knowledge of evidence-based standards of care for these patients is essential for any practitioner managing patients with HCC. Early detection and judicious treatment based on the stage of the HCC can improv...
Source: Expert Review of Gastroenterology and Hepatology - September 6, 2023 Category: Gastroenterology Authors: Madunil Anuk Niriella Uditha Dassanayake H Janaka de Silva Source Type: research
Aflatoxin exposure in adults in southern and eastern Mexico in 2018: A descriptive study
CONCLUSION: AFB1-lys frequency of detection was very high and exposure levels were highest in Veracruz, men, rural areas, and among persons of lower SES. Understanding modifiable HCC risk factors in populations with unique epidemiological patterns could inform preventative interventions.PMID:37672956 | DOI:10.1016/j.ijheh.2023.114249
Source: International Journal of Hygiene and Environmental health - September 6, 2023 Category: Environmental Health Authors: Adriana Monge Mart ín Romero John D Groopman Katherine A McGlynn Luis Santiago-Ruiz Salvador Villalpando-Hern ández Reima Mannan Sean M Burke Jos é María Remes-Troche Mart ín Lajous Source Type: research
Comprehensive analysis of P2Y family genes expression, immune characteristics, and prognosis in pan-cancer
CONCLUSION: P2Ys may be used as potential pan-cancer biomarkers in prognosis and immunology. They may also be new targets for tumor immunotherapy, which has wide clinical implications.PMID:37672858 | DOI:10.1016/j.tranon.2023.101776
Source: Translational Oncology - September 6, 2023 Category: Cancer & Oncology Authors: Chuan Liu Xiaoli Wang Siwei Wang Jiankang Xiang Huabing Xie Zongbiao Tan Xinshu Li Jixiang Zhang Weiguo Dong Source Type: research
Mistakes in managing hepatocellular carcinoma and how to avoid them: a narrative review
Expert Rev Gastroenterol Hepatol. 2023 Sep 7:1-7. doi: 10.1080/17474124.2023.2255515. Online ahead of print.ABSTRACTINTRODUCTION: Hepatocellular carcinoma (HCC) is the most common liver-related cancer and the third leading cause of worldwide cancer-related mortality.AREAS COVERED: There have been many updated guidelines on the management of HCC in the past few years. Given the increasing burden of HCC in clinical practice, knowledge of evidence-based standards of care for these patients is essential for any practitioner managing patients with HCC. Early detection and judicious treatment based on the stage of the HCC can im...
Source: Expert Review of Gastroenterology and Hepatology - September 6, 2023 Category: Gastroenterology Authors: Madunil Anuk Niriella Uditha Dassanayake H Janaka de Silva Source Type: research
Sortilin-driven cancer secretome enhances tumorigenic properties of hepatocellular carcinoma via de novo lipogenesis
In conclusion, our study uncovered the role of sortilin in contributing to hepatocarcinogenesis via modulation of the cancer secretome and deregulated lipid metabolism.PMID:37673328 | DOI:10.1016/j.ajpath.2023.08.005
Source: Am J Pathol - September 6, 2023 Category: Pathology Authors: Kristy Kwan-Shuen Chan Kwan-Yung Au Long-Hin Suen Bernice Leung Cheuk-Yan Wong Wei-Qiang Leow Tony Kiat-Hon Lim Irene Oi-Lin Ng Clive Yik-Sham Chung Regina Cheuk-Lam Lo Source Type: research
