Sortilin-driven cancer secretome enhances tumorigenic properties of hepatocellular carcinoma via de novo lipogenesis

In conclusion, our study uncovered the role of sortilin in contributing to hepatocarcinogenesis via modulation of the cancer secretome and deregulated lipid metabolism.PMID:37673328 | DOI:10.1016/j.ajpath.2023.08.005

Source: The American Journal of Pathology - September 6, 2023 Category: Pathology Authors: Kristy Kwan-Shuen Chan Kwan-Yung Au Long-Hin Suen Bernice Leung Cheuk-Yan Wong Wei-Qiang Leow Tony Kiat-Hon Lim Irene Oi-Lin Ng Clive Yik-Sham Chung Regina Cheuk-Lam Lo Source Type: research