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Cancer: Endometrial Cancer
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Total 190 results found since Jan 2013.
Role of miR-139-5p in ectopic endometrial stromal cells and the underlying molecular mechanism
In conclusion, the results of the present study suggested that miR-139-5p may play a key role in the progression of endometriosis by regulating the viability of ESCs and directly targeting BBC3.PMID:34539847 | PMC:PMC8438670 | DOI:10.3892/etm.2021.10686
Source: Experimental and Therapeutic Medicine - September 20, 2021 Category: General Medicine Authors: Lixia Feng Xu Chen Shenghua Zhang Yunxia Chen Yanling Yu Source Type: research
Knockdown of YKL-40 inhibits angiogenesis through regulation of VEGF/VEGFR2 and ERK1/2 signaling in endometrial cancer
This article is protected by copyright. All rights reserved.PMID:34498339 | DOI:10.1002/cbin.11699
Source: Cell Biology International - September 9, 2021 Category: Cytology Authors: Hong-Yan Chen Zhao-Yu Zhou Yan-Lu Luo Qin Luo Jiang-Tao Fan Source Type: research
GSE174741 LINC01133 inhibits invasion and promotes proliferation in an endometriosis epithelial cell line
Contributors : Quanah J Hudson ; Iveta Yotova ; Florian M Pauler ; Rene WenzlSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEndometriosis is a common gynecological disorder characterized by ectopic growth of endometrium outside the uterus and associated with chronic pain and infertility. We investigated the role of LINC01133 in endometriosis, an lncRNA that has been implicated in several types of cancer. We found that LINC01133 is upregulated in ectopic endometriosis lesions. As expression appeared higher in the epithelial endometrial layer, we performed an siRNA knockdown of LINC011...
Source: GEO: Gene Expression Omnibus - August 23, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Transcriptomic analysis of hormone-sensitive patient-derived endometrial cancer spheroid culture defines Efp as a proliferation modulator
This study provides an insight into alternative EC therapeutic strategies targeting ERα-Efp axis.PMID:33647797 | DOI:10.1016/j.bbrc.2021.02.066
Source: Biochemical and Biophysical Research communications - March 1, 2021 Category: Biochemistry Authors: Chiujung Yang Kazuhiro Ikeda Kuniko Horie-Inoue Wataru Sato Kosei Hasegawa Satoru Takeda Atsuo Itakura Satoshi Inoue Source Type: research
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells
ConclusionUCA1 is highly expressed in EMS and promotes the proliferation of ESCs but suppresses autophagy and apoptosis. In EMS, UCA1 may be a prognostic marker and therapeutic target.
Source: Frontiers in Oncology - February 18, 2021 Category: Cancer & Oncology Source Type: research
WTAP facilitates progression of endometrial cancer via CAV-1/NF- κB axis.
This article is protected by copyright. All rights reserved.
PMID: 33559954 [PubMed - as supplied by publisher]
Source: Cell Biology International - February 9, 2021 Category: Cytology Authors: Li Q, Wang C, Dong W, Su Y, Ma Z Tags: Cell Biol Int Source Type: research
Downregulation of HOXA11 enhances endometrial cancer malignancy and cisplatin resistance via activating PTEN/AKT signaling pathway
ConclusionLow HOXA11 expression may promote the proliferation, migration, invasion of endometrial cancer cells, and increase their resistance to cisplatin through activating PTEN/AKT pathway.
Source: Clinical and Translational Oncology - January 30, 2021 Category: Cancer & Oncology Source Type: research
Impact of mitochondrial transcription factor A expression on the outcomes of ovarian, endometrial and cervical cancers.
Authors: Hu W, Ma SL, Liu LL, Zhu YH, Zeng TT, Li Y, Guan XY
Abstract
Gynecologic cancers, including endometrial, ovarian, and cervical cancers, are the leading causes of cancer-related mortality in women worldwide. Mitochondrial transcription factor A (TFAM) has been demonstrated playing critical roles in the development of tumors. However, the clinical relationship of TFAM expression in gynecologic cancers requires further clarification. Our results showed gynecologic cancer cells are highly expressed TFAM in both protein and RNA levels compared to normal cells. The TCGA dataset revealed that TFAM gene expression...
Source: American Journal of Translational Research - October 13, 2020 Category: Research Tags: Am J Transl Res Source Type: research
