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Cancer: Thyroid Cancer

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Effects of RNA interference of CTHRC1 on proliferation and apoptosis of thyroid papillary cancer TCP-1 cells < em > in vitro < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Apr 20;41(4):549-554. doi: 10.12122/j.issn.1673-4254.2021.04.10.ABSTRACTOBJECTIVE: To explore the role of CTHRC1 in regulating the proliferation and apoptosis of papillary thyroid cancer cells.OBJECTIVE: Papillary thyroid cancer TPC-1 cells were transfected with a small interfering RNA (siRNA) targeting CTHRC1, with the cells transfected with a scrambled sequence as the negative control. The changes in cell proliferation and apoptosis were assessed using cell counting kit-8 (CCK-8) and flow cytometry with AV/PI double staining, respectively. The expression of c-caspase-3, c-PARP1 and pho...
Source: Journal of Southern Medical University - May 8, 2021 Category: Universities & Medical Training Authors: Z Tang X Ding S Qin C Zhang Source Type: research