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Drug: Nicotine

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Total 8587 results found since Jan 2013.

Examining the Relationship Between Past Orientation and US Suicide Rates: An Analysis Using Big Data-Driven Google Search Queries
Conclusions: We empirically identified the positive relationship between the suicide rate and past orientation, which was measured by big data-driven Google search query.
Source: Journal of Medical Internet Research - February 11, 2016 Category: Journals (General) Authors: Donghyun LeeHojun LeeMunkee Choi Source Type: research

Influence of legislations and news on Indian internet search query patterns of e-cigarettes
Conclusions: These findings suggest that search for information on ENDS is increasing and that these tobacco control policies and news items, targeting tobacco usage reduction, have only a short-term effect on the rate of searching for information on ENDS.
Source: Journal of Oral and Maxillofacial Pathology - August 18, 2017 Category: ENT & OMF Authors: Rooban Thavarajah Anusa Arunachalam Mohandoss Kannan Ranganathan Srinivas Kondalsamy-Chennakesavan Source Type: research

Why do adult dogs (Canis familiaris) commit the A-not-B search error?
It has been recently reported that adult domestic dogs, like human infants, tend to commit perseverative search errors; that is, they select the previously rewarded empty location in Piagetian A-not-B search task because of the experimenter’s ostensive communicative cues. There is, however, an ongoing debate over whether these findings reveal that dogs can use the human ostensive referential communication as a source of information or the phenomenon can be accounted for by “more simple” explanations like insufficient attention and learning based on local enhancement. In 2 experiments the authors systematically manipu...
Source: Journal of Comparative Psychology - August 19, 2013 Category: Psychiatry & Psychology Authors: Sümegi, Zsófia; Kis, Anna; Miklósi, Ádám; Topál, József Source Type: research

Identifying e-cigarette vape stores: description of an online search methodology
Conclusions Using the online search methodology we identified more ENDS vape stores than were on the state tobacco licensure list. This approach may be a promising strategy to identify and track the growth of ENDS vape stores over time, especially in states without a systematic licensing requirement for such stores.
Source: Tobacco Control - March 30, 2016 Category: Respiratory Medicine Authors: Kim, A. E., Loomis, B., Rhodes, B., Eggers, M. E., Liedtke, C., Porter, L. Tags: Articles Source Type: research

Nicotine promotes the utility of short-term memory during visual search in macaque monkeys
ConclusionsNicotine improves visual search, mainly by increasing the utility of short-term memory, with minimal changes in oculomotor parameters.
Source: Psychopharmacology - July 8, 2022 Category: Psychiatry Source Type: research

Revisiting the Rise of Electronic Nicotine Delivery Systems Using Search Query Surveillance
Conclusions ENDS popularity is rapidly growing and evolving. These findings could inform survey questionnaire development for follow-up investigation and immediately guide policy debates about how the public perceives the health risks or cessation benefits of ENDS.
Source: American Journal of Preventive Medicine - February 14, 2016 Category: Global & Universal Source Type: research

Examining the relationship between past orientation and US suicide rates: an analysis using big data-driven Google search queries - Lee D, Lee H, Choi M.
BACKGROUND: Internet search query data reflect the attitudes of the users, using which we can measure the past orientation (Zimbardo Time Perspective Inventory) to commit suicide. Examinations of past orientation often highlight certain predispositions of ...
Source: SafetyLit - February 27, 2016 Category: Global & Universal Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

'Real Life Bridget Jones' Shares An Update In Her Long Search For Love
When "Bridget Jones' Diary" came to the big screen in 2001, New York singleton Kim Coykendall related to the title character's messy, seemingly hopeless search for love -- in a big way. Kim's own relationship woes were what movies were made of, she said. The 34-year-old teacher dubbed herself a "real-life Bridget Jones" and shared her Bridget-Jones-level lows with the world on a 2004 episode of "The Oprah Winfrey Show." First, Kim's "back-up man" fell through. "We had a pact that when we were 30 years old, if we were still single, we would get married," Kim said. "Well, I introduced him to one of my friends and now they'r...
Source: Healthy Living - The Huffington Post - May 4, 2016 Category: Consumer Health News Source Type: news

Academic job search
I'm currently in the process of job search/application for an academic position. As you can imagine, the timelines at different institutions are slightly different, so while I've finished interviews at some places, I'm just starting them at other places. I've received term sheets (supposedly non-binding) for some institutions, and there's a deadline for me to sign them. I'm not quite sure if I want to 100% commit to these places yet since I still have a few more interviews going on. So, it... Read more
Source: Student Doctor Network - September 27, 2021 Category: Universities & Medical Training Authors: Yui Tags: Hematology / Oncology Source Type: forums

SOCS3 participates in cholinergic pathway regulation of synovitis in rheumatoid arthritis.
This study investigated the effect of SOCS on cholinergic pathway regulation of synovitis in the fibroblast-like synoviocytes (FLSs) of RA and CIA mice. The effects of nicotine on SOCS1 and SOCS3 protein expression in FLSs were assayed by western blotting before and after transfection with a small interfering RNA oligonucleotide (SOCS3-siRNA or control-siRNA). Interleukin-6 was measured by enzyme-linked immunosorbent assay of SOCS3-siRNA and control-siRNA transfected FLS culture supernatants. Histopathological evaluation and immunohistochemical staining of SOCS3 were performed in joint tissue sections of control, CIA model...
Source: Connective Tissue Research - September 17, 2017 Category: Research Tags: Connect Tissue Res Source Type: research

Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts.
Abstract Cigarette smoke is the major cause of chronic obstructive pulmonary disease (COPD), yet pathogenic mechanisms are not fully understood. Vascular endothelial growth factor (VEGF) is one of the major regulators of endothelial cell survival and is believed to play a role in the pathogenesis of COPD. Fibroblasts are a significant source of VEGF in the lungs; however the effect of cigarette smoke exposure on VEGF release by fibroblasts is not fully understood. We hypothesized that cigarette smoke-induced disturbed VEGF release by human lung fibroblasts is a potential pathogenic mechanism that could contribute ...
Source: Toxicology Letters - April 22, 2013 Category: Toxicology Authors: Farid M, Kanaji N, Nakanishi M, Gunji Y, Michalski J, Iwasawa S, Ikari J, Wang X, Basma H, Nelson AJ, Liu X, Rennard SI Tags: Toxicol Lett Source Type: research

Sinomenine increases adenosine A < sub > 2A < /sub > receptor and inhibits NF- κB to inhibit arthritis in adjuvant-induced-arthritis rats and fibroblast-like synoviocytes through α7nAChR
J Leukoc Biol. 2021 Aug 23. doi: 10.1002/JLB.3MA0121-024RRRR. Online ahead of print.ABSTRACTSinomenine (SIN) is a clinical drug for treating rheumatoid arthritis (RA) in China. Our previous study found SIN inhibited inflammation via alpha7 nicotinic acetylcholine receptor (α7nAChR) in macrophages in vitro. Adenosine receptor A2A has anti-inflammatory and immunosuppressive function. However, the mechanisms of SIN acting on α7nAChR and the effect on adenosine A2A receptor (A2A R) in RA are not clear. In the present study, the effects of SIN on adjuvant-induced-arthritis (AIA) rats in vivo and on fibroblast-like synoviocyte...
Source: Journal of Leukocyte Biology - August 23, 2021 Category: Hematology Authors: Lang Yi Junyu Ke Jiayan Liu Huili Lai Yanjun Lv Chong Peng Yingkun Zhi Qun Du Liang Liu Peixun Wang Hua Zhou Yan Dong Source Type: research

Nicotine Induced Epithelial-Mesenchymal Transition via Wnt/β-catenin Signaling in Human Airway Epithelial Cells.
Conclusion: These results suggest that HBECs are able to undergo EMT in vitro upon nicotine stimulation via the Wnt3a/β-catenin signaling pathway. PMID: 23204070 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - November 30, 2012 Category: Cytology Authors: Zou W, Zou Y, Zhao Z, Li B, Ran P Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research