Cancer stem cells: A comprehensive review on identification and therapeutic implications
BR Varun, P Jayanthi, Pratibha RamaniJournal of Oral and Maxillofacial Pathology 2020 24(1):190-190 Cancer stem cells (CSCs) are distinct subpopulations of tumor cells that possess the ability for perpetual self-renewal and proliferation. They produce downstream progenitor cells and cancer cells that drive tumor growth. Studies of many cancer types including oral squamous cell carcinoma (OSCC) have identified CSCs using specific markers, but it is still unclear as to where in the stem cell hierarchy these markers fall. This is compounded further by the presence of multiple CSC subtypes within OSCC, making investigation re...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: BR Varun P Jayanthi Pratibha Ramani Source Type: research

Epithelial & #8211;mesenchymal transition in oral squamous cell carcinoma: An insight into molecular mechanisms and clinical implications
P Jayanthi, BR Varun, J SelvarajJournal of Oral and Maxillofacial Pathology 2020 24(1):189-189 Epithelial–mesenchymal transition (EMT) is an important event in embryonic development, fibrosis and cancer invasion. During cancer progression, the activation of EMT permits cancer cells to acquire migratory, invasive and stem-like properties. Despite recent advances in treatment, there is no improvement in the 5-year overall survival rate of oral squamous cell carcinoma (OSCC). Local recurrence and lymph node metastasis are considered to be mainly responsible for the low survival rate in OSCC. EMT plays a major role in l...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: P Jayanthi BR Varun J Selvaraj Source Type: research

Malignant potentiality assessment of oral submucous fibrosis through semi-quantitative approach
Conclusion: This newly proposed diagnostic cum prognostic decision-making parameter, the “MPI” may bring a value addition to the conventional diagnostic gold standard. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Mousumi Pal Debaleena Nawn Pooja Lahiri Debnath Das Ranjan Rashmi Paul Debjani Chakraborty Source Type: research

Punica granatum as a salutiferous superfruit in the treatment of oral candidiasis & #8211; An in-vitro study
Conclusions: The results of this study indicate that P. granatum peel extract can be used as an effective natural substitute for synthetic antifungal agents. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: KS Prem Kumar S Shiny Samlin B Siva R Sudharshan A Vignesswary K Divya Source Type: research

Salivary glucose levels in diabetes mellitus patients: A case & #8211;control study
Conclusion: Salivary glucose level estimation can be used as a potential indicator in screening, diagnosis and monitoring of diabetes mellitus. Furthermore, it is an easy and noninvasive method. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Vineet Gupta Amanpreet Kaur Source Type: research

Microwave-assisted tissue processing, fixation and staining in tissues of different thicknesses: A comparative study
Conclusion: The ease of application and speed of this technique significantly reduced turnaround time in diagnostic labs. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Mahesh Rao Shaila M Pai Sanjeev Balappa Khanagar Salman Siddeeqh Darshan Divakar Devang Sachin Naik Source Type: research

Galectin-1 expression in oral squamous cell carcinoma: An immunohistochemical study
Conclusion: Gal-1 plays an important role in invasion, metastasis and as a prognostic marker. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Vaibhavi Salunkhe Aarti Mahajan Nilima Prakash GL Pradeep Rekha Patil Sajda Khan Gajdhar Source Type: research

Odontogenic tumors: A review of 93 cases in the Vidharba region of Maharashtra
Conclusion: OTs were found to be rare in the sample studied. The findings of the study were in concordance to those of Asian and African series. Variations were shown from the series of American reports, and further investigations are needed for this disparity. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Preethi Narendra Sharma Rajul Kamalkishore Ranka Minal Shashi Chaudhary Madhuri Nitin Gaw Alka Harish Hande Prajakta Fande Zade Source Type: research

Immunoexpression of p53 in histologically negative surgical margins adjacent to oral squamous cell carcinoma:A preliminary study
Mamata S Kamat, Bhagwan Das Rai, Rudrayya S Puranik, Uma V DatarJournal of Oral and Maxillofacial Pathology 2020 24(1):184-184 The prognostic significance of genetic changes occurring in the histologically negative surgical margins (HNMs) has been focus of various studies recently. Since p53 is the most frequently observed genetic alteration found in oral squamous cell carcinoma (OSCC), we hypothesized that a similar variation might be evident in HNMs as well. Literature is scarce regarding comparison of expression of p53 in the tumor tissue and its adjacent HNMs; hence, the aim of the present study was to study p53 immun...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Mamata S Kamat Bhagwan Das Rai Rudrayya S Puranik Uma V Datar Source Type: research

Odontogenic keratocyst: Analysis of recurrence by AgNOR, p53 and MDM2 profiling
Conclusion: There was a significant difference in the staining pattern of MDM2 and AgNOR in the recurrent group as compared to the nonrecurrent group. The higher expression of these markers in recurrent lesions may be important in order to consider additional surgical interventions to improve prognosis. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Chetana Chandrashekar Pratik Patel Aatish Thennavan Raghu Radhakrishnan Source Type: research

Assessment of lactate dehydrogenase enzyme levels in saliva and serum of oral submucous fibrosis and leukoplakia patients
Conclusion: A significant difference was found between mean salivary LDH Levels and serum LDH levels in patients with leukoplakia, OSMF and health controls. A positive correlation was also established between salivary and serum LDH levels in patients with OSMF and leukoplakia patients making saliva a potent non invasive tool for early prediction and detection of PMOD and its malignant transformation. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Abikshyeet Panda Shyam Sundar Behura Lipsa Bhuyan Kailash Chandra Dash Vijay Kumar Shirsha Mukherjee Source Type: research

Compact osteoma of the maxilla: A rare case report
Umesh Yadalam, Partha Pratim Roy, Aditi Bose, T SmithaJournal of Oral and Maxillofacial Pathology 2020 24(1):179-182 Osteomas of the facial bones are a rare entity and very few cases have been reported in the literature.Osteoma is a benign osteogenic lesion with a very slow growth, characterized by proliferation of either cancellous or compact bone. This paper describes a case of a 27 year old male seeking treatment for a slowly enlarging lesion in the maxillary right anterior region. Surgical excision of the lesion was done and the histopathologic evaluation revealed dense compact bone with osteocytes in the lacunae sugg...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Umesh Yadalam Partha Pratim Roy Aditi Bose T Smitha Source Type: research

Ten-cusped primary molar tooth: A rare entity with literature review
EJ Akhil Jose, Plato Palathingal, Mebin George Mathew, Md Muzammil KhanJournal of Oral and Maxillofacial Pathology 2020 24(1):176-178 Teeth arise by complex and progressive interactions between the ectoderm, oral epithelium and underlying mesenchyme. However, it may show variations and changes in morphological structure. A 6-year-old female child patient came for the treatment of her carious tooth. Intraoral examination revealed supernumerary cusp on occlusal surface of the maxillary right second primary molar. Incidence of supernumerary cusp is a rare condition formed by abnormal proliferation and folding of inner enamel...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: EJ Akhil Jose Plato Palathingal Mebin George Mathew Md Muzammil Khan Source Type: research

Strawberry gingivitis & #8211; First sign of Wegener & #39;s granulomatosis
Chandulal D Dhalkari, Sayali Chandrakant Patil, Maya S IndurkarJournal of Oral and Maxillofacial Pathology 2020 24(1):172-175 Wegener's Granulomatosis (WG) is an immunologically mediated rare multisystem disease characterized by necrotizing granulomatous inflammation affecting the upper and lower respiratory tracts, disseminated vasculitis and glomerulonephritis. WG oral lesions are reported to occur in 6%–13% of patients; they were an initial presenting feature in only 2% of cases. A case of strawberry gingivitis as the first sign of WG presented with erythematous and painful localized gingival enla...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Chandulal D Dhalkari Sayali Chandrakant Patil Maya S Indurkar Source Type: research

Bisphosphonate-related spindle cell carcinoma and osteonecrosis
Nazanin Mahdavi, Kheirandish Yasaman, A Garajei, Naeimeh Nikfarjam NouriJournal of Oral and Maxillofacial Pathology 2020 24(1):168-171 A 48-year-old female with a complaint of persistent pain referred to the Imam Khomeini (Tehran, Iran) in 2018. Based on the radiographic findings, radiolucent lesion found in the right mandible and she had alendronate administration approximately for 10 years. Since the past 6 months, the lesion detected in the right mandible. According to the computed tomography scan, a large lytic destructive lesion with a soft-tissue component was seen at the right mandibular ramus. Microscopic examinat...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Nazanin Mahdavi Kheirandish Yasaman A Garajei Naeimeh Nikfarjam Nouri Source Type: research

Schwannoma of head-and-neck region: A clinical chameleon & #8211; Report of two cases occurring at rare sites with unusual clinical manifestations
We report two cases of schwannomas, one in the nasal cavity and the other in the tongue, that were considered to be an infective lesion and malignant lesion respectively on clinical evaluation. The biopsy and subsequent histopathological examination led to the diagnosis of schwannoma. It is important to be aware of the unusual clinical manifestations of schwannomas and keep it in the differential diagnoses, even at relatively uncommon sites such as the nasal and oral cavities. Lesions that are suspected to be infectious lesions or malignant lesions on clinical and/or radiological evaluation can also be schwannomas. Unneces...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Mayank Kumar Meenakshi Rao Poonam Elhence Darwin Kaushal Taruna Yadav Source Type: research

Odontogenic sarcoma: First report after new who nomenclature with systematic review
The objective of this study is to systematically review the studies that reported AFS arising de novo and AFS arising from AF. Articles that reported AFS arising de novo and AFS arising from AF were collected from PubMed, Medline, Embase, Cochrane, Google search and manual search. The results of the systematic review showed that six studies (46.1%) reported AFS arised de novo with no previous history of AF. Seven studies (53.84%) reported that amelobastic fibrosarcoma arised from AF. A rare case of odontogenic sarcoma transformed from AF is reported here. This is the first case report to be published on odontogenic...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Pratibha Ramani Reshma Poothakulath Krishnan Monika Karunagaran MR Muthusekhar Source Type: research

Role of artificial intelligence in diagnostic oral pathology-A modern approach
This study presented an overview of AI, its recent advances in pathology and future prospects. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Ayinampudi Bhargavi Krishna Azra Tanveer Pancha Venkat Bhagirath Ashalata Gannepalli Source Type: research

Pink bodies with halo
We present three case reports where the oral biopsy was taken from the gingival region of a 30-year-old female, a 32-year-old male patient and another from the buccal mucosa of a 67-year-old male patient. Histopathologically, the three cases were finally diagnosed as pyogenic granuloma and moderately differentiated squamous cell carcinoma with the presence of clusters of Toto bodies in the upper spinous layer of stratified squamous epithelium. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Sushruth Nayak Asha Karadwal Amit Aggarwal Prachi Nayak Source Type: research

Expression of metallothionein in oral squamous cell carcinoma: A systematic review
Palati Sinduja, Pratibha Ramani, S Gheena, Abilasha RamasubramanianJournal of Oral and Maxillofacial Pathology 2020 24(1):143-147 Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule making them highly reactive species. The free radicals are also known to play a dual role in biological systems, as they can be either beneficial or harmful. It has been proven that there are numerous mechanisms participating in the protection of a cell against free radicals. In this systematic review, we have reviewed metallothioneins (MTs) which are a small, cysteinerich and heavy...
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Palati Sinduja Pratibha Ramani S Gheena Abilasha Ramasubramanian Source Type: research

Malocclusion: An adjunctive aid in individual identification
Conclusion: Orthodontists prepare various antemortem records for diagnostic purposes, i.e., photographs, the impression of the teeth and palate, lateral cephalograms, orthopantomograms and hand-wrist radiographs. If orthodontists recorded additional data of finger and lip prints, the archives of an orthodontist would be of tremendous profit to forensic sciences in individual identification. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: N Goutham RJ Shishira AM Shailaja HK Vedavathi KS Sowmya S Neeharika Source Type: research

Quantitative analysis of tumor-associated tissue eosinophils and tumor-associated blood eosinophils in oral squamous cell carcinoma
Conclusion: There was a statistically significant correlation between TATE and histological grades of OSCC. Eosinophilia of the peripheral blood is an adverse sign in patients with carcinoma. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Safia Siddiqui Rohit Jaiswal Ghulam Sarwar Hashmi Source Type: research

Immunohistochemical detection of Tyrosine Kinase receptor (TrK) in follicular and plexiform ameloblastoma & #8211; A novel study
Conclusion: The expression pattern of TrK is found to be more in plexiform ameloblastoma than follicular ameloblastoma. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: George Babu Jisha Vadivel Ilayaraja Thuckanickenpalayam Ragunathan Yoithapprabhunath Nalliappan Ganapathy Janardhanam Dineshshankar Ramadas Madhavan Nirmal Source Type: research

Oral microbial profile in oral cancer patients before and after radiation therapy in a cancer care center & #8211;A prospective study
Conclusion: High prevalence of Streptococcus sp. was found in patients of oral cancer before radiotherapy, while Candida albicans and Klebsiella species and Pediococcus species are the significant pathogens isolated in postradiotherapy cancer patients. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: K Anjali AB Arun TS Bastian R Parthiban M Selvamani H Adarsh Source Type: research

Evaluation for noncompliance of recall in patients reporting to oral pathology department: Longitudinal study of 5 years
Conclusion: This study highlights patient recall appointment noncompliance, ascribing various reasons to the patient's attrition rate for recall appointments. Probable solutions for increasing the compliance for recall need to be addressed, and further research should be conducted to evaluate these solutions. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Anuradha Sinha Shivani Bansal Pankaj M Shirsat Pooja Prasad Rajiv S Desai Source Type: research

Qualitative expression of hypoxia-inducible factor-1 & #945; in malignant transformation of oral submucous fibrosis: An immunohistochemical study
Conclusion: HIF-1α appears to play a role in malignant transformation of OSF. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Treville Pereira Ridima Surve Subraj Shetty Swati Gotmare Source Type: research

New diagnostic markers in basal cell carcinoma
Conclusion: It seems that changes in lipid profile can help as a diagnostic marker for detecting cancer like BCC. Although this change could be different in lipid markers and also among different types of cancer. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Sadaf Anghaei Kambiz Kamyab-Hesari Shahriar Haddadi Maryam Jolehar Source Type: research

Effect of Ocimum sanctum extract on leukemic cell lines:A preliminary in-vitro study
Conclusion: This being preliminary study, we propose the initial finding of cytotoxic abilities of the herb against the leukemic cell lines and recommend a more detailed evaluation of the herb and its components. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: M Harsha KP Mohan Kumar Santosh Kagathur Vikram S Amberkar Source Type: research

Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study
Conclusion: The data attained from this study highlight the need for community-based screening and awareness programs for general population and thus obtain a healthier society. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Shruti Singh Jaya Singh Shaleen Chandra Fahad Mansoor Samadi Source Type: research

Comparative evaluation of staining efficacy of calcofluor white and acridine orange for detection of Candida species using fluorescence microscopy & #8211; A prospective microbiological study
Conclusions: CFW is a better fluorescent stain when compared to AO to detect Candida species in tissue sections of OSCC cases. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Vishal Punjabi Shilpa Patel Jigna Pathak Niharika Swain Source Type: research

Relative frequency of oral focal reactive overgrowths: An institutional retrospective study
Conclusions: Nevertheless, information of the frequency and distribution of these lesions is favorable when establishing a diagnosis and treatment plan in clinical practice. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Bhagirathi D Lakkam Madhusudan Astekar Shakir Alam Gaurav Sapra Ashutosh Agarwal Aditi Murari Agarwal Source Type: research

Isolation, culture and characterization of primary cell lines of human buccal mucosal fibroblasts: A combination of explant enzamytic technique
Conclusion: Using the combination technique, we were successful in isolating the cells at a faster rate by detachment of cells on day 3 and confluency on day 10. The morphological assessment and STR profiling further confirmed that the isolated cell lines resemble human fibroblast cells. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Ritiha Patil Alka D Kale Deepa R Mane Dhanashree Patil Source Type: research

Can coffee combat caries ? An in vitro study
Conclusion: Our study proved that coffee has anticariogenic activity against S. mutans. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Divyasri Godavarthy Rashmi Naik Praveen Kumar Gali BR Ahmed Mujib Venkata Ramana Reddy Baddam Source Type: research

Characterization of perineural invasion in different histological grades and variants of oral squamous cell carcinoma
Conclusion: The present study showed that there is a direct proportionality between PNI and different grades and stages of OSCC. Given this context, a histopathologist ought to examine for PNI and make it mandatory to report the same to the clinician for better treatment and follow-up of the patient. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: G Deepthi N D V N Shyam G Kiran Kumar Vaishali Narayen K Paremala P Preethi Source Type: research

Establishing the accuracy of a new and cheaper sample collection tool: Oral cytology versus oral histopathology
Conclusion: Our study proves that the use of wooden end of a sterile cotton swab stick offers a low cost and fairly effective solution which is not only easily available but can be potentially applied as a mass screening tool at primary health-care centers. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Anubhuti Sood Deepika Mishra Rahul Yadav Krushna Bhatt Harsh Priya Harpreet Kaur Source Type: research

Serum C-reactive protein in oral submucous fibrosis and oral squamous cell carcinoma: A cross-sectional study
Conclusions: Serum CRP levels in patients with OSMF were raised, but not statistically significant as compared to the control group. Values of serum CRP were significantly higher in patients with OSCC as compared to the control group, and it was statistically significant; these values also showed positive association with primary tumor size. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Suchitra Rajesh Gosavi Amruta Appasaheb Torkadi Source Type: research

Syringic acid induces apoptosis in human oral squamous carcinoma cells through mitochondrial pathway
Conclusion: SA specifically induces cell death and inhibits the proliferation in OSCC cells through intrinsic/mitochondrial apoptosis pathway, suggesting that SA may be an effective agent for the treatment of human OSCC. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Bhaskhar Abijeth Devaraj Ezhilarasan Source Type: research

Study of Hypoxia-inducible factor-2 & #945; expression in the malignant transformation of Oral submucous fibrosis
Conclusion: Areca nut initiates fibrosis and subsequent hypoxia in OSF which triggers HIF-2α expression in the epithelium. HIF-2α could be a surrogate marker for cancer initiation and progression. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Immanuel Joseph Joshua Elizabeth Umadevi K Rao Kannan Ranganathan Source Type: research

Clinicomicrobiological evaluation of the efficacy of local delivery of moxifloxacin and ibuprofen gel as an adjunct to scaling and root planing in chronic periodontitis patients
Conclusions: Among the two treatment modalities, treatment with moxifloxacin and ibuprofen local delivery as an adjunct to SRP gave superior results in clinical and microbiological parameters compared to SRP group. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Ramyasri Kadadasu Abhinav Atchuta Rajababu Palaparthy S Harinath Reddy Vidyasagar Sisinty Mounika Beeravolu Source Type: research

Elucidating the role of excision repair cross-complement group 1 in oral epithelial dysplasia and early invasive squamous cell carcinoma: An immunohistochemical study
Conclusion: Disruption in the mechanisms that regulate cell cycle checkpoints and DNA repair mechanism results in genomic instability; these alterations might contribute to carcinoma. ERCC1 is essential to repair the DNA damage induced by various carcinogens. The present study shows significant difference in the expression of ERCC1 between EISCC and OED, which suggests ERCC1 could be used as one of the predictive markers. (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Spoorti Kulkarni Monica Solomon Deepthi Pankaj Sunitha Carnelio Chetana Chandrashekar Nisha Shetty Source Type: research

The enigma of signet ring cells
Gitika Sharma, Mala KambojJournal of Oral and Maxillofacial Pathology 2020 24(1):18-19 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Gitika Sharma Mala Kamboj Source Type: research

Can B- cell based immunotherapy be our new perspective to exit cancer ?
Anela Thomas, T SmithaJournal of Oral and Maxillofacial Pathology 2020 24(1):15-17 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Anela Thomas T Smitha Source Type: research

Dr. R. M. Mathur
Shaleen ChandraJournal of Oral and Maxillofacial Pathology 2020 24(1):13-14 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Shaleen Chandra Source Type: research

Regenerative medicine - A new horizon for an oral pathologist
PM SunilJournal of Oral and Maxillofacial Pathology 2020 24(1):11-12 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: PM Sunil Source Type: research

COVID - 19 fact sheet for the dental professional
Kannan Ranganathan, T SmithaJournal of Oral and Maxillofacial Pathology 2020 24(1):8-10 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Kannan Ranganathan T Smitha Source Type: research

Coronavirus disease-2019: A brief compilation of facts
Susmita SaxenaJournal of Oral and Maxillofacial Pathology 2020 24(1):5-7 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Susmita Saxena Source Type: research

Current trends and future perspectives of Oral Pathology: Indian Scenario
Yeshwant B RawalJournal of Oral and Maxillofacial Pathology 2020 24(1):3-4 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Yeshwant B Rawal Source Type: research

President & #39;s message
Susmita SaxenaJournal of Oral and Maxillofacial Pathology 2020 24(1):2-2 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: Susmita Saxena Source Type: research

From the editor & #39;s desk
T SmithaJournal of Oral and Maxillofacial Pathology 2020 24(1):1-1 (Source: Journal of Oral and Maxillofacial Pathology)
Source: Journal of Oral and Maxillofacial Pathology - May 8, 2020 Category: ENT & OMF Authors: T Smitha Source Type: research

Fine needle cytology features of an atypical presentation of infectious mononucleosis
Roberto Gerber-Mora, Verónica Peña y Lillo, Ricardo Moreno-Silva, Wilfredo González-ArriagadaJournal of Oral and Maxillofacial Pathology 2020 24(4):139-142 Infectious mononucleosis (IM) is a very common disease, and although in most instances, the patient develops an asymptomatic infection, other patients progress into an array of signs and symptoms that tend to be characteristic of the pathological process, guiding the clinician into choosing the right laboratory examinations under the suspicion of this illness. The most common symptoms are pharyngitis, lymphadenopathies and pyrexia, and the probabilities ...
Source: Journal of Oral and Maxillofacial Pathology - February 28, 2020 Category: ENT & OMF Authors: Roberto Gerber-Mora Ver & #243;nica Pe & #241;a y Lillo Ricardo Moreno-Silva Wilfredo Gonz & #225;lez-Arriagada Source Type: research