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Evaluation of the skin whitening and antioxidant activity of < em > Myracrodum urundeuva < /em > extract (aroeira-do-sert ão)
Nat Prod Res. 2023 Sep 11:1-6. doi: 10.1080/14786419.2023.2254457. Online ahead of print.ABSTRACTMyracrodruon urundeuva, popularly known as 'aroeira-do-sertão', a large tree, with a tall trunk. Belonging to the Anacardiaceae family, it occurs in the 'caatinga' and dry forests of Brazil, from Ceará to the states of Paraná and Mato Grosso do Sul. The present study aimed to analyse the whitening and antioxidant activities of the aqueous extract of the leaves of Myracrodroun urundeuva (AELMU). Inhibition of the tyrosinase enzyme, as well as its copper chelating capacity and antioxidant effect were evaluated. The AELMU (at 2...
Source: Natural Product Research - September 11, 2023 Category: Biochemistry Authors: Érika Sabóia Guerra Diógenes Ant ônia Lais Coelho da Silva Francisco Cirineu das Chagas Neto Edilberto Rocha Silveira Luzia Kalyne Almeida Moreira Leal Roberto Nicolete Tamara Gon çalves de Araújo Source Type: research

Anthropic Impact on the Critically Endangered Melanophryniscus admirabilis (Admirable Redbelly Toad): Evidence from the Presence of Multiresistant Enterobacteriaceae
Curr Microbiol. 2023 Sep 11;80(11):339. doi: 10.1007/s00284-023-03433-7.ABSTRACTMelanophryniscus admirabilis is a microendemic and critically endangered toad, known from a single population. This microendemic species inhabits a small fragment of the Atlantic Forest in South Brazil, an area significantly impacted by hydroelectric power plant projects, livestock farming, agricultural activities, biopiracy, and tourism. Given the exclusive and limited population of M. admirabilis, preserving and conserving this species is of utmost importance in Brazil. Research on this species primarily concentrates on its biology, ecology, ...
Source: Current Microbiology - September 11, 2023 Category: Microbiology Authors: Julia Ienes-Lima Janira Prichula Michelle Abadie M árcio Borges-Martins Ana Paula Guedes Frazzon Source Type: research

The effects of social jetlag and sleep variability on sleepiness in a population-based study: The mediating role of sleep debt
In conclusion, the association between social jetlag and sleepiness was mediated by sleep debt but was not independent of demographic, work, and chronotype variables. This study provides new evidence on the importance of circadian misalignment and sleep debt for sleep health on a population level.PMID:37691450 | DOI:10.1111/jsr.14043
Source: Journal of Sleep Research - September 11, 2023 Category: Sleep Medicine Authors: Guilherme Luiz Fernandes Julia Ribeiro da Silva Vallim V ânia D'Almeida Sergio Tufik Monica Levy Andersen Source Type: research

In vitro evaluation of the cytotoxic and genotoxic effects of Al and Mn in ambient concentrations detected in groundwater intended for human consumption
Ecotoxicol Environ Saf. 2023 Sep 9;264:115415. doi: 10.1016/j.ecoenv.2023.115415. Online ahead of print.ABSTRACTEnvironmental exposure to metals can induce cytotoxic and genotoxic effects in cells and affect the health of the exposed population. To investigate the effects of aluminum (Al) and manganese (Mn), we evaluated their cytogenotoxicity using peripheral blood mononuclear cells (PBMCs) exposed to these metals at previously quantified concentrations in groundwater intended for human consumption. The cell viability, membrane integrity, nuclear division index (NDI), oxidative stress, cell death, cell cycle, and DNA dama...
Source: Ecotoxicology and Environmental Safety - September 11, 2023 Category: Environmental Health Authors: Luiza Flavia Veiga Francisco Debora da Silva Baldivia Bruno do Amaral Crispim Adrivanio Baranoski Syla Maria Farias Ferraz Klafke Edson Lucas Dos Santos Rodrigo Juliano Oliveira Alexeia Barufatti Source Type: research

Anthropic Impact on the Critically Endangered Melanophryniscus admirabilis (Admirable Redbelly Toad): Evidence from the Presence of Multiresistant Enterobacteriaceae
Curr Microbiol. 2023 Sep 11;80(11):339. doi: 10.1007/s00284-023-03433-7.ABSTRACTMelanophryniscus admirabilis is a microendemic and critically endangered toad, known from a single population. This microendemic species inhabits a small fragment of the Atlantic Forest in South Brazil, an area significantly impacted by hydroelectric power plant projects, livestock farming, agricultural activities, biopiracy, and tourism. Given the exclusive and limited population of M. admirabilis, preserving and conserving this species is of utmost importance in Brazil. Research on this species primarily concentrates on its biology, ecology, ...
Source: Current Microbiology - September 11, 2023 Category: Microbiology Authors: Julia Ienes-Lima Janira Prichula Michelle Abadie M árcio Borges-Martins Ana Paula Guedes Frazzon Source Type: research

In vitro evaluation of the cytotoxic and genotoxic effects of Al and Mn in ambient concentrations detected in groundwater intended for human consumption
Ecotoxicol Environ Saf. 2023 Sep 9;264:115415. doi: 10.1016/j.ecoenv.2023.115415. Online ahead of print.ABSTRACTEnvironmental exposure to metals can induce cytotoxic and genotoxic effects in cells and affect the health of the exposed population. To investigate the effects of aluminum (Al) and manganese (Mn), we evaluated their cytogenotoxicity using peripheral blood mononuclear cells (PBMCs) exposed to these metals at previously quantified concentrations in groundwater intended for human consumption. The cell viability, membrane integrity, nuclear division index (NDI), oxidative stress, cell death, cell cycle, and DNA dama...
Source: Ecotoxicology and Environmental Safety - September 11, 2023 Category: Environmental Health Authors: Luiza Flavia Veiga Francisco Debora da Silva Baldivia Bruno do Amaral Crispim Adrivanio Baranoski Syla Maria Farias Ferraz Klafke Edson Lucas Dos Santos Rodrigo Juliano Oliveira Alexeia Barufatti Source Type: research

Anthropic Impact on the Critically Endangered Melanophryniscus admirabilis (Admirable Redbelly Toad): Evidence from the Presence of Multiresistant Enterobacteriaceae
Curr Microbiol. 2023 Sep 11;80(11):339. doi: 10.1007/s00284-023-03433-7.ABSTRACTMelanophryniscus admirabilis is a microendemic and critically endangered toad, known from a single population. This microendemic species inhabits a small fragment of the Atlantic Forest in South Brazil, an area significantly impacted by hydroelectric power plant projects, livestock farming, agricultural activities, biopiracy, and tourism. Given the exclusive and limited population of M. admirabilis, preserving and conserving this species is of utmost importance in Brazil. Research on this species primarily concentrates on its biology, ecology, ...
Source: Current Microbiology - September 11, 2023 Category: Microbiology Authors: Julia Ienes-Lima Janira Prichula Michelle Abadie M árcio Borges-Martins Ana Paula Guedes Frazzon Source Type: research

A predatory social wasp does not avoid nestmates contaminated with a fungal biopesticide
Environ Sci Pollut Res Int. 2023 Sep 11. doi: 10.1007/s11356-023-29770-5. Online ahead of print.ABSTRACTFungus-based biopesticides have been used worldwide for crop pest control as a safer alternative to chemical pesticides such as neonicotinoids. Both agrochemicals can be lethal and may also trigger side effects on the behavioral traits of non-target social insects, which play a crucial role in providing essential biological pest control services in agroecosystems. Here, we evaluated whether a commercial formulation of the entomopathogenic fungus Beauveria bassiana or the neonicotinoid imidacloprid causes mortality in for...
Source: Environmental Science and Pollution Research International - September 11, 2023 Category: Environmental Health Authors: Andr é Rodrigues de Souza Amanda Prato Wilson Franca Sircio Santos Luan Dias Lima Denise Araujo Alves Rodrigo Cupertino Bernardes Eduardo Fernando Santos F ábio Santos do Nascimento Maria Augusta Pereira Lima Source Type: research

Systematic Review and Meta-analysis of laparoscopic radical hysterectomy vs. Robotic assisted radical hysterectomy for early stage cervical cancer
CONCLUSIONS: RRH seems to result in the patient leaving the hospital sooner after surgery. We were unable to find any differences in our ten other outcomes related to complications or efficacy. These findings suggest that the decreased survival seen in minimally invasive RH in previous studies could be due to factors inherent to both LRH and RRH.PROSPERO PROSPECTIVE REGISTRATION NUMBER: CRD42022273727.PMID:37690282 | DOI:10.1016/j.ejogrb.2023.09.002
Source: Reproductive Biology - September 10, 2023 Category: Reproduction Medicine Authors: Greg Marchand Ahmed Taher Masoud Ahmed Abdelsattar Alexa King Giovanna Brazil Hollie Ulibarri Julia Parise Amanda Arroyo Catherine Coriell Sydnee Goetz Carmen Moir Geneva Baruelo Malini Govindan Source Type: research

Ecotoxicology applied to conservation: Potential negative metal and metalloid contamination effects on the homeostatic balance of the critically endangered Brazilian guitarfish, Pseudobatos horkelii (Elasmobranchii: Rhinobatidae)
Chemosphere. 2023 Sep 8:140119. doi: 10.1016/j.chemosphere.2023.140119. Online ahead of print.ABSTRACTMetal contamination poses a significant threat to elasmobranchs, underscoring the need for targeted conservation approaches. The critically endangered Brazilian guitarfish, Pseudobatos horkelii, confronts an array of challenges, notably overexploitation, putting its survival at risk. Our study investigated the potential toxicity arising from arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb) contamination across various adult guitarfish tissues from southeastern Brazil. Serological stress indicators, nutritional metab...
Source: Chemosphere - September 10, 2023 Category: Chemistry Authors: Renata Daldin Leite Natascha Wosnick Amanda Pontes Lopes Tatiana Dillenburg Saint'Pierre Marcelo Vianna Rachel Ann Hauser-Davis Source Type: research

The impact of transformation zone representation on the frequency of abnormal cervical cytological results
CONCLUSION: Samples with TZ representation were associated with higher rates of abnormal results. Health professionals should be regularly trained to understand the weakness of cytological examinations when the TZ is not represented, especially in developing countries.PMID:37688813 | DOI:10.1016/j.ejogrb.2023.08.394
Source: Reproductive Biology - September 9, 2023 Category: Reproduction Medicine Authors: Renata Alfena Zago Deolino Jo ão Camilo-Júnior Solange Correa Garcia Pires D' Ávilla Jos é Cândido Caldeira Xavier-Júnior Source Type: research

Recombinant antigen 5 from Polybia paulista wasp venom (Hymenoptera, Vespidae): Antigen-specific antibody production and functional profile of CD4 < sup > + < /sup > T cells in the immune response
J Immunol Methods. 2023 Sep 7:113557. doi: 10.1016/j.jim.2023.113557. Online ahead of print.ABSTRACTPolybia paulista is a neotropical social wasp related to severe accidents and allergic reactions cases, including anaphylaxis, in southeastern Brazil. Antigen 5 (Poly p 5) is a major allergenic protein from its venom with potential use for component-resolved diagnostic. Therefore, the previous characterization of the immune response profile triggered by Poly p 5 should be evaluated. Recombinant Poly p 5 (rPoly p 5) was used to sensitize BALB/c mice with six weekly intradermal doses, and the specific antibody production and t...
Source: Journal of Immunological Methods - September 9, 2023 Category: Allergy & Immunology Authors: Isabela Oliveira Sandrini Assugeni Murilo Luiz Bazon Lucas Machado Pinto Leonardo Ant ônio Benedito Mainente M árcia Regina Brochetto-Braga Ricardo de Lima Zollner Lu ís Gustavo Romani Fernandes Source Type: research

Mobilome characterization of the beetle Euchroma gigantea (Buprestidae) uncovers multiple long range Tc1-Mariner horizontal transfer events
Gene. 2023 Sep 7:147785. doi: 10.1016/j.gene.2023.147785. Online ahead of print.ABSTRACTTransposable elements (TEs) are mobile repetitive DNA sequences that can transfer horizontally between species. Due to their mutagenic characteristics, TEs are associated with different evolutionary events, including chromosomal rearrangements that are abundant in the beetle Euchroma gigantea. In order to understand more in depth the impact of TEs on the genomic evolution of E. gigantea, we characterized the E. gigantea mobilome and evaluated the horizontal transfer transmission mode of Tc1-Mariner elements. Genomic sequencing data was ...
Source: Gene - September 9, 2023 Category: Genetics & Stem Cells Authors: Igor C Amorim Catarine A A Mello Aline P F élix Crislaine Xavier Gabriel L Wallau Rita C Moura Source Type: research