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Vaccination: Meningitis Vaccine

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Total 210 results found since Jan 2013.

Tropical Travel Trouble 010 Fever, Arthralgia and Rash
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 010 Peer Reviewer: Dr Jennifer Ho, ID physician QLD, Australia You are an ED doc working in Perth over schoolies week. An 18 yo man comes into ED complaining of fever, rash a “cracking headache” and body aches. He has just hopped off the plane from Bali where he spent the last 2 weeks partying, boozing and running amok. He got bitten by “loads” of mosquitoes because he forgot to take insect repellent. On examination he looks miserable,...
Source: Life in the Fast Lane - July 16, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine arthralgia dengue fever rash Source Type: blogs

Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs

Sudden death from acute epiglottitis in a toddler
AbstractThe bacteriumHaemophilus influenzae type b (Hib) can cause severe and life-threatening infections such as epiglottitis and meningitis. The course of the disease can be very rapid, resulting in sudden death. The incidence of Hib-induced epiglottitis in children has declined since the introduction of vaccinations in countries where such vaccinations are routinely administered. We herein present a case involving a 2.5-year-old boy who died suddenly at home. He had developed acute-onset throat and abdominal pain and a high fever. Despite an emergency cricothyrotomy due to a complicated intubation because of a massively...
Source: Forensic Science, Medicine, and Pathology - June 20, 2018 Category: Forensic Medicine Source Type: research

Acute mastoiditis in an Italian pediatric tertiary medical center: a 15 – year retrospective study
ConclusionsDespite the introduction of pneumococcal vaccines, the incidence of acute mastoiditis in our population has not been reduced during the last years. We have to face all the reasons why this condition is still relevant, such as antibiotic resistance, new pathogens involved and a possible role played by the implementations of therapeutic acute otitis media guidelines restricting the use of antibiotics in this disease. A particular attention should be given to younger children where signs and symptoms may be less pronounced, therefore acute otitis media or mastoiditis may be misunderstood and appropriate treatment delayed.
Source: Italian Journal of Pediatrics - June 18, 2018 Category: Pediatrics Source Type: research

The Ethics of Keeping Alfie Alive
By SAURABH JHA Of my time arguing with doctors, 30 % is spent convincing British doctors that their American counterparts aren’t idiots, 30 % convincing American doctors that British doctors aren’t idiots, and 40 % convincing both that I’m not an idiot. A British doctor once earnestly asked whether American physicians carry credit card reading machines inside their white coats. Myths about the NHS can be equally comical. British doctors don’t prostate every morning in deference to the NHS, like the citizens of Oceania sang to Big Brother in Orwell’s dystopia. Nor, in their daily rounds, do they calculate opportun...
Source: The Health Care Blog - May 21, 2018 Category: Consumer Health News Authors: at RogueRad Tags: OP-ED Uncategorized AlfieEvans Source Type: blogs

Grommets (ventilation tubes) for recurrent acute otitis media in children.
CONCLUSIONS: Current evidence on the effectiveness of grommets in children with rAOM is limited to five RCTs with unclear or high risk of bias, which were conducted prior to the introduction of pneumococcal vaccination. Low to very low-quality evidence suggests that children receiving grommets are less likely to have AOM recurrences compared to those managed by active monitoring and placebo medication, but the magnitude of the effect is modest with around one fewer episode at six months and a less noticeable effect by 12 months. The low to very low quality of the evidence means that these numbers need to be interpreted wit...
Source: Cochrane Database of Systematic Reviews - May 9, 2018 Category: General Medicine Authors: Venekamp RP, Mick P, Schilder AG, Nunez DA Tags: Cochrane Database Syst Rev Source Type: research

Celebrities get shingles, too
Follow me on Twitter @RobShmerling Perhaps you heard the news recently that Lin-Manuel Miranda has shingles. Headlines announced this in a variety of ways: Hamilton creator Lin-Manuel Miranda is suffering from shingles (NY DailyNews) Lin-Manuel Miranda has shingles; must be quarantined from his baby (today.com) Lin-Manuel Miranda has shingles, regrets joke about blurred vision (CBS News). Without more information, these headlines might leave you wondering: is this a serious condition? Is it dangerous for children? Can it lead to blindness? What is shingles? The term “shingles” refers to a painful rash caused by infec...
Source: Harvard Health Blog - April 11, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Infectious diseases Skin and Hair Care Vaccines Source Type: blogs

Differences in Immunization Site Pain in Toddlers Vaccinated With Either the 10- or the 13-Valent Pneumococcal Conjugate Vaccine
Conclusions: PCV-10 administration was associated with slightly less acute pain compared with the injection of PCV-13, but the size of the difference was small and is of unknown clinical significance.
Source: The Pediatric Infectious Disease Journal - March 15, 2018 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Vaccinations: More than just kid stuff
Follow me on Twitter @RobShmerling This is the time of year when it’s important to think about flu vaccinations. And there’s good reason for that! The flu causes thousands of preventable hospitalizations and deaths each year. But what about other vaccinations? Do you think of them as something for kids? You aren’t alone. And it’s true, a number of vaccinations are recommended for young children as well as preteens and teenagers. These vaccinations have provided an enormous benefit to public health by preventing diseases that were common and sometimes deadly in the past, including polio, rubella, and whooping cough....
Source: Harvard Health Blog - February 7, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Infectious diseases Prevention Vaccines Source Type: blogs

Interventions Must Be Realistic to Be Useful and Completed in Family Medicine
Being realistic while helping our patients is this issue's theme. Given the volume of tasks required in family medicine, recommendations for improvements in direct care or care measurement cannot just be evidence-based but must also be realistic. On the list of realistic: ordering antipsychotics for symptoms of dementia in the elderly, despite recommendations to not do so; ordering antidepressants without fear that the patient could develop hypertension; mental health care providers in primary care offices; forced choice for opioid management; plus agenda setting for visit efficiency. Not yet realistic: trigger tools to id...
Source: Journal of the American Board of Family Medicine - January 12, 2018 Category: Primary Care Authors: Bowman, M. A., Seehusen, D. A., Victoria Neale, A. Tags: Editors ' Note Source Type: research

Safety and immunogenicity of a novel multiple antigen pneumococcal vaccine in adults: A Phase 1 randomised clinical trial.
CONCLUSIONS: All dose levels were considered safe and well tolerated. There was a statistically significant increase in anti-PnuBioVax IgG titres at the 200 and 500 µg dose levels compared to 50 µg and placebo. TRIAL REGISTRATION NUMBER: NCT02572635https://www.clinicaltrials.gov. PMID: 29132988 [PubMed - as supplied by publisher]
Source: Vaccine - November 10, 2017 Category: Allergy & Immunology Authors: Entwisle C, Hill S, Pang Y, Joachim M, McIlgorm A, Colaco C, Goldblatt D, De Gorguette D'Argoeuves P, Bailey C Tags: Vaccine Source Type: research

Immunogenicity and safety of an inactivated quadrivalent influenza vaccine co-administered with a 23-valent pneumococcal polysaccharide vaccine versus separate administration, in adults ≥50years of age: Results from a phase III, randomized, non-inferiority trial.
CONCLUSION: The IIV4 and PPV23 can be co-administered without reducing antibody responses reflecting protection against influenza or pneumococcal disease. Co-administration of PPV23 at the annual influenza vaccination visit may improve uptake. Comorbidities had no impact on IIV4 immunogenicity, supporting its value in older adults with chronic medical conditions. Clinical Trial Registry Number: NCT02218697. PMID: 28987445 [PubMed - as supplied by publisher]
Source: Vaccine - October 5, 2017 Category: Allergy & Immunology Authors: Ofori-Anyinam O, Leroux-Roels G, Drame M, Aerssens A, Maes C, Amanullah A, Schuind A, Li P, Jain VK, Innis BL Tags: Vaccine Source Type: research

Why Doctors should read books by Nassim Taleb
By SAURABH JHA, MD     “There are some enterprises in which a careful disorderliness is the true method” Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathem...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Why Doctors (And Everybody Else) Should Read Books by Nassim Taleb
By SAURABH JHA, MD “There are some enterprises in which a careful disorderliness is the true method” – Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathematicia...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Risk of bursitis and other injuries and dysfunctions of the shoulder following vaccinations.
Abstract While vaccination injection site adverse reactions are usually mild and transient in nature, several cases of bursitis and other shoulder injuries have been reported in the medical literature. However, these lesions are not included in vaccine label inserts. To identify the characteristics of post-vaccination shoulder injuries and those of patients and involved vaccines, as well as their potential causes, a systematic review of the cases of vaccination-related bursitis and other shoulder injuries reported in the literature and notified to the Spanish Pharmacovigilance System database (FEDRA) have been con...
Source: Vaccine - July 31, 2017 Category: Allergy & Immunology Authors: Martín Arias LH, Sanz Fadrique R, Sáinz Gil M, Salgueiro-Vazquez ME Tags: Vaccine Source Type: research