Risk of bursitis and other injuries and dysfunctions of the shoulder following vaccinations.

Risk of bursitis and other injuries and dysfunctions of the shoulder following vaccinations. Vaccine. 2017 Jul 31;: Authors: Martín Arias LH, Sanz Fadrique R, Sáinz Gil M, Salgueiro-Vazquez ME Abstract While vaccination injection site adverse reactions are usually mild and transient in nature, several cases of bursitis and other shoulder injuries have been reported in the medical literature. However, these lesions are not included in vaccine label inserts. To identify the characteristics of post-vaccination shoulder injuries and those of patients and involved vaccines, as well as their potential causes, a systematic review of the cases of vaccination-related bursitis and other shoulder injuries reported in the literature and notified to the Spanish Pharmacovigilance System database (FEDRA) have been conducted. We found 45 cases of bursitis and other shoulder injuries that appeared following the vaccine intramuscular injection given into the deltoid muscle (37 from the systematic review of the literature, and 8 from the scrutiny in the Spanish Pharmacovigilance System database, FEDRA). All the patients were adult, 71.1% females, with a mean and median age of 53.6years (range: 22-89). The most frequently involved vaccines were influenza and pneumococcal vaccines, respectively; followed by diphtheria-tetanus-pertussis, diphtheria-tetanus toxoid, human papillomavirus, and hepatitis A vaccines. The most frequent shoulder lesion was burs...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research