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Therapy: Stem Cell Therapy
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Total 3267 results found since Jan 2013.
Enhancement of mesenchymal stem cells' chondrogenic potential by type II collagen-based bioscaffolds
CONCLUSIONS: Our data support that type II collagen contributes as a natural bioscaffold enhancing chondrogenesis in both MSC models, thus enhancing the commitment of MSC-based therapeutic approaches in regenerative medicine to target OA and bring therapy closer to the clinical use.PMID:37118382 | DOI:10.1007/s11033-023-08461-x
Source: Mol Biol Cell - April 28, 2023 Category: Molecular Biology Authors: Zoi Piperigkou Dimitra Bainantzou Nadia Makri Eleni Papachristou Aglaia Mantsou Theodora Choli-Papadopoulou Achilleas D Theocharis Nikos K Karamanos Source Type: research
Non-psychoactive Cannabidiol Prevents Osteoporosis in an Animal Model and Increases Cell Viability, Proliferation, and Osteogenic Gene Expression in Human Skeletal Stem and Progenitor Cells
AbstractCannabidiol (CBD), the non-psychoactive component of the Cannabis sativa plant, is marketed as a potential therapeutic agent and has been studied for its roles in reducing inflammation and managing neuropathic pain. Some studies have reported that CB1 and CB2 receptor activation can attenuate and reverse bone loss in experimental animal models. Despite this, little is known about the impact of CBD on fracture healing. We investigated the effects of CBD in vitro using human osteoprogenitor cells and in vivo via murine femur fracture and osteoporosis models. In vitro mesenchymal stem cells were treated with increasin...
Source: Calcified Tissue International - April 24, 2023 Category: Orthopaedics Source Type: research
Measles, mumps, and rubella revaccination in children after completion of chemotherapy and hematopoietic stem cell transplantation: a single-center prospective efficacy and safety analysis
CONCLUSIONS: MMR revaccination is immunogenic for the population. We suggest periodic monitoring of antibody titers, in addition to a booster vaccination, although the optimal timing of booster vaccination remains to be investigated further.PMID:37087716 | DOI:10.1007/s12519-023-00721-x
Source: World Journal of Pediatrics : WJP - April 23, 2023 Category: Pediatrics Authors: Min Wang Qing Yuan Peng-Fei Deng Yi Fei Hua Zhang Fen Zhou Wen-Juan Chen Qing Cao Jing Chen Yi-Jin Gao Source Type: research
Intravenous Injection of Equine Mesenchymal Stem Cells in Dogs with Articular Pain and Lameness: A Feasibility Study
Stem Cells and Development, Ahead of Print.
Source: Stem Cells and Development - April 19, 2023 Category: Stem Cells Authors: Carlien Brondeel Frederik Weekers Lore van Hecke Eva Depuydt Glenn Pauwelyn Geert Verhoeven Nathalie de Bouvr é Peter De Roeck Peter Vandekerckhove Pieter Vanacker Davina B öhm-Geerdink Robert Daems Luc Duchateau Jimmy Saunders Yves Samoy Jan H. Spaas Source Type: research
Limbal stem cell deficiency secondary to systemic daptopotamab deruxtecan (Dato-DXd): A case report and literature review
CONCLUSION: Early detection of the ocular adverse reaction and cessation of the causative drug can avoid permanent ocular morbidity and visual impairment.PMID:37073083 | DOI:10.1177/11206721231169538
Source: European Journal of Ophthalmology - April 18, 2023 Category: Opthalmology Authors: Yi-Chun Chi Li-Yi Chiu Shiuh-Liang Hsu Source Type: research
Review of rehabilitation protocols for brachial plexus injury
Brachial plexus injury (BPI) is one of the most serious peripheral nerve injuries, resulting in severe and persistent impairments of the upper limb and disability in adults and children alike. With the relatively mature early diagnosis and surgical technique of brachial plexus injury, the demand for rehabilitation treatment after brachial plexus injury is gradually increasing. Rehabilitation intervention can be beneficial to some extent during all stages of recovery, including the spontaneous recovery period, the postoperative period, and the sequelae period. However, due to the complex composition of the brachial plexus, ...
Source: Frontiers in Neurology - April 17, 2023 Category: Neurology Source Type: research
A systematic review, umbrella review, and quality assessment on clinical translation of stem cell therapy for knee osteoarthritis: Are we there yet?
CONCLUSIONS: The inefficacy of stem cells, the risk of potential complications, and the limited quality of evidence from current studies precluded any recommendation for using stem cell products in patients with KOA. Clinical translation of stem cell therapies remains baseless and should be cautiously approached until more robust evidence is available. PROSPERO registration number: CRD42022355875.PMID:37061744 | DOI:10.1186/s13287-023-03332-5
Source: Cell Research - April 15, 2023 Category: Cytology Authors: Zhizhong Shang Pingping Wanyan Baolin Zhang Mingchuan Wang Xin Wang Source Type: research
Lung manifestations of sickle-cell disease
Rev Mal Respir. 2023 Apr 12:S0761-8425(23)00107-9. doi: 10.1016/j.rmr.2023.03.002. Online ahead of print.ABSTRACTSickle-cell disease is an autosomal recessive genetic disorder of hemoglobin that causes systemic damage. Hypoxia is the main actor of sickle-cell disease. It initiates acutely the pathogenic cascade leading to tissue damages that in turn induce chronic hypoxia. Lung lesions represent the major risk of morbidity and mortality. Management of sickle-cell disease requires a tight collaboration between hematologists, intensivists and chest physicians. Recurrent episodes of thrombosis and hemolysis characterize the d...
Source: Revue des Maladies Respiratoires - April 14, 2023 Category: Respiratory Medicine Authors: A Hamzaoui S Louhaichi B Hamdi Source Type: research
Leukemia: What Primary Care Physicians Need to Know
Am Fam Physician. 2023 Apr;107(4):397-405.ABSTRACTLeukemia is caused by an abnormal proliferation of hematopoietic stem cells in the bone marrow. The four general subtypes are acute lymphoblastic, acute myelogenous, chronic lymphocytic, and chronic myelogenous. Acute lymphoblastic leukemia primarily occurs in children, whereas the other subtypes are more common in adults. Risk factors include certain chemical and ionizing radiation exposures and genetic disorders. Common symptoms include fever, fatigue, weight loss, joint pain, and easy bruising or bleeding. Diagnosis is confirmed with bone marrow biopsy or peripheral bloo...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Joanne T C Gbenjo Georgia L M McCrary Sarah E Wilson Source Type: research
