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Therapy: Palliative

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Radiation therapy in the last month of life. Association with Aggressive Care at the End of Life
Half of the patients with cancer who undergo radiation therapy do so with palliative intent.
Source: Journal of Pain and Symptom Management - August 30, 2023 Category: Palliative Care Authors: Mellar P Davis, Erin Vanenkevort, Amanda Young, Mark Wojtowicz, Mudit Gupta, Braxton Lagerman, Edward Liu, Heath Mackley, Rajiv Panikkar Tags: Original Article Source Type: research

"I Just Don't Feel Heard": A Case Study on Opioid Use Disorder and Pain Management
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-6. doi: 10.1080/15360288.2023.2250340. Online ahead of print.ABSTRACTThe nation's opioid epidemic requires a paradigm shift in the way patients with co-occurring opioid use disorder are treated during episodes of acute pain. Patients are often introduced to prescription opioids after an extremity fracture or sprain or resulting from musculoskeletal back, abdominal, or dental pain. Opioid naive patients who receive their first opioid prescription on discharge from the emergency department may be more likely to develop chronic opioid use compared to patients receiving non-opioi...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Aila Malik Peter D Vu A Sarah Cohen Vishal Bansal Morgan R Cowan Gregory M Blazek Tiffany Champagne-Langabeer Source Type: research

Suspected Buprenorphine-Precipitated Opioid Withdrawal following Intercourse: A Case Report
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-3. doi: 10.1080/15360288.2023.2250344. Online ahead of print.ABSTRACTBuprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known about the pharmacokinetics of drugs in seminal fluid, pH is thought to play an integral role. Limited evidence exists surrounding cervical absorption of drugs via seminal fluid transmission. This also prompts survey...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Davene Lynch Lyndsey Chitty Brittany Johnson Amie L Hoefnagel Source Type: research

"I Just Don't Feel Heard": A Case Study on Opioid Use Disorder and Pain Management
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-6. doi: 10.1080/15360288.2023.2250340. Online ahead of print.ABSTRACTThe nation's opioid epidemic requires a paradigm shift in the way patients with co-occurring opioid use disorder are treated during episodes of acute pain. Patients are often introduced to prescription opioids after an extremity fracture or sprain or resulting from musculoskeletal back, abdominal, or dental pain. Opioid naive patients who receive their first opioid prescription on discharge from the emergency department may be more likely to develop chronic opioid use compared to patients receiving non-opioi...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Aila Malik Peter D Vu A Sarah Cohen Vishal Bansal Morgan R Cowan Gregory M Blazek Tiffany Champagne-Langabeer Source Type: research

Suspected Buprenorphine-Precipitated Opioid Withdrawal following Intercourse: A Case Report
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-3. doi: 10.1080/15360288.2023.2250344. Online ahead of print.ABSTRACTBuprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known about the pharmacokinetics of drugs in seminal fluid, pH is thought to play an integral role. Limited evidence exists surrounding cervical absorption of drugs via seminal fluid transmission. This also prompts survey...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Davene Lynch Lyndsey Chitty Brittany Johnson Amie L Hoefnagel Source Type: research

"I Just Don't Feel Heard": A Case Study on Opioid Use Disorder and Pain Management
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-6. doi: 10.1080/15360288.2023.2250340. Online ahead of print.ABSTRACTThe nation's opioid epidemic requires a paradigm shift in the way patients with co-occurring opioid use disorder are treated during episodes of acute pain. Patients are often introduced to prescription opioids after an extremity fracture or sprain or resulting from musculoskeletal back, abdominal, or dental pain. Opioid naive patients who receive their first opioid prescription on discharge from the emergency department may be more likely to develop chronic opioid use compared to patients receiving non-opioi...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Aila Malik Peter D Vu A Sarah Cohen Vishal Bansal Morgan R Cowan Gregory M Blazek Tiffany Champagne-Langabeer Source Type: research

Suspected Buprenorphine-Precipitated Opioid Withdrawal following Intercourse: A Case Report
J Pain Palliat Care Pharmacother. 2023 Aug 28:1-3. doi: 10.1080/15360288.2023.2250344. Online ahead of print.ABSTRACTBuprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known about the pharmacokinetics of drugs in seminal fluid, pH is thought to play an integral role. Limited evidence exists surrounding cervical absorption of drugs via seminal fluid transmission. This also prompts survey...
Source: Journal of Pain and Palliative Care Pharmacotherapy - August 28, 2023 Category: Palliative Care Authors: Davene Lynch Lyndsey Chitty Brittany Johnson Amie L Hoefnagel Source Type: research

Impact of short-course palliative radiotherapy on pancreatic cancer-related pain: Prospective phase II non-randomized PAINPANC trial
Clinical evidence is limited regarding palliative radiotherapy for relieving pancreatic cancer-related pain. We prospectively investigated pain response following short-course palliative radiotherapy in patients with moderate-to-severe pancreatic cancer-related pain.
Source: International Journal of Radiation Oncology * Biology * Physics - August 28, 2023 Category: Radiology Authors: C. Paola Tello Valverde, Gati Ebrahimi, Mirjam A. Sprangers, Konstantinos Pateras, Anna M.E. Bruynzeel, Marc Jacobs, Johanna W. Wilmink, Marc G. Besselink, Hans Crezee, Geertjan van Tienhoven, Eva Versteijne Tags: Clinical Investigation Source Type: research

Impact of an Institution-wide Goals of Care Program on the Timing of Referrals to Outpatient Palliative Care
Palliative care has received increased interest since the COVID-19 pandemic due to its role in guiding goals of care (GOC) discussions.
Source: Journal of Pain and Symptom Management - August 27, 2023 Category: Palliative Care Authors: Akhila Reddy, Joannis Baez Gonz ález, Ali Rizvi, Nico Nortje, Shalini Dalal, Ali Haider, Jaya Sheela Amaram-Davila, Patricia Bramati, Minxing Chen, David Hui, Eduardo Bruera Tags: Brief Report Source Type: research

Strategies to Improve Perioperative Palliative Care Integration for Seriously Ill Veterans
Seriously ill patients are at higher risk for adverse surgical outcomes. Palliative care (PC) interventions for seriously ill surgical patients are associated with improved quality of patient care and patient-centered outcomes, yet, they are underutilized perioperatively.
Source: Journal of Pain and Symptom Management - August 27, 2023 Category: Palliative Care Authors: Karleen F. Giannitrapani, Marzena Sasnal, Matthew McCaa, Adela Wu, Arden M. Morris, Natalie B. Connell, Rebecca A. Aslakson, Yael Schenker, Scott Shreve, Karl A. Lorenz Tags: Original Article Source Type: research

Psychosocial well-being of siblings of pediatric patients in palliative home care
Despite the proposed high burden of siblings of children and adolescents with life limiting conditions receiving pediatric palliative care (PPC) at home, little is known about their psychosocial well-being.
Source: Journal of Pain and Symptom Management - August 27, 2023 Category: Palliative Care Authors: Lars Dinkelbach, Marc K öhler, Maren Galushko, Leonie Pieper, Michaela Kuhlen, Mareike Danneberg, Oliver Dechert, Laura Trocan, Gisela Janßen Tags: Original Article Source Type: research

Sedative drug-use in Denmark, 2000 to 2019: a nationwide drug utilization study
ConclusionIn Denmark different central regulations have influenced prescription practice toward more restrictive use of Z-drugs and benzodiazepines, except for hypnotic benzodiazepine prescriptions increased after the introduction of special palliative care. An increase in use of newer sedative drugs, however, indicates that the regulations do not remove the need for sedative drugs in the population.
Source: Social Psychiatry and Psychiatric Epidemiology - August 26, 2023 Category: Psychiatry Source Type: research

More time in a community setting: A service evaluation of the impact of intrathecal drug delivery systems on place of care of patients with cancer pain
CONCLUSION: In patients with advanced cancer, the successful establishment of intrathecal analgesia is associated with more time in the community and a lower morphine equivalent daily dose at end of life. The study has low numbers, and the sample was retrospectively selected. Nevertheless, these findings suggest the initial investment of time in an inpatient setting may be beneficial. Further research is required, using larger, prospective studies of patient outcomes in this setting.PMID:37632373 | DOI:10.1177/02692163231191548
Source: Palliative Medicine - August 26, 2023 Category: Palliative Care Authors: Alison Mitchell Lesley Somerville Nicola Williams Jonathan McGhie Alex McConnachie Gordon McGinn Jiyoung Lee Source Type: research