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Total 140 results found since Jan 2013.

First study demonstrating speckle tracking echocardiography has prognostic value in patients with idiopathic inflammatory myopathies
AbstractTo measure left ventricular (LV) global longitudinal strain (GLS) using speckle tracking echocardiography in idiopathic inflammatory myopathy (IIM) patients and to determine whether the LV GLS predicts outcomes in those patients. Prospective study consisted of a cross-sectional phase with 61 IIM patients and 32 individuals without IIM and longitudinal phase, in which patients were divided into two subgroups: 26 with reduced LV GLS and 35 with normal LV GLS; patients were followed for a mean of 25  months, and the occurrence of cardiovascular events and criteria for IIM activity were compared. The mean LV GLS (18.5...
Source: The International Journal of Cardiovascular Imaging - August 17, 2023 Category: Radiology Source Type: research

Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research

Genes, Vol. 14, Pages 1539: Danon Disease: Entire LAMP2 Gene Deletion with Unusual Clinical Presentation & mdash;Case Report and Review of the Literature
This report describes a 42-year-old father and his 3-year-old daughter presenting with mild manifestations of the disease. The father has normal intellectual development and normal physical activity. At the age of 13, he was diagnosed with mild ventricular pre-excitation known as Wolf–Parkinson–White syndrome (WPWs), very mild and mostly asymptomatic cardiomyopathy and left ventricular hypertrophy, and at about the age of 25 presented with visual impairment due to cone–rod dystrophy. His daughter showed normal development and very mild asymptomatic electrocardiographic WPWs abnorma...
Source: Genes - July 27, 2023 Category: Genetics & Stem Cells Authors: Adel Shalata Marina Bar-Shai Yarin Hadid Muhammad Mahroum Hila Mintz Zaher Eldin Shalata Evgeny Radzishevsky Jacob Genizi Avraham Lorber Tamar Ben-Yosef Liat Yaniv Tags: Article Source Type: research

The association between C-peptide and atrial cardiomyopathy in nondiabetic adults: results from NHANES III
AbstractSerum C-peptide exhibits various biological activities. The relationship between C-peptide and atrial cardiomyopathy remains unknown. We aimed to investigate the association between C-peptide level and atrial cardiomyopathy in nondiabetic adults. Our study enrolled 4578 participants without diagnosed diabetes from the Third National Health and Nutrition Examination Survey (NHANES III). Atrial cardiomyopathy was defined as a deep terminal negative P wave in V1 below − 100 µV (more negative), according to the electrocardiogram. The participants were categorized into low C-peptide (≤ 1.46 nmol/L) and high C-...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

Comprehensive pathological and genetic investigation of three young adult myotonic dystrophy type 1 patients with sudden unexpected death
Conclusion and relevanceThe present study showed varied heart morphology in young adults with DM1 and sudden death. Synergistic effects of various genetic factors other than CTG repeats may increase the risk of sudden cardiac death in DM1 patients, even if signs of cardiac and skeletal muscle involvement are mild. Comprehensive genetic investigations, other than CTG repeat assessment, may be useful to estimate the risk of sudden cardiac death in DM1 patients.
Source: Journal of Neurology - July 11, 2023 Category: Neurology Source Type: research

The association between C-peptide and atrial cardiomyopathy in nondiabetic adults: results from NHANES III
AbstractSerum C-peptide exhibits various biological activities. The relationship between C-peptide and atrial cardiomyopathy remains unknown. We aimed to investigate the association between C-peptide level and atrial cardiomyopathy in nondiabetic adults. Our study enrolled 4578 participants without diagnosed diabetes from the Third National Health and Nutrition Examination Survey (NHANES III). Atrial cardiomyopathy was defined as a deep terminal negative P wave in V1 below − 100 µV (more negative), according to the electrocardiogram. The participants were categorized into low C-peptide (≤ 1.46 nmol/L) and high C-...
Source: Heart and Vessels - June 24, 2023 Category: Cardiology Source Type: research

Association of abnormal p ‐wave parameters with brain mri morphology: the atherosclerosis risk in communities neurocognitive study (ARIC‐NCS)
Conclusion: In this exploratory analysis of a US community-based cohort, ECG surrogates of atrial myopathy are associated with higher prevalence of brain infarcts and microhemorrhage, suggesting subclinical vascular brain injury as a possible mechanism underlying the association of atrial myopathy with dementia.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - March 17, 2023 Category: Cardiology Authors: Jorge L. Reyes, Faye L. Norby, Yuekai Ji, Wendy Wang, Romil Parikh, Michael J. Zhang, Niki C. Oldenburg, Pamela L. Lutsey, Clifford R. Jack, Michelle Johansen, Rebecca F. Gottesman, Josef Coresh, Thomas Mosley, Elsayed Z. Soliman, Alvaro Alo Tags: ORIGINAL ARTICLE Source Type: research

Association of abnormal p-wave parameters with brain mri morphology: the atherosclerosis risk in communities neurocognitive study (ARIC-NCS)
CONCLUSION: In this exploratory analysis of a US community-based cohort, ECG surrogates of atrial myopathy are associated with higher prevalence of brain infarcts and microhemorrhage, suggesting subclinical vascular brain injury as a possible mechanism underlying the association of atrial myopathy with dementia. This article is protected by copyright. All rights reserved.PMID:36924350 | DOI:10.1111/pace.14687
Source: Atherosclerosis - March 16, 2023 Category: Cardiology Authors: Jorge L Reyes Faye L Norby Yuekai Ji Wendy Wang Romil Parikh Michael J Zhang Niki C Oldenburg Pamela L Lutsey Clifford R Jack Michelle Johansen Rebecca F Gottesman Josef Coresh Thomas Mosley Elsayed Z Soliman Alvaro Alonso Lin Yee Chen Source Type: research

Multimodality Screening For (Peri)Myocarditis In Newly Diagnosed Idiopathic Inflammatory Myopathies: A Cross-Sectional Study
CONCLUSIONS: A diagnostic algorithm for detection of (peri)myocarditis in adult IIM may consist of sequential testing with high-sensitivity cardiac troponins and CMR.PMID:36683515 | DOI:10.3233/JND-221582
Source: Atherosclerosis - January 23, 2023 Category: Cardiology Authors: Johan Lim Hannah A W Walter Rianne A C M de Bruin-Bon Myrthe C Jarings R Nils Planken Wouter E M Kok Joost Raaphorst Yigal M Pinto Ahmad S Amin S Matthijs Boekholdt Anneke J van der Kooi Source Type: research

Prevalence and clinical significance of electrocardiographic signs of atrial myopathy in rheumatoid arthritis: results from the EDRA study
CONCLUSIONS: Electrocardiographic markers of atrial myopathy are independently associated with RA. Further studies with larger sample size and longer follow-up are needed to determine whether the increased prevalence of atrial myopathy contributes to the increased risk of atrial fibrillation and stroke in this group.PMID:36622121 | DOI:10.55563/clinexprheumatol/d9l4lt
Source: Clinical and Experimental Rheumatology - January 9, 2023 Category: Rheumatology Authors: Giuseppe D Sanna Matteo Piga Anna Piga Olga Falco Enrico Ponti Alberto Cauli Alberto Floris Arduino A Mangoni Gavino Casu Giuseppe De Luca Gian Luca Erre EDRA Study Group Source Type: research