Filtered By:
Infectious Disease: Hepatitis

This page shows you your search results in order of date. This is page number 5.

Order by Relevance | Date

Total 76 results found since Jan 2013.

Hepatitis E induced severe myositis
This article is protected by copyright. All rights reserved.
Source: Muscle and Nerve - October 30, 2015 Category: Internal Medicine Authors: Annerose M. Mengel, Werner Stenzel, Andreas Meisel, Carsten Büning Tags: Case of the Month Source Type: research

Immune-Mediated Necrotizing Myopathy: Update on Diagnosis and Management
Abstract The idiopathic inflammatory myopathies (IIMs) comprise a group of autoimmune disorders that target skeletal muscle. They are characterized by typical laboratory and clinical features including muscle weakness, elevated muscle enzymes, characteristic histopathology of muscle biopsies, as well as electromyography abnormalities. The IIMs are divided into polymyositis, dermatomyositis, inclusion body myositis, nonspecific myositis, and immune-mediated necrotizing myopathy (IMNM). IMNM is distinguished by the absence of primary inflammation on muscle biopsy. IMNM may be associated with myositis-specific autoa...
Source: Current Rheumatology Reports - October 30, 2015 Category: Rheumatology Source Type: research

Thymoma associated with autoimmune diseases: 85 cases and literature review
Conclusions We describe here the long-term follow-up of a large series of AD related to thymoma. Our results confirm previous data concerning AD occurrence in patients with thymoma and suggest that preexisting autoimmunity is not a risk factor for developping autoimmune manifestations after thymectomy.
Source: Autoimmunity Reviews - September 25, 2015 Category: Allergy & Immunology Source Type: research

Telbivudine in liver transplant recipients: Renal protection does not overcome the risk of polyneuropathy and myopathy
In conclusion, although it seems to have a favorable effect in the improvement of renal function and to be effective in the prevention of HBV recurrence, the high risk of polyneuropathy and myopathy hamper the use of telbivudine in LT recipients. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - April 2, 2015 Category: Transplant Surgery Authors: Ilker Turan, Suna Yapali, Fikret Bademkiran, Timur Kose, Soner Duman, Murat Sozbilen, Fulya Gunsar, Galip Ersoz, Ulus Salih Akarca, Omer Ozutemiz, Zeki Karasu Tags: Original Articles Source Type: research

Necrotizing Myopathies: An Update
Abstract: Necrotizing myopathy is defined by the predominant pathological feature of necrosis of muscle fibers in the absence of substantial lymphocytic inflammatory infiltrates. Most commonly necrotizing myopathies are divided into immune mediated (IMNM) and nonimmune mediated (NIMNM). IMNM has been associated with anti–signal recognition particle antibodies, connective tissue diseases, cancer, post-statin exposure with 3-hydroxy-3-methylglutaryl-coenzyme A antibodies, and viral infections including HIV and hepatitis C. NIMNM is linked to medications and toxic exposures. Both IMNM and NIMNM are typically characterized b...
Source: Journal of Clinical Neuromuscular Disease - February 20, 2015 Category: Neurology Tags: Review Article Source Type: research

Lamivudine/telbivudine-associated neuromyopathy: neurogenic damage, mitochondrial dysfunction and mitochondrial DNA depletion
Conclusions MtDNA depletion results in mitochondrial dysfunction in the lamivudine/telbivudine-associated neuromyopathy. Myopathy was characterised by mitochondrial dysfunction accompanied with neurogenic damage due to axonal neuropathy. Ultrastructure changes of mitochondria included vacuolisation, simplification of the cristae and homogenised matrix.
Source: Journal of Clinical Pathology - October 16, 2014 Category: Pathology Authors: Xu, H., Wang, Z., Zheng, L., Zhang, W., Lv, H., Jin, S., Yuan, Y. Tags: Liver disease, Open access, Hepatitis and other GI infections, Muscle disease, Musculoskeletal syndromes, Hepatitis (sexual health), Clinical diagnostic tests Original article Source Type: research

Continuous Venovenous Hemodiafiltration for Hyperlactatemia Caused by Telbivudine in a Patient with Chronic Hepatitis B: A Case Report and Update Review
Abstract Though telbivudine has been reported causing myopathy and elevating creatine kinase (CK), there is still few reports on telbivudine and hyperlactatemia in patients with chronic hepatitis B. Here we report the case of hyperlactaemia during telbivudine treatment. A 26‐year‐old Chinese origin man has been received telbivudine antiviral treatment for chronic hepatitis B since 3 July, 2011, and found the CK was 68 U/L before the anti‐viral treatment. After 3 months of therapy, he generally felt nausea and vomited frequently. The CK checked in local clinic was up to 222 U/L (upper limit of normal 170 U/L). However...
Source: Chinese Journal of Digestive Diseases - June 1, 2014 Category: Gastroenterology Authors: Yan‐Hong Wang, Ben‐Quan Wu, Hui Liu Tags: Case Report Source Type: research

Novel LAMP2 mutations in Chinese patients with Danon disease cause varying degrees of clinical severity.
This study described two Chinese cases of Danon disease in order to broaden the phenotypic and genetic spectrum. Methods: Clinical data were collected and LAMP2 mutations were analyzed. Results: Patient A had fluctuating limb weakness during 6 months follow-up and was diagnosed with drug-induced myopathy due to anti-hepatitis B therapy with lamivudine. However, the first muscle biopsy with large cytoplasmic vacuoles confused the diagnosis and led to the second biopsy that allowed for the final diagnosis. Patient B had severe cardiac disturbances leading to sudden death. Molecularly, patient A harbored a synonymous mutation...
Source: Clinical Neuropathology - April 2, 2014 Category: Pathology Authors: Luo SS, Xi JY, Cai S, Zhao CB, Lu JH, Zhu WH, Lin J, Qiao K, Wang Y, Ye ZR Tags: Clin Neuropathol Source Type: research

Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma.
Abstract Dermatomyositis is an idiopathic inflammatory myopathy with typical cutaneous manifestations. It has been proposed that dermatomyositis may be caused by autoimmune responses to viral infections. Previous studies have shown an association between dermatomyositis and malignant tumors such as ovarian cancer, lung cancer, and colorectal cancer. However, a chronic hepatitis B virus (HBV) infection associated with dermatomyositis and hepatocellular carcinoma (HCC) has been very rarely reported. Here, we report a rare case of dermatomyositis coinciding with HBV-associated HCC. A 55-year-old male was confirmed to...
Source: The Korean Journal of Internal Medicine - March 1, 2014 Category: Internal Medicine Authors: Yang SY, Cha BK, Kim G, Lee HW, Kim JG, Chang SK, Kim HJ Tags: Korean J Intern Med Source Type: research

Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment
Abstract Oral nucleoside/nucleotide analogues (NAs) are the mainstay of therapy for patients with chronic hepatitis B and are generally well tolerated. Despite this, the safety profile of NAs is of paramount importance since the majority of patients will require long‐term treatment. All NAs can potentially affect human DNA polymerase with decrease in mitochondrial DNA, leading to manifestations of mitochondrial toxicity. As a class effect, therefore, NAs can potentially cause extrahepatic conditions, such as myopathy, nephropathy, neuropathy, and lactic acidosis. Indeed, effects on muscles, including myopathy and creatin...
Source: Journal of Gastroenterology and Hepatology - February 19, 2014 Category: Gastroenterology Authors: James Fung, Wai‐Kay Seto, Ching‐Lung Lai, Man‐Fung Yuen Tags: Review Source Type: research

Chronic hepatitis in a patient with rigid spine myopathy: Cause or just an association?
PMID: 24918145 [PubMed - in process]
Source: The Turkish Journal of Gastroenterology - February 1, 2014 Category: Gastroenterology Authors: Ozkan H, Arslan M, Kabacam G, Tas A, Ozgür G, Kaygusuz G, Ekinci C, Serdaroğlu A, Köklü S Tags: Turk J Gastroenterol Source Type: research

Extra‐hepatic Effects of Nucleoside and Nucleotide Analogues in Chronic Hepatitis B Treatment
Abstract Oral nucleoside/nucleotide analogues (NAs) are the mainstay of therapy for patients with chronic hepatitis B, and are generally well tolerated. Despite this, the safety profile of NAs is of paramount importance since the majority of patients will require long‐term treatment. All NAs can potentially affect human DNA polymerase with decrease in mitochondrial DNA, leading to manifestations of mitochondrial toxicity. As a class effect therefore, NAs can potentially cause extra‐hepatic conditions such as myopathy, nephropathy, neuropathy, and lactic acidosis. Indeed, effects on muscles including myopathy and creati...
Source: Journal of Gastroenterology and Hepatology - December 27, 2013 Category: Gastroenterology Authors: James Fung, Wai‐Kay Seto, Ching‐Lung Lai, Man‐Fung Yuen Tags: Solicited Review Source Type: research

Entecavir‐associated myopathy: a case report and literature review
Conclusion: Patients who receive NA therapy should be closely monitored for myopathic side effects. © 2013 Wiley Periodicals, Inc.
Source: Muscle and Nerve - November 12, 2013 Category: Internal Medicine Authors: Kai Yuan, Guochun Wang, Zhenguo Huang, Bing Lin, Huiqiong Zhou, Xin Lu Tags: Research Article Source Type: research

Virological Response and Muscular Adverse Events during Long-Term Clevudine Therapy in Chronic Hepatitis B Patients
Conclusions: Long-term clevudine monotherapy is effective for suppression of serum HBV DNA level and normalization of serum alanine amino transaminase levels, but associated with occurrence of rtM204I mutation. Clevudine-induced muscular adverse events are not uncommon, although they are totally reversible after cessation of the treatment. Muscular adverse events and serum CK level should be carefully monitored during long-term treatment with clevudine.
Source: Hepatitis Monthly - March 31, 2013 Category: Infectious Diseases Source Type: research

Efficacy of Entecavir Switching Therapy in Chronic Hepatitis B Patients with Clevudine-induced Myopathy.
Conclusions: In chronic hepatitis B patients experiencing clevudine-induced myopathy, switching to entecavir 0.5 mg per day showed a resolution of myopathy and adequate viral suppression. (Korean J Gastroenterol 2013;61:30-36). PMID: 23354347 [PubMed - in process]
Source: Korean J Gastroenter... - January 25, 2013 Category: Gastroenterology Authors: Lee JW, Lee YJ, Lee JJ, Kim JH, Jung YK, Kwon OS, Choi DJ, Kim YS, Kim JH Tags: Korean J Gastroenterol Source Type: research