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Total 203 results found since Jan 2013.

Magnetic resonance findings in subacute combined degeneration
ABSTRACT In the 1890s, one of Charcot ’ s most important prot égés, Dr. Paul Richer (1849 – 1933), drew and sculpted a series of representations of the main types of nerve pathology. That series included drawings of pleomorphic hysterical crises and sculptures depicting patients suffering from labio-glosso-laryngeal paralysis and myopathy, as well as Parkinson ’ s disease. Richer was a resident at La Salp êtrière and, in 1882, became head of the Charcot museum. Early in his career, despite having no formal artistic training, he could represent masterfully, in drawings and sculptures, people ’ s tragic suffering...
Source: Arquivos de Neuro-Psiquiatria - July 20, 2017 Category: Neurology Source Type: research

Acute Epstein-Barr virus encephalitis in an immunocompetent adolescent patient
ABSTRACT In the 1890s, one of Charcot ’ s most important prot égés, Dr. Paul Richer (1849 – 1933), drew and sculpted a series of representations of the main types of nerve pathology. That series included drawings of pleomorphic hysterical crises and sculptures depicting patients suffering from labio-glosso-laryngeal paralysis and myopathy, as well as Parkinson ’ s disease. Richer was a resident at La Salp êtrière and, in 1882, became head of the Charcot museum. Early in his career, despite having no formal artistic training, he could represent masterfully, in drawings and sculptures, people ’ s tragic suffering...
Source: Arquivos de Neuro-Psiquiatria - July 20, 2017 Category: Neurology Source Type: research

Burning pain attacks and red skin in a young woman
ABSTRACT In the 1890s, one of Charcot ’ s most important prot égés, Dr. Paul Richer (1849 – 1933), drew and sculpted a series of representations of the main types of nerve pathology. That series included drawings of pleomorphic hysterical crises and sculptures depicting patients suffering from labio-glosso-laryngeal paralysis and myopathy, as well as Parkinson ’ s disease. Richer was a resident at La Salp êtrière and, in 1882, became head of the Charcot museum. Early in his career, despite having no formal artistic training, he could represent masterfully, in drawings and sculptures, people ’ s tragic suffering...
Source: Arquivos de Neuro-Psiquiatria - July 20, 2017 Category: Neurology Source Type: research

Common therapeutic approaches of sarcopenia in the elderly and uremic myopathy.
Abstract The gradual loss of weight and function of muscle in patients with chronic kidney disease as in the elderly impacts the quality of life. Early management should help slow the functional limitation. Physical activity is the first therapy to propose that ensures stability of muscle mass and improved function. Resistance training programs have proven effective but are not yet widely available in nephrology units. The nutritional management should not be forgotten because there is a resistance to anabolism and protein intake should be involved in physical activity program. Associated treatments should not be ...
Source: Nephrologie and Therapeutique - June 9, 2017 Category: Urology & Nephrology Authors: Chauveau P, Moreau K, Lasseur C, Combe C, Aparicio M Tags: Nephrol Ther Source Type: research

Genome-wide Association Study of Susceptibility to Particulate Matter –Associated QT Prolongation
Conclusions: The findings suggest that biologically plausible genetic factors may alter susceptibility to PM10-associated QT prolongation in populations protected by the U.S. Environmental Protection Agency’s National Ambient Air Quality Standards. Independent replication and functional characterization are necessary to validate our findings. https://doi.org/10.1289/EHP347 Received: 11 April 2016 Revised: 07 September 2016 Accepted: 19 September 2016 Published: 08 June 2017 Address correspondence to R. Gondalia, Department of Epidemiology, University of North Carolina, 137 E. Franklin St., Chapel Hill, NC 27514. Te...
Source: EHP Research - June 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Effects of different aerobic exercise frequencies on streptozotocin –nicotinamide‐induced type 2 diabetic rats: Continuous versus short bouts and weekend warrior exercises
ConclusionsThe results of the study emphasize the effects of training on inflammation, increased oxidative stress, myopathy, and mitochondrial damage in a rat model of T2DM, and demonstrate that there is no major difference between exercise modalities provided that the total duration of exercise remains the same.
Source: Journal of Diabetes - June 2, 2017 Category: Endocrinology Authors: Nuray Alaca, Serap Uslu, Guldal Gulec Suyen, Umit Ince, Mustafa Serteser, H ızır Kurtel Tags: Original Article Source Type: research

Effects of leucine supplementation and resistance training on myopathy of diabetic rats
In conclusion, 5% leucine supplementation combined with resistance training has the potential to attenuate muscle loss and motor performance decrements in diabetic rats, at least in part through increased protein synthesis. Leucine and resistance training has the potential to attenuate muscle loss and motor performance decrements in diabetic rats.
Source: Physiological Reports - May 23, 2017 Category: Physiology Authors: Carlos Eduardo C. Martins, Vanessa B. de S. Lima, Brad J. Schoenfeld, Julio Tirapegui Tags: Original Research Source Type: research

Effects of different aerobic exercise frequencies on  streptozotocin‐nicotinamide‐induced type 2 diabetic rats: continuous versus short bouts and weekend warrior exercises
ConclusionsThe results of our study emphasized the impact of training on inflammation, increased oxidative stress, myopathy and mitochondrial damage in the rat model of streptozotocin‐nicotinamide‐induced T2DM, and demonstrated that there is no major difference between exercise modalities provided that the total duration of exercise remains the same.
Source: Journal of Diabetes - April 20, 2017 Category: Endocrinology Authors: Nuray Alaca, Serap Uslu, Guldal Gulec Suyen, Umit Ince, Mustafa Serteser, H ızır Kurtel Tags: Original Article Source Type: research

Intervention Effect on Fellow Muscle Biopsy Reading Accuracy in Inflammatory Myositis (P2.124)
Conclusions:Improved accuracy in the interpretation of IIM pathology amongst inexperienced muscle biopsy readers can support the use of a limited standardized educational program.Disclosure: Dr. Hamasaki has nothing to disclose. Dr. Jawdat has nothing to disclose. Dr. Kimple has nothing to disclose. Dr. Dimachkie has received personal compensation for activities with Pfizer, Depomed, Merck, CSL-Behring, Nufactor, Biomarin, Baxter and Catalyst as a consultant and/or speaker. Dr. Pasnoor has nothing to disclose. Dr. Statland has received personal compensation for activities with Sarepta, ATYR Bristol Meyers Squib, Acceleron,...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Hamasaki, A., Jawdat, O., Kimple, D., Dimachkie, M., Pasnoor, M., Statland, J., Barohn, R., Glenn, M., Herbelin, L. Tags: Myopathies & amp;amp; Myasthenia Gravis II Source Type: research

Performance test evaluation of intra-rater and inter-rater reliability among examiners of histopathological findings in myositis subtypes (P2.132)
Conclusions:This study explores intra and inter reliability for diagnosing DM, PM and NM by muscle biopsy specimens. If consistency can be shown in muscle biopsy interpretation by studying intra-rater and inter-rater reliability in fellows studying neuromuscular medicine, this will help to validate the use of muscle biopsy for diagnostic use in medical professionals with limited training.Disclosure: Dr. Kimple has nothing to disclose. Dr Barohn received personal compensation for activities with Grifols & Genzyme as a member of the Speakers Bureau and NuFactor as a consultant. Dr. Dimachkie has received personal compens...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kimple, D., Barohn, R., Dimachkie, M., Pasnoor, M., Glenn, M., Herbelin, L., Statland, J., Jawdat, O. Tags: Myopathies & amp;amp; Myasthenia Gravis II Source Type: research

Fitness and mobility training in patients with Intensive Care Unit-acquired muscle weakness (FITonICU): study protocol for a randomised controlled trial
Critical illness myopathy (CIM) and polyneuropathy (CIP) are a common complication of critical illness. Both cause intensive-care-unit-acquired (ICU-acquired) muscle weakness (ICUAW) which increases morbidity ...
Source: Trials - November 24, 2016 Category: Journals (General) Authors: Jan Mehrholz, Simone Thomas, Jane H. Burridge, Andr é Schmidt, Bettina Scheffler, Ralph Schellin, Stefan Rückriem, Daniel Meißner, Katja Mehrholz, Wolfgang Sauter, Ulf Bodechtel and Bernhard Elsner Source Type: research

Development and validation of algorithms for the detection of statin myopathy signals from electronic medical records.
This article is protected by copyright. All rights reserved. PMID: 27706800 [PubMed - as supplied by publisher]
Source: Clinical Pharmacology and Therapeutics - October 4, 2016 Category: Drugs & Pharmacology Authors: Chan SL, Tham MY, Tan SH, Loke C, Foo B, Fan Y, Ang PS, Brunham LR, Sung C Tags: Clin Pharmacol Ther Source Type: research

Insight into the training of patients with idiopathic inflammatory myopathy.
Abstract Using current recommended treatment, a majority of patients with idiopathic inflammatory myopathy develop muscle impairment and poor health. Beneficial effects of exercise have been reported on muscle performance, aerobic capacity and health in chronic polymyositis and dermatomyositis, as well as in active disease and inclusion body myositis to some extent. Importantly, randomized controlled trials indicate that improved health and decreased clinical disease activity could be mediated through increased aerobic capacity. Recently, reports seeking pathomechanisms of the underlying effects of exercise on ske...
Source: Orvosi Hetilap - August 31, 2016 Category: Journals (General) Authors: Váncsa A Tags: Orv Hetil Source Type: research

Clinical Reasoning: A 33-year-old man with cardiomyopathy and myopathy
An 18-year-old Hmong man sought medical care because of worsening performance on military training exercises. He had a previous syncopal episode with prompt recovery. His medical and developmental history were otherwise unremarkable. A chest radiograph revealed cardiomegaly and, after further cardiac tests, he was diagnosed with postinfectious or idiopathic cardiomyopathy. His cardiac function deteriorated and heart transplantation was pursued. During preoperative evaluation, his serum creatine kinase (CK) was noted to be persistently elevated in the 4,000s, prompting further investigation, but since he was not weak or oth...
Source: Neurology - August 21, 2016 Category: Neurology Authors: Foster, L. A., Courville, E. L., Manousakis, G. Tags: Lipidoses, Muscle disease, Cardiac, All Genetics RESIDENT AND FELLOW SECTION Source Type: research

Effects of High Intensity Interval Exercise Training on Skeletal Myopathy of Chronic Heart Failure
• High intensity interval exercise reverses skeletal muscle alternations of HF.• Anabolic effects may be attributed to responses of the IGF-1 bioregulation system.• High intensity interval program seemed to be superior to induce muscle hypertrophy.
Source: Journal of Cardiac Failure - June 16, 2016 Category: Cardiology Authors: Georgios Tzanis, Anastassios Philippou, Eleftherios Karatzanos, Stavros Dimopoulos, Elisavet Kaldara, Emmeleia Nana, Theodoros Pitsolis, Dimitra Rontogianni, Michael Koutsilieris, Serafim Nanas Tags: Clinical Investigation Source Type: research