Genome-wide Association Study of Susceptibility to Particulate Matter –Associated QT Prolongation

Conclusions:
The findings suggest that biologically plausible genetic factors may alter susceptibility to PM10-associated QT prolongation in populations protected by the U.S. Environmental Protection Agency’s National Ambient Air Quality Standards. Independent replication and functional characterization are necessary to validate our findings. https://doi.org/10.1289/EHP347

Received: 11 April 2016
Revised: 07 September 2016
Accepted: 19 September 2016
Published: 08 June 2017
Address correspondence to R. Gondalia, Department of Epidemiology, University of North Carolina, 137 E. Franklin St., Chapel Hill, NC 27514. Telephone: [phone]. Fax: [phone]. E-mail: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP347).
The authors declare they have no actual or potential competing financial interests.
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Supplemental Material PDF (972 KB)

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Source: EHP Research - June 8, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research