Filtered By:
Condition: Polymyositis

This page shows you your search results in order of date. This is page number 9.

Order by Relevance | Date

Total 420 results found since Jan 2013.

Lymphocyte immunophenotyping in inflammatory myositis: a review
Purpose of review This is a comprehensive review of the current knowledge on predominant immune cell phenotypes involved in idiopathic inflammatory myopathies (IIM). Recent findings Major circulating immune cell subpopulations described in IIM encompass the lymphocyte compartment. An unbalance in T cell subsets seems to consistently affect the peripheral and muscle compartment, with a predominance of CD4+ T and B cells in dermatomyositis, CD8+ T cells in polymyositis/inclusion body myositis (IBM) and novel findings highlighting novel proinflammatory T subsets, that is, CD8+Tbet+ and CD28− T cells across differ...
Source: Current Opinion in Rheumatology - October 9, 2021 Category: Rheumatology Tags: MYOSITIS AND MYOPATHIES: Edited by Andrea Doria, Anna Ghirardello and Mariele Gatto Source Type: research

Characteristics of idiopathic inflammatory myopathies with novel myositis-specific autoantibodies
CONCLUSIONS: Identification of MSAs might help to predict the clinical course of the autoimmune myopathy and malignancy risk. However, these antibodies were absent in about 30% of patients with typical PM or DM manifestations, which encourages further research in this area.PMID:34610217 | DOI:10.17219/acem/141181
Source: Clinical Lung Cancer - October 5, 2021 Category: Cancer & Oncology Authors: Anna Rams Joanna Kosa łka-Węgiel Piotr Kuszmiersz Aleksandra Matyja-Bednarczyk Stanis ław Polański Lech Zar ęba Stanis ława Bazan-Socha Source Type: research

Autoimmune & inflammatory nmd
Anti-transcription intermediary factor 1 γ (TIF1γ) antibodies are one of the myositis-specific antibodies frequently detected in dermatomyositis (DM). To elucidate the characteristics of anti-TIF1γ antibody-positive myositis, we extracted cases with anti-TIF1γ antibodies from idiopathic inflammatory myopathy (IIM) patients who underwen t muscle biopsy from 2008 to 2019, and analyzed the clinicopathological findings. We found 87 cases of IIM (40 DM, 3 polymyositis, 25 immune-mediated necrotizing myopathy, 14 antisynthetase syndrome, and 5 nonspecific myositis), among which anti-TIF1γ antibodies were positive in 13 case...
Source: Neuromuscular Disorders - September 19, 2021 Category: Neurology Authors: A. Yamanaka, N. Eura, M. Yamaoka, M. Ozaki, T. Shiota, H. Nanaura, K. Sugie Source Type: research

New insights into cellular or muscle function
Analysis of human muscle diseases highlights the role of mitochondrial dysfunction in the skeletal muscle. Our previous work revealed that diverse upstream events correlated with altered mitochondrial proteome in human muscle biopsies. However, several proteins showed relatively unchanged expression suggesting that posttranslational modifications, mainly protein phosphorylation could influence their activity and regulate mitochondrial processes. We conducted mitochondrial phosphoprotein profiling, by proteomics approach, of healthy human skeletal muscle (n=10) and three muscle diseases (n=10 each): Dysferlinopathy, polymyo...
Source: Neuromuscular Disorders - September 19, 2021 Category: Neurology Authors: B. Sunitha, M. Kumar, N. Gowthami, S. Unni, N. Gayathri, T. Keshava Prasad, A. Nalini, K. Polavarapu, S. Vengalil, K. Veeramani Preethish, B. Padmanabhan, M. Srinivas Bharath Source Type: research

Diagnostic Accuracy of Anti-CN1A on the Diagnosis of Inclusion Body Myositis. A Hierarchical Bivariate and Bayesian Meta-analysis
In this study, we investigated the diagnostic accuracy of anti-CN1A antibodies for sporadic IBM in comparison with other inflammatory myopathies, autoimmune disorders, motor neurone disease, using a hierarchical bivariate approach, and a Bayesian model taking into account the variable prevalence. The results of the present analysis show that anti-CN1A antibodies have moderate sensitivity, and despite having high specificity, they are not useful biomarkers for the diagnosis of IBM, polymyositis or dermatomyositis, other autoimmune conditions, or neuromuscular disorders. Neither the hierarchical bivariate nor the Bayesian an...
Source: Journal of Clinical Neuromuscular Disease - August 28, 2021 Category: Neurology Tags: Review Article Source Type: research

MR imaging findings of musculoskeletal involvement in microscopic polyangiitis: a comparison with inflammatory myopathy
ConclusionIntramuscular hyperintensity and fascial hyperintensity have always been observed in MPA, and the predominantly affected sites were usually the fascial regions. Compared with PM/DM, fascial hyperintensity and diffuse subcutaneous fat hyperintensity were more frequent in MPA.
Source: La Radiologia Medica - August 20, 2021 Category: Radiology Source Type: research

Chest pain in a mid-aged woman, not simply myopericarditis: a case report of anti-Ku positive polymyositis
Anti-Ku is a rare antibody which can be positive in some rheumatic diseases and it might be related to cardiac involvement. Polymyositis is an inflammatory myopathy, and its cardiac involvement seldom presents...
Source: BMC Cardiovascular Disorders - August 6, 2021 Category: Cardiology Authors: Weiping Tan, Bin Dong, Jincui Gu, Yang Peng and Ruicong Xue Tags: Case report Source Type: research

Anti-Ku Antibody-Related Scleroderma-Polymyositis Overlap Syndrome Associated With Hypothyroid Myopathy
No abstract available
Source: JCR: Journal of Clinical Rheumatology - August 1, 2021 Category: Rheumatology Tags: Images Source Type: research

Muscular pathological features in patients with myasthenia gravis
CONCLUSION: Muscle histological abnormalities mimicking myopathy may be found in MG patients. Patients with different antibodies present with different muscle histopathology. PM pattern pathology is a special pattern of muscle histology in MG that should not be misdiagnosed. Our study has extended the muscle pathological features of MG in addition to deepening the understanding of MG.PMID:34236310 | DOI:10.5414/NP301382
Source: Clinical Neuropathology - July 8, 2021 Category: Pathology Authors: Lingya Qiao Yutong Zhang Rui Ban Ying Lin Chuanqiang Pu Qiang Shi Source Type: research