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Specialty: Biomedical Science
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Total 5325 results found since Jan 2013.
SARS-CoV-2 egress from Vero cells: a morphological approach
This study aimed to shed light on the morphological features of SARS-CoV-2 egress by utilizing transmission and high-resolution scanning electron microscopy, along with serial electron tomography, to describe the route of nascent virions towards the extracellular medium. Electron microscopy revealed that the clusters of viruses in the paracellular space did not seem to result from collective virus release. Instead, virus accumulation was observed on incurved areas of the cell surface, with egress primarily occurring through individual vesicles. Additionally, our findings showed that the emission of long membrane projection...
Source: Histochemistry and Cell Biology - September 22, 2023 Category: Biomedical Science Source Type: research
Nanoparticles: a breakthrough in COVID-19 prevention, diagnosis and treatment
Arch Med Sci. 2021 Oct 15;19(5):1410-1420. doi: 10.5114/aoms/142103. eCollection 2023.ABSTRACTCoronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), declared a global pandemic by the World Health Organization (WHO). The three key principles in management of the COVID-19 pandemic are prevention, early detection and targeted treatment. Vaccine-based prevention together with early detection has already proven its efficacy in controlling the pandemic. Early detection of infected patients could substantially accelerate the implementation of treatment,...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Aleksandra Skwarek Aleksandra G ąsecka Mi łosz J Jaguszewski Łukasz Szarpak Tomasz Dzieci ątkowski Krzysztof J Filipiak Source Type: research
Reduction of lymphocyte count at early stage elevates severity and death risk of COVID-19 patients: a hospital-based case-cohort study
CONCLUSIONS: Older COVID-19 patients are more susceptible to lymphopenia. Multiple organ injuries were more serious in COVID-19 patients with lymphopenia. Lymphopenia at an early stage aggravates the severity and elevates the death risk of COVID-19 patients.PMID:37732034 | PMC:PMC10507779 | DOI:10.5114/aoms.2020.99006
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Jun Fei Lin Fu Ying Li Hui-Xian Xiang Ying Xiang Meng-Die Li Fang-Fang Liu De-Xiang Xu Hui Zhao Source Type: research
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Arch Med Sci. 2021 Apr 23;19(5):1327-1359. doi: 10.5114/aoms/135703. eCollection 2023.ABSTRACTCOVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system. COVID-19 (coronavirus) and other enveloped viruses including severe acute respiratory syndrome (SARS-CoV-1 of 2002-2003) and Middle East respiratory syndrome (MERS; 2012-ongoing) and hepatitis B and C (HBV and HCV) can be inactivated by AA, γ-linolenic acid (GLA, dihomo-GLA (DGLA), eicosapentaenoic ...
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Undurti N Das Source Type: research
Impact of COVID-19 pandemic on Tuberculosis and HIV services in Ghana: An interrupted time series analysis
ConclusionThis study demonstrated that the COVID-19 pandemic negatively impacted TB case notifications and HIV testing and counselling services, However, ART initiation was generally not impacted during the first year of the pandemic. Proactive approaches aimed at actively finding the thousands of individuals with TB who were missed in 2020 and increasing HIV testing and counselling and subsequent treatment initiations should be prioritised.
Source: PLoS One - September 20, 2023 Category: Biomedical Science Authors: Eric Osei Source Type: research
Roles of the interaction with children and families in mediating the association between digital health literacy and well-being of early childhood teachers in Portugal: A cross-sectional study
ConclusionThese findings suggest that improving ECE teachers ´ DHL could have a positive effect on their well-being and their interactions with children. Therefore, it is recommended to develop health promotion practices aimed at enhancing DHL among ECE teachers. Additionally, integrating DHL contents and competencies more prominently into the qualification, further education and training of ECE teachers may help equip them with the necessary skills to access and apply health information effectively. This, in turn, can enhance interactions with children and contribute to their overall well-being.
Source: PLoS One - September 20, 2023 Category: Biomedical Science Authors: Rafaela Ros ário Source Type: research
Clinical Utility of Sero-Immunological Responses Against SARS-CoV-2 Nucleocapsid Protein During Subsequent Prevalence of Wild-Type, Delta Variant, and Omicron Variant
In conclusion, nucleocapsid antibody provides instructive clues about the immunogenicity of nucleocapsid proteins by different seroconversion rates and titers according to the severity of infection, host immune status, and different variants of concern.PMID:37724496 | PMC:PMC10506902 | DOI:10.3346/jkms.2023.38.e292
Source: Journal of Korean Medical Science - September 19, 2023 Category: Biomedical Science Authors: Beomki Lee Jae-Hoon Ko Jin Yang Baek Haein Kim Kyungmin Huh Sun Young Cho Cheol-In Kang Doo Ryeon Chung Kyong Ran Peck Eun-Suk Kang Source Type: research
Animal efficacy study of a plant extract complex (BEN815) as a potential treatment for COVID-19
by Moon Ho Do, Hua Li, Su Yeon Cho, Subin Oh, Ju Hwan Jeong, Min-Suk Song, Jong-Moon Jeong
In a short time, several types of injectable and oral therapeutics have been developed and used to effectively manage patients with coronavirus disease 2019 (COVID-19). BEN815 is an improved mixture of three extracts (Psidium guajava,Camellia sinensis, andRosa hybrida) recognized by the Ministry of Food and Drug Safety of Korea as a health food ingredient that alleviates allergic rhinitis. The current animal efficacy study was performed to assess its probability of improving COVID-19 symptoms. BEN815 treatment significantly increase...
Source: PLoS One - September 14, 2023 Category: Biomedical Science Authors: Moon Ho Do Source Type: research
Influence of Intolerance of Uncertainty on Preoccupation With Coronavirus Disease 2019 Among Frontline Nursing Professionals: Mediating Role of Reassurance-Seeking Behavior and Adherence to Physical Distancing
CONCLUSION: During the pandemic, there may be a strong association between reassurance-seeking behavior, viral anxiety, and a heightened preoccupation with COVID-19 among frontline healthcare workers. Thus, from the early stages of infectious disease, a psychological support team for medical staff responding to the disease should be established, and periodic evaluations should be conducted to identify high-risk groups.PMID:37698207 | DOI:10.3346/jkms.2023.38.e282
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Eulah Cho Jihoon Hong Harin Kim C Hyung Keun Park Youjin Hong Jangho Park Jin Yong Jun Seockhoon Chung Source Type: research
Risk Factors for the Prescription of Ineffective Antiviral Candidates for COVID-19 During the Early Pandemic Period in Korea
CONCLUSION: Ineffective antiviral agents were prescribed to a substantial number of patients during the first year of the COVID-19 pandemic in Korea. Treatment with these ineffective drugs tended to be prolonged in severely ill patients and in primary and public hospitals.PMID:37698205 | DOI:10.3346/jkms.2023.38.e280
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Eunyoung Lee Seungyeon Kim Sun Young Lee Joo Jeong Jihwan Bang Juhwan Oh Sang Do Shin Nam Joong Kim Pyoeng Gyun Choe Myoung-Don Oh Source Type: research
Influence of Intolerance of Uncertainty on Preoccupation With Coronavirus Disease 2019 Among Frontline Nursing Professionals: Mediating Role of Reassurance-Seeking Behavior and Adherence to Physical Distancing
CONCLUSION: During the pandemic, there may be a strong association between reassurance-seeking behavior, viral anxiety, and a heightened preoccupation with COVID-19 among frontline healthcare workers. Thus, from the early stages of infectious disease, a psychological support team for medical staff responding to the disease should be established, and periodic evaluations should be conducted to identify high-risk groups.PMID:37698207 | PMC:PMC10497351 | DOI:10.3346/jkms.2023.38.e282
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Eulah Cho Jihoon Hong Harin Kim C Hyung Keun Park Youjin Hong Jangho Park Jin Yong Jun Seockhoon Chung Source Type: research
Risk Factors for the Prescription of Ineffective Antiviral Candidates for COVID-19 During the Early Pandemic Period in Korea
CONCLUSION: Ineffective antiviral agents were prescribed to a substantial number of patients during the first year of the COVID-19 pandemic in Korea. Treatment with these ineffective drugs tended to be prolonged in severely ill patients and in primary and public hospitals.PMID:37698205 | PMC:PMC10497349 | DOI:10.3346/jkms.2023.38.e280
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Eunyoung Lee Seungyeon Kim Sun Young Lee Joo Jeong Jihwan Bang Juhwan Oh Sang Do Shin Nam Joong Kim Pyoeng Gyun Choe Myoung-Don Oh Source Type: research
Influence of Intolerance of Uncertainty on Preoccupation With Coronavirus Disease 2019 Among Frontline Nursing Professionals: Mediating Role of Reassurance-Seeking Behavior and Adherence to Physical Distancing
CONCLUSION: During the pandemic, there may be a strong association between reassurance-seeking behavior, viral anxiety, and a heightened preoccupation with COVID-19 among frontline healthcare workers. Thus, from the early stages of infectious disease, a psychological support team for medical staff responding to the disease should be established, and periodic evaluations should be conducted to identify high-risk groups.PMID:37698207 | PMC:PMC10497351 | DOI:10.3346/jkms.2023.38.e282
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Eulah Cho Jihoon Hong Harin Kim C Hyung Keun Park Youjin Hong Jangho Park Jin Yong Jun Seockhoon Chung Source Type: research
