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Total 5325 results found since Jan 2013.

Two Years of Experience and Methodology of Korean COVID-19 Living Clinical Practice Guideline Development
CONCLUSION: We provided timely recommendations on living schemes and disseminated them to the public, policymakers and various stakeholders using webpages and social media. Although the output was successful, there were some limitations. The rigor of development issues, urgent timelines for public dissemination, education for new developers, and spread of several new COVID-19 variants have worked as barriers. Therefore, we must prepare systematic processes and funding for future pandemics.PMID:37309700 | PMC:PMC10261709 | DOI:10.3346/jkms.2023.38.e195
Source: Journal of Korean Medical Science - June 13, 2023 Category: Biomedical Science Authors: Miyoung Choi Hyeon-Jeong Lee Su-Yeon Yu Jimin Kim Jungeun Park Seungeun Ryoo Inho Kim Dong Ah Park Young Kyung Yoon Joon-Sung Joh Sunghoon Park Ki Wook Yun Chi-Hoon Choi Jae-Seok Kim Sue Shin Hyun Kim Kyungmin Huh In-Seok Jeong Soo-Han Choi Sung Ho Hwang Source Type: research

Effect of Wearing Personal Protective Equipment (PPE) for COVID-19 Treatment on Blood Culture Contamination: Implication for Optimal PPE Strategies
J Korean Med Sci. 2023 Jun 12;38(23):e180. doi: 10.3346/jkms.2023.38.e180.ABSTRACTThe personal protective equipment (PPE) used to minimize exposure to hazards can hinder healthcare workers from performing sophisticated procedures. We retrospectively reviewed 77,535 blood cultures (202,012 pairs) performed in 28,502 patients from January 2020 to April 2022. The contamination rate of all blood cultures was significantly elevated in the coronavirus disease 2019 ward at 4.68%, compared to intensive care units at 2.56%, emergency rooms at 1.13%, hematology wards at 1.08%, and general wards at 1.07% (All of P < 0.001). This f...
Source: Journal of Korean Medical Science - June 13, 2023 Category: Biomedical Science Authors: Jae Hyeon Park Taek Soo Kim Chan Mi Lee Chang Kyung Kang Wan Beom Park Nam Joong Kim Pyoeng Gyun Choe Myoung-Don Oh Source Type: research

Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer
Aging (Albany NY). 2023 Jun 7;15. doi: 10.18632/aging.204755. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic. The severity of COVID-19 increases with each decade of life, a phenomenon that suggest that organismal aging contributes to the fatality of the disease. In this regard, we and others have previously shown that COVID-19 severity correlates with shorter telomeres, a molecular determinant of aging, in patient's leukocytes. Lung injury is a predominant feature of acute SARS-CoV-2 infection that can furthe...
Source: Aging - June 9, 2023 Category: Biomedical Science Authors: Paula Mart ínez Ra úl Sánchez-Vazquez Arpita Saha Maria S Rodriguez-Duque Sara Naranjo-Gonzalo Joy S Osorio-Chavez Ana V Villar-Ramos Maria A Blasco Source Type: research

Standardization of in-house anti-IgG and IgA ELISAs for the detection of COVID-19
by Kamonthip Rungrojcharoenkit, Rungarun Suthangkornkul, Darunee Utennam, Darunee Buddhari, Soontorn Pinpaiboon, Duangrat Mongkolsirichaikul, Stefan Fernandez, Anthony R. Jones, Thomas S. Cotrone, Taweewun Hunsawong Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). RT-PCR detection of viral RNA represents the gold standard method for diagnosis of COVID-19. However, multiple diagnostic tests are needed for acute disease diagnosis and ass essing immunity during the COVID-19 outbreak. Here, we developed in-house anti-RBD IgG and IgA enzyme-linked immun...
Source: PLoS One - June 9, 2023 Category: Biomedical Science Authors: Kamonthip Rungrojcharoenkit Source Type: research

A review of venous thromboembolism in India
Indian J Med Res. 2023 Apr;157(4):281-292. doi: 10.4103/ijmr.ijmr_1538_22.ABSTRACTVenous thromboembolism (VTE), which entails the formation of a thrombus (blood clot) in a vein, has a significant disease burden worldwide. While VTE has traditionally been considered to predominantly affect Caucasian populations, recent studies have indicated a gradual shift in the disease burden towards Asian populations, with added significance of it being a key driver of post-operative mortality. It is imperative to develop a sound understanding of the various factors that affect VTE in stratified local populations. However, there is a gl...
Source: The Indian Journal of Medical Research - June 7, 2023 Category: Biomedical Science Authors: Heena Tabassum Rohan Chakraborty Nabendu Sekhar Chatterjee Source Type: research

Within-Host Evolution of SARS-CoV-2 in a B-Cell Depleted Patient With Successful Treatment
J Korean Med Sci. 2023 Jun 5;38(22):e175. doi: 10.3346/jkms.2023.38.e175.ABSTRACTProlonged viral shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an immunocompromised host is a challenge as the treatment and infection control for chronic coronavirus disease 2019 infection is not well established and there is a potential risk of new variants emerging. A 48-year-old woman who underwent chemotherapy, including rituximab and steroid, had reactivation of SARS-CoV-2 68 days after the virus was first detected. She successfully recovered after receiving convalescent plasma and intravenous immunoglobulin....
Source: Journal of Korean Medical Science - June 5, 2023 Category: Biomedical Science Authors: Yae Jee Baek Gemma Park Jun Yong Choi Eun Jin Kim Bryan Inho Kim Jin Gwack Ji Ye Jung Source Type: research

A Nationwide Survey of mRNA COVID-19 Vaccinee's Experiences on Adverse Events and Its Associated Factors
CONCLUSION: Approximately 90% of participants reported AEs following mRNA COVID-19 vaccination. Substantial factors, including vaccine type (mRNA-1273), female sex, and dermatologic diseases were associated with AEs. Our findings could aid policymakers in establishing vaccination strategies tailored to those potentially susceptible to AEs.PMID:37272559 | DOI:10.3346/jkms.2023.38.e170
Source: Journal of Korean Medical Science - June 5, 2023 Category: Biomedical Science Authors: Dongwon Yoon Ha-Lim Jeon Yunha Noh Young June Choe Seung-Ah Choe Jaehun Jung Ju-Young Shin Source Type: research