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Procedure: Lower Endoscopy
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Total 241 results found since Jan 2013.
Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps.
In this study we investigate the cytokine profile in CRSwNPs that underwent FESS for the first time and recurrent CRSwNPs.
METHODS: Tissue samples (n = 21) of CRSwNP patients with no recurrence after the first surgery were randomly selected out of 131 primary FESS surgeries and compared with tissue samples (n = 15) from patients who had a first and second surgery because of recurrence. Interleukin (IL)-1beta, IgE, specific IgE, IL-5, interferon (IFN) gamma, IL-6, IL-17, transforming growth factor (TGF) beta1, and myeloperoxidase were measured on tissue homogenates.
RESULTS: Levels of IgE, specific IgE to Staphylo...
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Van Zele T, Holtappels G, Gevaert P, Bachert C Tags: Am J Rhinol Allergy Source Type: research
Does Helicobacter pylori Protect against Eosinophilic Esophagitis in Children?
ConclusionA reversed association between Hp and EoE was found in a cohort of West Virginia children. The possible explanations for these findings are discussed.
Source: Helicobacter - April 1, 2014 Category: Gastroenterology Authors: Yoram Elitsur, Baraa Alabd Alrazzak, Deborah Preston, Yulia Demetieva Tags: Original Article Source Type: research
Postoperative irrigation therapy after sinonasal tumor surgery.
CONCLUSION: Although corticosteroid irrigations have become routine for managing inflammatory sinus disease at our center, their use after tumor surgery does not appear to be warranted. The inflammatory healing process after tumor surgery differs from CRS inflammation and may explain the observed findings.
PMID: 24717955 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2014 Category: ENT & OMF Authors: Jo HW, Dalgorf DM, Snidvongs K, Sacks R, Harvey RJ Tags: Am J Rhinol Allergy Source Type: research
Evaluation of olfaction in patients with pemphigus vulgaris.
CONCLUSION: PV causes olfactory dysfunction leading to eventual hyposmia that decreases quality of life. We suggest that olfactory testing be included in PV evaluation for the diagnosis and treatment of hyposmia, when necessary.
PMID: 24717939 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2014 Category: ENT & OMF Authors: Meric A, Dogan R, Veyseller B, Su O, Ozucer B, Tugrul S, Ozturan O Tags: Am J Rhinol Allergy Source Type: research
The impact of comorbid migraine on quality‐of‐life outcomes after endoscopic sinus surgery
ConclusionPatients with comorbid migraine and CRS are more likely to have less severe evidence of disease and worse preoperative baseline QOL scores. This may imply that comorbid migraine disorder, in the setting of CRS, compels these patients to seek surgical management earlier in the disease process. Regardless, ESS provides comparable improvement for both patients with and without comorbid migraine.
Level of Evidence2c. Laryngoscope, 2014
Source: The Laryngoscope - February 20, 2014 Category: ENT & OMF Authors: Adam S. DeConde, Jess C. Mace, Timothy L. Smith Tags: Allergy/Rhinology Source Type: research
Helminth therapy (worms) for induction of remission in inflammatory bowel disease.
CONCLUSIONS: Currently, there is insufficient evidence to allow any firm conclusions regarding the efficacy and safety of helminths used to treat patients with IBD. The evidence for our primary efficacy outcomes in this review comes from one small study and is of low quality due to serious imprecision. We do not have enough evidence to determine whether helminths are safe when used in patients with UC and CD. Further RCTs are required to assess the efficacy and safety of helminth therapy in IBD.
PMID: 24442917 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 20, 2014 Category: Journals (General) Authors: Garg SK, Croft AM, Bager P Tags: Cochrane Database Syst Rev Source Type: research
Azithromycin add-on therapy in high-risk postendoscopic sinus surgery patients failing corticosteroid irrigations: A clinical practice audit.
CONCLUSION: A significant subgroup of high-risk patients showing disease recurrence after ESS despite topical corticosteroid therapy may respond to the addition of AZI as part of their therapy. These findings suggest that topical steroid-unresponsive CRS may represent a distinct entity and that alternate anti-inflammatory agents may be required for optimal management.
PMID: 24598145 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - December 13, 2013 Category: ENT & OMF Authors: Maniakas A, Desrosiers M Tags: Am J Rhinol Allergy Source Type: research
Surgical treatment of nasal polyposis: A comparison between cutting forceps and microdebrider.
CONCLUSION: The manual instrument allowed for a significantly lower recurrence incidence but yielded a higher rate of synechia formation compared with the microdebrider. Only asthma was significantly associated with a poorer clinical outcome, and gender, age, allergy, and eosinophilia did not affect the surgical prognosis.
PMID: 24274215 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2013 Category: ENT & OMF Authors: Tirelli G, Gatto A, Spinato G, Tofanelli M Tags: Am J Rhinol Allergy Source Type: research
Serum 25-hydroxyvitamin D levels are lower in chronic rhinosinusitis with nasal polyposis and are correlated with disease severity in Taiwanese patients.
CONCLUSION: A significantly lower vitamin D level was found in a group of Taiwanese CRSwNP patients, which revealed an association with greater nasal polyp size. Serum vitamin D levels could be added to the routine workup of patients suffering from CRS and these data could be used to potentially help determine the disease severity.
PMID: 24274207 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2013 Category: ENT & OMF Authors: Wang LF, Lee CH, Chien CY, Chen JY, Chiang FY, Tai CF Tags: Am J Rhinol Allergy Source Type: research
Complications of primary and revision functional endoscopic sinus surgery for chronic rhinosinusitis
ConclusionThe rate of major complications (0.36%) associated with primary FESS is lower than earlier reports. The rate of major complications following revision FESS (0.46%) was found to be similar to primary cases. IGS, insurance status, age, and extent of surgery were found to be associated with an increased risk of major complications following FESS.
Level of Evidence2C. Laryngoscope, 2013
Source: The Laryngoscope - October 9, 2013 Category: ENT & OMF Authors: James G. Krings, Dorina Kallogjeri, Andre Wineland, Kenneth G. Nepple, Jay F. Piccirillo, Anne E. Getz Tags: Allergy/Rhinology Source Type: research
Deficient glucocorticoid induction of anti-inflammatory genes in nasal polyp fibroblasts of asthmatic patients with and without aspirin intolerance
The objective of this study was to elucidate whether nasal polyp fibroblasts from patients with/without AIA have alterations in the GR signaling pathway that might explain the relative insensitivity of these patients to glucocorticoids.
Source: Journal of Allergy and Clinical Immunology - September 3, 2013 Category: Allergy & Immunology Authors: Laura Fernández-Bertolín, Joaquim Mullol, Mireya Fuentes-Prado, Isam Alobid, Jordi Roca-Ferrer, César Picado, Laura Pujols Tags: Letters to the Editor Source Type: research
Systemic effects and safety of triamcinolone-impregnated nasal packing after endoscopic sinus surgery: A randomized, double-blinded, placebo-controlled study.
CONCLUSIONS: TA-impregnated nasal dressings suppress serum cortisol levels during the early postoperative period. This systemic effect was recovered gradually and normalized 10 days after the operation.
PMID: 24119605 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Hong SD, Kim JH, Dhong HJ, Kim HY, Chung SK, Chang YS, Sohn JH Tags: Am J Rhinol Allergy Source Type: research
The potential role of hyaluronic acid in postoperative radiofrequency surgery for chronic inferior turbinate hypertrophy.
CONCLUSION: The results of this prospective study suggest a role of HA as a supportive treatment for faster improvement of nasal respiration, also minimizing patients' discomfort in postoperative nasal surgery, promoting nasal mucosa healing in postoperative RFVTR for inferior turbinate hypertrophy.
PMID: 23710960 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2013 Category: ENT & OMF Authors: Manuele C, Giacomo C, Valeria F, Antonino I, Francesco M, Peter B, Ranko M, Fabrizio S Tags: Am J Rhinol Allergy Source Type: research
The Editors' Choice
Chronic rhinosinusitis (CRS) is a common inflammatory condition of the paranasal sinuses with an unclear cause. The factors and illnesses associated with the development of CRS have not been examined longitudinally. In this issue Tan et al (p 1350) study the epidemiology of CRS using a case-control study on incident CRS cases. By using 10 years of electronic health records from the Geisinger Clinic, which serves a primary care population of a geographically large and demographically stable population in central Pennsylvania, the authors were able to examine patterns of diagnoses and health resource use preceding a new di...
Source: Journal of Allergy and Clinical Immunology - May 1, 2013 Category: Allergy & Immunology Authors: Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI Tags: The Editors' choice Source Type: research
Juvenile nasopharyngeal angiofibroma: A Systematic Review and Comparison of Endoscopic, Endoscopic‐Assisted, and Open Resection in 1047 Cases
Conclusions:In this study, endoscopic resection had a significantly lower intraoperative blood loss and lower recurrence rate when compared to open resection. However, there was no difference in recurrence rate when analyzing the IPD and controlling for Radkowski/Sessions grading. Therefore, further large‐scale studies may be required to fully elucidate treatment options.
Source: The Laryngoscope - March 11, 2013 Category: ENT & OMF Authors: Zain Boghani, Qasim Husain, Vivek V. Kanumuri, Mohemmed N. Khan, Saurin Sangvhi, James K. Liu, Jean Anderson Eloy Tags: Allergy/Rhinology Source Type: research
