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Procedure: Skin Biopsy

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Total 252 results found since Jan 2013.

Characterization of a group of children with eosinophilic esophagitis in Cali, Colombia
CONCLUSIONS: The majority of patients with EoE were females. The most frequent symptom was abdominal pain. Endoscopic abnormalities were also observed frequently, and the prevalence of other allergic diseases (especially rhinitis) and allergenic sensitization (especially to mites) was high.PMID:37169558 | DOI:10.15586/aei.v51i3.729
Source: Allergologia et Immunopathologia - May 11, 2023 Category: Allergy & Immunology Authors: Laura Del Mar V ásquez Carlos Daniel Serrano Margarita Pe ña Veronica Botero Diana Quimbayo Rafael Milan és Laura Torres-Canchala Manuela Olaya Source Type: research

Lymphangioleiomyomatosis and Other Cystic Lung Diseases
Cysts and cavities in the lung are commonly encountered on chest imaging. It is necessary to distinguish thin-walled lung cysts ( ≤2 mm) from cavities and characterize their distribution as focal or multifocal versus diffuse. Focal cavitary lesions are often caused by inflammatory, infectious, or neoplastic processes in contrast to diffuse cystic lung diseases. An algorithmic approach to diffuse cystic lung disease can help narrow the differential diagnosis, and additional testing such as skin biopsy, serum biomarkers, and genetic testing can be confirmatory. An accurate diagnosis is essential for the management and dis...
Source: Immunology and Allergy Clinics of North America - April 12, 2023 Category: Allergy & Immunology Authors: Matthew Koslow, David A. Lynch, Carlyne D. Cool, Steve D. Groshong, Gregory P. Downey Source Type: research

Histopathologic Features of Skin Biopsies in Patients with Hereditary Alpha Tryptasemia
We examined the association between HaT and abnormalities of collagen and elastin deposition on skin biopsies of patients with HaT.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Lindsey Smee, Scott Walsh, Peter Vadas Source Type: research

Cobalt nanoparticles cause allergic contact dermatitis in  humans
CONCLUSIONS: CoNPs potently elicit immune responses in Co-sensitized individuals. Even though patch testing with CoNPs resulted in a lower skin dose than CoCl2, identical immunological profiles were present. Further research is needed to identify the potential harm of CoNPs to human health.PMID:36637098 | DOI:10.1093/bjd/ljac043
Source: The British Journal of Dermatology - January 13, 2023 Category: Dermatology Authors: Klara Midander Paulina Werner Marl éne Isaksson Lukas Wisgrill Carola Lid én Nanna Fyhrquist Anneli Julander Source Type: research

An Indonesian female with Stevens-Johnson syndrome mimicking cutaneous lupus: A case report
CONCLUSION: SJS/TEN can occur in SLE patients. The correct diagnosis can reduce the patient's mortality and morbidity.PMID:36268425 | PMC:PMC9577632 | DOI:10.1016/j.amsu.2022.104644
Source: Annals of Medicine - October 21, 2022 Category: Internal Medicine Authors: Nadya Meilinar Samson None Awalia Source Type: research

Diagnostic and therapeutic dilemma in Stevens –Johnson syndrome-like acute graft-versus-host disease after liver transplantation: A case report
ConclusionWe demonstrated a diagnostic strategy for OLT-aGVHD. Targeting therapy with anti-TNF-α blockade and a temporary withdrawal of traditional immunosuppressants may be among effective and safe therapeutic options of OLT-aGVHD for those with severe sepsis.
Source: Frontiers in Immunology - August 18, 2022 Category: Allergy & Immunology Source Type: research

Study protocol: Australasian Registry of Severe Cutaneous Adverse Reactions (AUS-SCAR)
This study was reviewed and approved by the Austin Health Human Research Ethics Committee (HREC/50791/Austin-19). Results will be published in peer-reviewed journals and presented at relevant conferences. Trial registration number Australian New Zealand Clinical Trials Registry (ACTRN12619000241134).
Source: BMJ Open - August 17, 2022 Category: General Medicine Authors: James, F., Goh, M. S. Y., Mouhtouris, E., Vogrin, S., Chua, K. Y. L., Holmes, N. E., Awad, A., Copaescu, A.-M., De Luca, J. F., Zubrinich, C., Gin, D., Cleland, H., Douglas, A., Kern, J. S., Katelaris, C. H., Thien, F., Barnes, S., Yun, J., Tong, W., Smit Tags: Open access, Immunology (including allergy) Source Type: research

Telemedicine in Drug Hypersensitivity
This review focuses on the current applications of telemedicine for drug hypersensitivity reactions. Telemedicine holds promise as a tool to risk-stratify patients with drug hypersensitivity, for both evaluation of penicillin allergies and severe cutaneous adverse reactions. Although telemedicine may not fully replace in-person assessment owing to the need for testing, challenges, and in-person physical examination or skin biopsy, it may allow for risk stratification whereby some in-person visits may not be necessary. Electronic consults have also emerged along with telemedicine as a tool for drug allergy evaluations.
Source: Immunology and Allergy Clinics of North America - March 31, 2022 Category: Allergy & Immunology Authors: Deva Wells, Katherine L. DeNiro, Allison Ramsey Source Type: research

What Are Some Mast Cell Disorders?
Discussion Mast cells (MCs) were first discovered by Paul Ehrlich in 1878. Previously in 1869, Nettleship and Tay described a toddler with chronic urticaria and a brown skin lesion which is believed to be the first reported case of mastocytosis. Urticaria pigmentosa was a term first used by Sangster in 1878, and in 1936 the term mastocytosis was used. “Mast cells first evolved 500 million years ago in Ascidians (sea squirts), providing host innate immunity against bacteria and parasites….MCs gained additional functions regulating inflammation, wound healing, coagulation, adaptive immunity and acute allergic res...
Source: PediatricEducation.org - February 21, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Mast Cells are Locally Activated and Respond to MRGPRX2 Stimulation in Atopic Dermatitis Ex Vivo Skin Biopsies
Atopic dermatitis (AD) is characterized largely by type 2 inflammation of the skin and often debilitating symptoms such as pruritis. Mast cells (MCs) and eosinophils are considered drivers of itch in skin diseases via crosstalk with sensory neurons. The identification of MRGPRX2 as a MC-specific receptor for a broad range of neuropeptides further implicates crosstalk between MCs and nerves in neurogenic inflammation. While MCs and eosinophils have been shown to be elevated in AD, their roles in pathogenesis remain poorly understood.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Melina Butuci, Zachary Benet, Alan Wong, Julia Schanin, Alan Xu, Amol Kamboj, Brad Youngblood Source Type: research