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Procedure: Skin Biopsy

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Total 252 results found since Jan 2013.

IgE-Mediated allergy to wheat in a child with celiac disease ¿ a case report
Conclusion: To our knowledge, this is the first report of a patient with celiac disease and concomitant IgE-mediated allergy to wheat presenting with immediate symptoms in two body systems. Although the pathophysiology of these diseases is different, this case demonstrates that they are not exclusive of one another. In patients who develop unexplained symptoms consistent with IgE-mediated allergy, an allergy assessment should be considered.
Source: Allergy, Asthma and Clinical Immunology - November 10, 2014 Category: Allergy & Immunology Authors: Tiffany WongHin KoEdmond Chan Source Type: research

Stevens Johnson Syndrome versus Jarisch Herxheimer Reaction in an HIV positive patient with secondary syphilis.
CONCLUSIONS: although the diagnosis of SJS has established criteria, the possibility of overlap with infectious illness and/or with its treatment, may complicate the diagnosis. PMID: 29076438 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - October 29, 2017 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Sensitivity, specificity, and predictive value of oral mucosal brush biopsy for the diagnosis of peanut allergy
ConclusionIn this pilot study, oral MBB demonstrated high sensitivity and specificity for screening individuals with and without oral cavity clinical reactivity to peanuts and may represent a potentially useful testing method for the diagnosis of peanut allergy in the future.
Source: International Forum of Allergy and Rhinology - February 5, 2019 Category: Allergy & Immunology Authors: Yu Ting He, William R. Reisacher Tags: ORIGINAL ARTICLE Source Type: research

Anaphylaxis After Hymenoptera Sting: Is It Venom Allergy, A Clonal Disorder, or Both?
Publication date: Available online 7 April 2015 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Mariana C. Castells , Jason L. Hornick , Cem Akin A 47-year-old man presented with loss of consciousness 5 minutes after being stung by a yellow jacket in his backyard. Epinephrine and fluids were required for resuscitation. Allergy evaluation revealed specific IgE to yellow jacket and honeybee, and the patient was started on venom immunotherapy. He had systemic reactions during buildup and a severe anaphylactic episode requiring 3 doses of intramuscular epinephrine at maintenance doses. Immunothe...
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 7, 2015 Category: Allergy & Immunology Source Type: research

Two cases of elevated tryptase in abdominal aortic aneurysm.
DISCUSSION: The elevated tryptase levels were correlated to abdominal aneurysm in both patients. In fact, post-surgery tryptase levels dramatically decreased. These two cases demonstrate that high tryptase levels in subjects with a history of hymenoptera venom anaphylaxis can be associated to undiagnosed aneurysmatic disease. PMID: 25781196 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - June 4, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Fixed Food Eruption Caused by Actinidia arguta (Hardy Kiwi): A Case Report and Literature Review.
This report describes the first case of FFE caused by hardy kiwi leaves, known as Daraesun in Korean, confirmed by oral provocation tests and skin biopsy. PMID: 28102064 [PubMed]
Source: Allergy, Asthma and Immunology Research - January 21, 2017 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Celiac Disease and Wheat Allergy: A Growing Association?
We report 2 patients with celiac disease and a gluten-free diet who developed WA consistent in anaphylaxis and an eyelid angioedema, respectively, through accidental wheat exposure. A serum study and an intestinal biopsy confirmed celiac disease. Both patients were studied with a skin prick test and serum-specific IgE, with a diagnosis of WA.Discussion: In patients with celiac disease, the trace amounts of cereals present in gluten-free food could act as a sensitization factor, and probably patients with persistent symptoms (despite a gluten-free diet) are experiencing WA symptoms rather than celiac disease symptoms. The n...
Source: International Archives of Allergy and Immunology - May 30, 2018 Category: Allergy & Immunology Source Type: research

Nummular Eczema: An Updated Review.
CONCLUSION: With proper treatment, nummular eczema can be cleared over a few weeks, although the course can be chronic and characterized by relapses and remissions. Moisturizing of the skin and avoidance of identifiable exacerbating factors such as hot water baths and harsh soaps may reduce the frequency of recurrence. Diseases that present with annular lesions may mimic nummular eczema and the differential diagnosis is broad. As such, physicians must be familiar with this condition so that an accurate diagnosis can be made, and appropriate treatment initiated. PMID: 32778043 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - August 13, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Induction of accelerated reactions to amoxicillin by T-cell effector mechanisms.
CONCLUSION: We found that accelerated reactions to β-lactams are mediated by effector T cells. The increase in different T-cell markers and a positive LTT result to amoxicillin, in parallel with the occurrence of symptoms after challenge, support this mechanism. PMID: 23535091 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - April 1, 2013 Category: Allergy & Immunology Authors: Gómez E, Blanca-Lopez N, Salas M, Canto G, Campo P, Torres MJ, Mayorga C, Blanca M Tags: Ann Allergy Asthma Immunol Source Type: research

Increased epidermal filaggrin in chronic idiopathic urticaria is associated with severity of urticaria.
CONCLUSION: Filaggrin is overexpressed in lesional CIU skin, and increased filaggrin expression is positively correlated with urticaria severity in CIU. Altered filaggrin expression has physiologic effects on transepidermal water loss and pH in the skin of patients with CIU, suggesting increased barrier function compared with skin from patients with AD. PMID: 24726196 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 10, 2014 Category: Allergy & Immunology Authors: Ye YM, Kim BE, Shin YS, Park HS, Leung DY Tags: Ann Allergy Asthma Immunol Source Type: research

A case of eosinophilic fasciitis presenting as pitting edema of the lower extremities.
We report a 19-year-old female who presented with pitting edema in both lower extremities. She had a history of excessive physical activity before her symptoms developed. Physical examination revealed 2+ pitting edema in both lower legs. She complained of mild pain in both knee joints and feet, with no tenderness or heating sensations. Laboratory results were unremarkable except for severe eosinophilia. Parasite infection, venous thrombosis, and cardiac and renal problems were excluded. A magnetic resonance imaging study of both lower extremities revealed increased signal intensity in the subcutaneous lesions, consistent w...
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Stevens-Johnson syndrome and toxic epidermal necrolysis.
Authors: Harr T, French LE Abstract Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare but severe adverse cutaneous drug reactions that are to be considered medical emergencies. The average reported mortality rate for SJS is 1-5%, and up to 25-35% for TEN. TEN and SJS are characterized by more or less extensive painful erythematous and erosive lesions of the skin, conjunctiva and mucous membranes resulting from massive apoptosis of epithelial cells, and are considered to be two ends of a spectrum of severe epidermolytic adverse cutaneous drug reactions, differing only by their extent of sk...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Hypereosinophilic syndrome due to ETV6/PDGFR-beta gene translocation - a diagnostic and therapeutic challenge.
CONCLUSION: This patient was diagnosed with a rare myeloproliferative variant of hypereosinophilic syndrome due to a t(5;12) ETV6/PDGFR-beta translocation. Imatinib mesylate, previously used successfully in syndromes associated with PDFGR-alpha mutations, showed efficacy in the context of this mutation as well. PMID: 25599554 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - June 4, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

IL-31 and IL-33 circulating levels in allergic contact dermatitis.
Authors: Guarneri F, Minciullo PL, Mannucci C, Calapai F, Saitta S, Cannavò SP, Gangemi S Abstract Enhanced IL-31 expression in skin biopsies is present in allergic contact dermatitis (ACD). IL-33 expression is induced in keratinocytes and in skin of ACD patients. This overexpression is present in both allergic and irritant conditions. The aim of this work was to test the systemic involvement of IL-31 and IL-33 in ACD. IL-31 levels were significantly higher in patients than in controls. IL-33 serum levels, on the contrary, were similar in patients and controls. This work shows a possible systemic involvement of IL...
Source: European Annals of Allergy and Clinical Immunology - September 12, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research