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Total 226 results found since Jan 2013.

Factors Associated with Development of Food Allergy in Young Children after Liver Transplantation: A Retrospective Analysis of 10  Years' Experience
Conclusions We identified eczema at liver transplantation as a significant risk factor for the development of IgE-mediated food allergy after liver transplantation, but not non–IgE-mediated food allergy. Our findings may contribute to a better understanding of the susceptible subgroup requiring special caution and to the establishment of effective strategies for prevention.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 24, 2017 Category: Allergy & Immunology Source Type: research

Life-saving transplant results in end to peanut allergy
Not only can bone marrow transplants be life-saving for children with acute lymphocytic leukemia, they may also cure peanut allergies. According to research presented during the American College of Allergy, Asthma and Immunology's (ACAAI) Annual Scientific Meeting, a 10-year-old boy no longer had a peanut allergy after undergoing a bone marrow transplant. "It has been reported that bone marrow and liver transplants can transfer peanut allergy from donor to recipient," said allergist Yong Luo, MD, Ph.D., ACAAI member and lead study author...
Source: Health News from Medical News Today - November 12, 2013 Category: Consumer Health News Tags: Allergy Source Type: news

Pediatric Post-Transplantation Food Allergy Experience at a Large U.S. Tertiary Care Center
New-onset food allergy following transplantation is a described phenomenon, with the first case being reported in 1997.1,2 While post-transplantation food allergy (PTFA) is most common following liver transplantation with a prevalence ranging from 5.6 – 38%, new-onset food allergy has also been described following bone marrow transplantation (BMT).2-4 Tacrolimus, a medication used less frequently in BMT compared to solid organ transplantation, has been identified as a potentially modifiable risk factor for PTFA.
Source: Annals of Allergy, Asthma and Immunology - August 2, 2019 Category: Allergy & Immunology Authors: Ashley Lynn Devonshire, Lauren Christine Balmert, Rajesh Kumar Tags: Letters Source Type: research

Pediatric posttransplantation food allergy experience at a large US tertiary care center
The first case of new-onset food allergy after transplantation was reported in 1997.1,2 Although posttransplantation food allergy (PTFA) is most common after liver transplantation, with a prevalence ranging from 5.6% to 38%, new-onset food allergy has also been described after bone marrow transplantation (BMT).2 –4 Tacrolimus, a medication used less frequently in BMT compared with solid organ transplantation, has been identified as a potentially modifiable risk factor for PTFA.2 Tacrolimus creates an immunologic imbalance that favors a TH2 response and increases intestinal permeability, which may increase allergen exposure via the gut.
Source: Annals of Allergy, Asthma and Immunology - August 2, 2019 Category: Allergy & Immunology Authors: Ashley Lynn Devonshire, Lauren Christine Balmert, Rajesh Kumar Tags: Letters Source Type: research

Prospective evaluation of IgE and eosinophilia in food allergy after liver transplantation
This study further enlightens the pathophysiological mechanism of food allergy (FA) after liver transplantation (LT). However, the interval between the time FA happened and the time of the blood testing for analysis was considerably long. This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - September 27, 2015 Category: Allergy & Immunology Authors: Ozlem Yılmaz Ozbek Tags: Correspondence Source Type: research

A007 impact of penicillin allergy label in liver transplant recipients during transplant hospitalization
Self-reported penicillin (PCN) allergy is associated with broad-spectrum antibiotic use, increased antibiotic resistance, extended hospital length of stay (LoS), and increased risk of in-hospital complications including surgical site infections (SSI) and C. difficile infection (CDI). We aimed to determine the impact of self-reported PCN allergy in liver transplant recipients (LTR).
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: G. Motoa, I. Carrillo-Martin, N. Chamorro-Pareja, D. Haehn, J. Mendez, H. Wadei, D. Hodge, D. Lee, W. Bosch, A. Gonzalez-Estrada Source Type: research

Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in pediatric liver transplant patients
ConclusionsLT has an impact on humoral immunity, remarkably in those patients developing FA.The increase in serum markers of mucosal IgA, food allergen specific IgA and cTfh cells observed in LTFA, point towards a disturbance in intestinal immune homeostasis in this patient group.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - February 1, 2015 Category: Allergy & Immunology Authors: Ruth De Bruyne, Philippe Gevaert, Myriam Van Winckel, Natalie De Ruyck, Aurelie Minne, Delfien Bogaert, Stephanie Van Biervliet, Saskia Vande VeldeD, Francoise Smets, Etienne Sokal, Fréderic Gottrand, Jérémy Vanhelst, Bruno Detry, Charles Pilette, Bart Tags: Original Article‐Clinical Mechanisms in Allergic Disease Source Type: research

Evaluation of the Effect of Ascorbic Acid Administration on Gene Expression Level of IL-6 and TNF-α Cytokines in Deceased Donors.
Abstract Brain death is associated with increased inflammatory cytokines levels and poor graft quality to transplant. We aimed to evaluate the impact of Ascorbic Acid (AA) on the inflammatory status of Brain-Dead Donors (BDDs). Forty BDDs were randomly divided into two groups. Donor treatment (n=20) consisted of 100 mg/kg AA infusion 6 hours before donor operation and subsequent infusion of 100 mg/kg/p6h until organ removal. Blood samples were taken at three times, 6 hours before donor surgery (TP1), immediately after laparotomy (TP2), and before organ removal (TP3). Gene expression level and serum concentration o...
Source: Iranian Journal of Allergy, Asthma and Immunology - March 18, 2015 Category: Allergy & Immunology Authors: Kazemi M, Tabei SM, Najafizadeh K, Mehrabi Sisakht J, Milani S, Khosravi MB Tags: Iran J Allergy Asthma Immunol Source Type: research

A severe case of minocycline-induced DRESS resulting in liver transplantation and autoimmune sequelae.
PMID: 26782675 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 9, 2016 Category: Allergy & Immunology Authors: Lan J, Lahoti A, Lew DB Tags: Ann Allergy Asthma Immunol Source Type: research

Microbiome Regulation of Autoimmune, Gut and Liver associated Diseases.
Abstract Extensive analysis of the complexity and diversity of microbiota using metagenomics in the gut and other body sites has provided evidence that dysbiosis occurs in many disease states. With the application of next generation sequencing technology this research is starting to uncover the impact of microbiota on metabolic, physiological and immunological pathways and elucidate the cellular and molecular mechanisms involved. To highlight these advances we have focused on autoimmunity and gut and liver related diseases and discuss the opportunities and challenges of translating microbiome research towards its ...
Source: Inflammation and Allergy Drug Targets - January 28, 2016 Category: Allergy & Immunology Authors: Singh B Tags: Inflamm Allergy Drug Targets Source Type: research

Comments on "Evaluation of Interleukin-21, 23 and 27 mRNA Expression and Protein Level in Liver Transplant Patients".
Abstract No  Abstract#. PMID: 31522442 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - June 7, 2019 Category: Allergy & Immunology Authors: Soleimani M Tags: Iran J Allergy Asthma Immunol Source Type: research

Impact of Beta-lactam Allergy Label in Liver Transplant Recipients
Publication date: Available online 15 April 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Gabriel Motoa, Ismael Carrillo-Martin, Natalia Chamorro-Pareja, Daniela Haehn, Julio Mendez, Hani M. Wadei, David O. Hodge, David D. Lee, Wendelyn Bosch, Alexei Gonzalez-Estrada
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 16, 2020 Category: Allergy & Immunology Source Type: research

Long‐term follow‐up of de novo allergy in pediatric liver transplantation – 10 yr experience of a single center
Abstract We conducted a study to clarify the incidence, clinical course, and risk factors of de novo allergies after liver transplantation. Ninety‐three patients who had been followed longer than one yr and who had no previous allergy history were included. Forty‐two patients (45.2%) developed de novo allergy. Of them, food allergy developed in 35 (37.6%). Respiratory allergy was observed in three (3.2%), and a patient (1.1%) had drug allergy. Fifty‐two (55.9%) of the 93 patients developed eosinophilia. The median age of patients with de novo allergy was 15 months (IR 11.3–20 months). De novo allergy developed fi...
Source: Pediatric Transplantation - February 1, 2013 Category: Transplant Surgery Authors: Yoon Lee, Yoo Min Lee, Mi Jin Kim, Suk Koo Lee, Yon Ho Choe Tags: Original Article Source Type: research

High Frequency of Concomitant Food Allergy Development and Autoantibody Formation in Children Who Have Undergone Liver Transplantation
Conclusions. In contrast to respiratory allergy, food allergy and autoantibody formation occurred together in the same children who underwent liver transplantation at a frequency higher than would be expected by chance. This may reflect an underlying immune dysregulation that impairs immune tolerance to both food allergens and autoantigens.
Source: Transplantation - October 29, 2019 Category: Transplant Surgery Tags: Original Clinical Science–Liver Source Type: research

Post-transplantation Development of Food Allergies
AbstractPurpose of ReviewThe development of food allergies is increasingly being recognized as a post-solid organ transplant complication. In this article, we review the spectrum of post-transplant food allergy development and the proposed mechanisms for de novo food allergies and the clinical significance they pose.Recent FindingsThe development of new food allergies is disproportionately associated with pediatric liver transplants, where it occurs in up to 38% of select populations. The mechanism of food allergy development is not completely understood; however, it is likely promoted by unbalanced immune suppression.Summ...
Source: Current Allergy and Asthma Reports - January 29, 2018 Category: Allergy & Immunology Source Type: research