Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in pediatric liver transplant patients

ConclusionsLT has an impact on humoral immunity, remarkably in those patients developing FA.The increase in serum markers of mucosal IgA, food allergen specific IgA and cTfh cells observed in LTFA, point towards a disturbance in intestinal immune homeostasis in this patient group.This article is protected by copyright. All rights reserved.

Source: Clinical and Experimental Allergy - February 1, 2015 Category: Allergy & Immunology Authors: Ruth De Bruyne, Philippe Gevaert, Myriam Van Winckel, Natalie De Ruyck, Aurelie Minne, Delfien Bogaert, Stephanie Van Biervliet, Saskia Vande VeldeD, Francoise Smets, Etienne Sokal, Fréderic Gottrand, Jérémy Vanhelst, Bruno Detry, Charles Pilette, Bart Tags: Original Article‐Clinical Mechanisms in Allergic Disease Source Type: research