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Drug: Methylprednisolone
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EMA Begins Review of Select Injectable Allergy Medications EMA Begins Review of Select Injectable Allergy Medications
Injectable allergy medications containing methylprednisolone may pose risks to those who are allergic to cows ' milk.News Alerts
Source: Medscape Allergy Headlines - December 2, 2016 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Alert Source Type: news
XXIV World Allergy Congress 2015
Table of Contents
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
Jae-Min Shin, Heung-Man Lee, Il-Ho Park
A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines
Hyun-Sun Yoon, Gyeong Yul Park
A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome
Margit Zeher
A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research
Immediate hypersensitivity reactions to corticosteroids.
CONCLUSION: Corticosteroids seem to be rare causes of immediate hypersensitivity reactions but possibly are misdiagnosed or under-reported relative to their worldwide use. Physicians should be cognizant of this entity and identify safe alternative preparations.
PMID: 26211812 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 23, 2015 Category: Allergy & Immunology Authors: Patel A, Bahna SL Tags: Ann Allergy Asthma Immunol Source Type: research
Skin testing for immediate hypersensitivity to corticosteroids – a case series and literature review
ConclusionsSkin testing can provide sufficient evidence to diagnose allergy in patients with a clear history of immediate hypersensitivity to corticosteroids such as anaphylaxis. Both skin prick and intradermal tests should be used. There is evidence of cross‐reactivity between steroids so a panel is recommended. False positive and false negative reactions do occur, however the frequency is unknown. Challenge remains the only definitive way to demonstrate a safe alternative to use.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - October 25, 2014 Category: Allergy & Immunology Authors: A. Baker, M. Empson, R. The, P. Fitzharris Tags: Original Article‐Clinical Allergy Source Type: research
Effects of Methylprednisolone Pulse Therapy on Refractory Mycoplasma pneumoniae Pneumonia in Children.
CONCLUSIONS: Three-day methylprednisolone pulse therapy could be applied to treatment of refractory M. pneumoniae pneumonia despite appropriate antibiotic therapy and appeared to be efficacious and well-tolerated.
PMID: 24404389 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Skin testing for immediate hypersensitivity to corticosteroids: a case series and literature review
ConclusionsSkin testing can provide sufficient evidence to diagnose allergy in patients with a clear history of immediate hypersensitivity to corticosteroids such as anaphylaxis. Both skin prick and intradermal tests should be used. There is evidence of cross‐reactivity between steroids so a panel is recommended. False positive and false negative reactions do occur, however the frequency is unknown. Challenge remains the only definitive way to demonstrate a safe alternative to use.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - October 24, 2014 Category: Allergy & Immunology Authors: Andrew Baker, Marianne Empson, Roy The, Penny Fitzharris Tags: Original Article‐Clinical Allergy Source Type: research
Angiotensin Converting Enzyme Inhibitor-related Angioedema: A Case of an Unexpected Death.
Abstract
Angioedema is an asymmetric non-pitting oedema on face, lips, tongue and mucous membranes; any delay in diagnosis and treatment can be fatal. Treatment with lisinopril as an angiotensin converting enzyme (ACE) inhibitor, can be a reason of angioedema. Here we report a case who developed oral-facial edema four years after using lisinopril/hydrochlorothiazide. Laryngeal oedema is a main cause of death in angioedema. The treatment of choice in angioedema including fresh frozen plasma, C1 inhibitor concentrations and BRK-2 antagonists (bradykinin B2 receptor antagonists) were used. In this case; a 77 years ...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 1, 2015 Category: Allergy & Immunology Authors: Atalay E, Özdemir MT, Çiğsar G, Omurca F, Aslan N, Yildiz M, Gey ZB Tags: Iran J Allergy Asthma Immunol Source Type: research
Stratified premedication strategy for the prevention of contrast media hypersensitivity in high-risk patients.
CONCLUSION: In a total severity-based stratified prophylaxis regimens and changing iodinated contrast media can be considered in patients with a history of previous hypersensitivity reaction to iodinated contrast media to reduce the risk of breakthrough reactions.
PMID: 28087383 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 9, 2017 Category: Allergy & Immunology Authors: Lee SY, Yang MS, Choi YH, Park CM, Park HW, Cho SH, Kang HR Tags: Ann Allergy Asthma Immunol Source Type: research
Comparison of Corticosteroids by 3 Approaches to the Treatment of Chronic Rhinosinusitis With Nasal Polyps.
CONCLUSIONS: A short course of BIS transnasal nebulization is more efficacious compared to BNS in the management of ECRSwNP and is safer than oral methylprednisolone with respect to hypothalamic-pituitary-adrenal axis function.
PMID: 31172717 [PubMed]
Source: Allergy, Asthma and Immunology Research - June 8, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Familial clustering of hypereosinophilic diseases treated with mepolizumab: a case report from Japan.
We describe a female diagnosed with non-allergic asthma. On March 24, 2016, examination of the skin-biopsy specimen revealed dense eosinophilic infiltration, and the Fip-1-like 1-platelet-derived growth factor receptor a fusion gene in peripheral blood mononuclear cells was negative. She was diagnosed with idiopathic hypereosinophilic syndrome. She was treated with intravenous methylprednisolone (MPSL), and subsequent oral MPSL. Then, she started to receive a monthly mepolizumab in June 2016, and successfully withdrew from daily use of oral MPSL. The patient has a mother diagnosed with non-allergic asthma. In February 2005...
Source: European Annals of Allergy and Clinical Immunology - October 10, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Antiepileptic Hypersensitivity Syndrome to Phenobarbital: A Case Report.
Abstract
Phenobarbital is still one of the most commonly used medical treatments for different types of seizures. It has numerous different side-effects. Antiepileptic hypersensitivity syndrome (AHS) is a rare and potentially life-threatening adverse reaction to aromatic anticonvulsants such as phenobarbital. Its characteristic features are fever, rash, and lymphadenopathy with different severity of hematologic abnormalities. This case report presents a 26-month-old girl that developed fever, disseminated maculopapular rash, petechiae and thrombocytopenia two weeks after the initiation of phenobarbital prescribed ...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 22, 2019 Category: Allergy & Immunology Authors: Nafei Z, Behniafard N, Shefai F Tags: Iran J Allergy Asthma Immunol Source Type: research
Severe forms of food allergy.
CONCLUSION: Severe food allergy may occur in the form of anaphylaxis and food-protein-induced enterocolitis syndrome, which are increasingly observed in the pediatric emergency room; hence, pediatricians must be alert so they can provide the immediate diagnosis and treatment.
PMID: 28941390 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - September 20, 2017 Category: Pediatrics Authors: Sarinho ESC, Lins MDGM Tags: J Pediatr (Rio J) Source Type: research
Are the Spanish baseline series markers sufficient to detect contact allergy to corticosteroids in Spain? A GEIDAC prospective study
ConclusionsMore than half of the patients who were allergic to the additionally tested corticosteroids were not detected with the corticosteroid allergy markers. An update of the corticosteroid allergy screening markers is encouraged, with consideration of group 3 corticosteroids.
Source: Contact Dermatitis - September 27, 2017 Category: Dermatology Authors: Pedro Mercader ‐García, María A. Pastor‐Nieto, Ignacio García‐Doval, Ana Giménez‐Arnau, Ricardo González‐Pérez, Virginia Fernández‐Redondo, Ester Serra‐Baldrich, Susana Cordoba‐Guijarro, María E. Gatica‐Ortega, Juan F. Silvestre Tags: Original Article Source Type: research
Chronic Spontaneous Urticaria: A Survey of 852 Cases of Childhood-Onset Systemic Lupus Erythematosus
The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demographic data, clinical manifestations, disease activity/damage, laboratory abnormalities and treatment. Methods: A retrospective multicenter cohort study (Brazilian cSLE group) was performed in 10 Pediatric Rheumatology services and included 852 cSLE patients. CSU was diagnosed according to the guidelines of the European Academy of Allergy and Clinical Immunology, the Global Allergy and Asthma European Network, the European Dermatology Forum and the World Allergy Organization. Patients with CSU (evaluated at urticaria d...
Source: International Archives of Allergy and Immunology - August 24, 2015 Category: Allergy & Immunology Source Type: research
Elderly-Onset Neuromyelitis Optica Spectrum Disorder with Pre-Existing Prednisone Allergy
We present a case of an 82-year-old man with new-onset neuromyelitis optica (NMO) spectrum disorder, the treatment of which was complicated by a severe pre-existing prednisone allergy. His age caused much initial doubt about his diagnosis, and his corticosteroid allergy altered our management as we attempted to minimize risk to the patient. Our patient was a healthy 82-year-old, right-handed man who presented with sensory loss of the bilateral lower extremities and progressive, painless vision loss. MRI showed bilateral pre-chiasmatic optic nerve and optic chiasm enhancement, along with enhancement within the thoracic spin...
Source: Case Reports in Neurology - January 23, 2018 Category: Neurology Source Type: research
